- Conditions
- Total Knee Arthroplasty (TKA)
- Interventions
- Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG)
- Combination Product · Device
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 119
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Unconsciousness, Consciousness
- Interventions
- Dexmedetomidine, Ketamine, Propofol, Midazolam
- Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Chronic Pain
- Interventions
- Dexmedetomidine, Placebo Saline
- Drug · Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Retinal Detachment
- Interventions
- Dexmedetomidine infusion, propofol
- Drug
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Newark, New Jersey
- Conditions
- Sleep
- Interventions
- Dexmedetomidine, Propofol, Midazolam, Fentanyl, Isoflurane
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 21 Years to 50 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Obstructive Sleep Apnea
- Interventions
- Propofol sedation, Dexmedetomidine sedation
- Drug
- Lead sponsor
- Erin Kirkham
- Other
- Eligibility
- 3 Years to 11 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Enhanced Recovery After Surgery in a Pediatric Population
- Interventions
- Caffeine citrate 15mg/kg, 0.9% Sodium Citrate
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 3 Years to 12 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Sedative Adverse Reaction
- Interventions
- Propofol, Dexmedetomidine
- Drug
- Lead sponsor
- Children's Healthcare of Atlanta
- Other
- Eligibility
- 3 Months to 36 Months
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Conscious Sedation, Distal Radius Fracture
- Interventions
- Dexmedetomidine, Ketamine
- Drug
- Lead sponsor
- Phoenix Children's Hospital
- Other
- Eligibility
- 2 Years to 18 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- COPD
- Interventions
- IN-DEX 1.0 mcg/kg, intranasal saline, IN-DEX 1.5 mcg/kg, intranasal saline, Placebo - Saline
- Drug
- Lead sponsor
- Dayton VA Medical Center
- Federal
- Eligibility
- 45 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Dayton, Ohio
- Conditions
- Dexmedetomidine, Mechanical Ventilation Complication, Critically Ill
- Interventions
- Fentanyl, Dexmedetomidine
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 19
- States / cities
- Little Rock, Arkansas • Gainesville, Florida • Indianapolis, Indiana + 15 more
- Conditions
- Laceration of Skin, Anxiety, Discharge Time
- Interventions
- Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine
- Drug
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 1 Year to 5 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Ventricular Tachycardia, Ventricular Arrhythmias, Ventricular Fibrillation, Recurrent Ventricular Tachycardia
- Interventions
- Dexmedetomidine, Normal saline
- Drug
- Lead sponsor
- Ottawa Heart Institute Research Corporation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Sepsis, Respiratory Failure, Agitation
- Interventions
- Propofol, Dexmedetomidine, Fentanyl
- Drug
- Lead sponsor
- Texas Tech University Health Sciences Center
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- MRI Sedation
- Interventions
- Dexmedetomidine
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 3 Years to 12 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Duchenne Muscular Dystrophy
- Interventions
- Ketamine, Dexmedetomidine
- Drug
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- Male only
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Saccadic Eye Movements
- Interventions
- propofol, dexmedetomidine, Midazolam, saline placebo
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 19 Years to 65 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Obstructive Sleep Apnea, Down Syndrome
- Interventions
- DISE-Directed Surgery, Adenotonsillectomy
- Procedure
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 7
- States / cities
- Aurora, Colorado • Ann Arbor, Michigan • Cincinnati, Ohio + 4 more
- Conditions
- Delirium, Agitation
- Interventions
- Dexmedetomidine, Standard of Care
- Drug · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Pain
- Interventions
- dexmedetomidine hydrochloride
- Drug
- Lead sponsor
- Lahey Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Burlington, Massachusetts
- Conditions
- Safety and Efficacy of Intranasal Dexmedetomidine
- Interventions
- Dexmedetomidine, Midazolam Hydrochloride, Nitrous Oxide
- Drug
- Lead sponsor
- Bon Secours Pediatric Dental Associates
- Other
- Eligibility
- 3 Years to 6 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Parkinson's Disease, Essential Tremor, Dystonia
- Interventions
- Dexmedetomidine Hydrochloride Infusion, Normal Saline
- Drug
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Critical Illness, Sedation Complication, Delirium
- Interventions
- Dexmedetomidine Hydrochloride - Cycling, Fentanyl - PICU Standard, Dexmedetomidine Hydrochloride - PICU Standard
- Drug
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 12 Years to 17 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Sedation, Pain
- Interventions
- Dexmedetomidine
- Drug
- Lead sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 12 Months to 23 Months
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania