- Conditions
- Delirium, Sleep
- Interventions
- Dexmedetomidine, Placebo
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 522 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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- Conditions
- Awake Fiberoptic Intubation
- Interventions
- Dexmedetomidine HCL Injection, Placebo
- Drug
- Lead sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 124 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 17
- States / cities
- Birmingham, Alabama • Loma Linda, California • Miami, Florida + 12 more
- Conditions
- Mechanically Ventilated and Intubated Subjects
- Interventions
- Dexmedetomidine HCL Injection, Midazolam Injection
- Drug
- Lead sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 420 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 78
- States / cities
- Birmingham, Alabama • Chandler, Arizona • Phoenix, Arizona + 75 more
- Conditions
- Rapid Atrial Fibrillation, Heart Rate Control
- Interventions
- Dexmedetomidine Hydrochloride, Normal Saline
- Drug · Other
- Lead sponsor
- Stony Brook University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Stony Brook, New York
- Conditions
- Hypotensive Anesthesia, Orthognathic Surgery
- Interventions
- Dexmedetomidine, Nicardipine, Labetalol
- Drug
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts