- Conditions
- Anesthesia, Pain
- Interventions
- Dexmedetomidine, Propofol, Fentanyl, Peripheral Nerve Stimulation, Placebo
- Drug · Device
- Lead sponsor
- Keith M Vogt
- Other
- Eligibility
- 18 Years to 39 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
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- Conditions
- Alzheimer Disease
- Interventions
- Dexmedetomidine
- Drug
- Lead sponsor
- Neurological Associates of West Los Angeles
- Other
- Eligibility
- 18 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Santa Monica, California
- Conditions
- Mental Function
- Interventions
- Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation, Anterior insular cortex (AIC) pulsation, Central thalamus (CT) pulsation
- Procedure · Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Healthy, Covert Consciousness
- Interventions
- Dexmedetomidine (+propofol as indicated), Ketamine
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan