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ClinicalTrials.gov public records Last synced Oct 12, 2026, 3:38 AM EDT

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Showing 25–38 of 38 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Diclofenac 1% topical Clear all
Completed Phase 3 Interventional

Efficacy and Safety of Diclofenac Sodium Gel in Hand Osteoarthritis

NCT00171665
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diclofenac topical sodium gel 1%
Drug
Lead sponsor
Novartis
Industry
Eligibility
40 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
69
States / cities
Birmingham, Alabama • Calera, Alabama • Montgomery, Alabama + 60 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain

NCT05050448
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
3
States / cities
Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2025 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 4 Interventional Results available

Steroids After Laser Trabeculoplasty for Glaucoma

NCT00981435
View directory record Official record
Conditions
Glaucoma
Interventions
Prednisolone 1%, Ketorolac, Artificial Tears
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Miami, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Diclofenac Sodium Gel in Knee Osteoarthritis

NCT00171626
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diclofenac Topical Sodium Gel 1%
Drug
Lead sponsor
Novartis
Industry
Eligibility
35 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Parsippany, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2012 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 4 Interventional Results available

Diclofenac Sodium Topical Gel to Reduce Injection Site Discomfort in Patients Taking Glatiramer Acetate

NCT01454791
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
diclofenac sodium topical gel, Placebo
Drug · Other
Lead sponsor
Brown, Theodore R., M.D., MPH
Individual
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Kirkland, Washington
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied 4 Times Daily in Subjects With Acute Ankle Sprain

NCT01255423
View directory record Official record
Conditions
Ankle Sprain
Interventions
Diclofenac sodium topical gel 1%, Placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
9
States / cities
Birmingham, Alabama • Aventura, Florida • Hialeah, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Comparative Evaluation of Sustained Acoustic Medicine Device on Circulation

NCT06510062
View directory record Official record
Conditions
Measurement of Circulation on Anatomical Locations of the Body
Interventions
Sustained Acoustic Medicine, 2.5% Diclofenac Patches
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Trumbull, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

NCT06257537
View directory record Official record
Conditions
Osteo Arthritis Knee, Arthritis
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, Sustained Acoustic Device with 0% Diclofenac Patch, 2.5% Diclofenac Patches, SAM Patch
Device · Drug · Other
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
50 Years to 85 Years
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
3
States / cities
Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 2Phase 3 Interventional

Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis

NCT00640939
View directory record Official record
Conditions
Rotator Cuff Tendonitis, Bicipital Tendonitis, Subdeltoid Bursitis of the Shoulder, Subacromial Bursitis of the Shoulder, Medial Epicondylitis of the Elbow, Lateral Epicondylitis of the Elbow, DeQuervain's Tenosynovitis of the Wrist
Interventions
diclofenac sodium, Matching Placebo
Drug
Lead sponsor
Cerimon Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2008 · Synced Oct 12, 2026, 3:38 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

NCT05883241
View directory record Official record
Conditions
Bone Fracture, Fresh Fracture
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, 2.5% Diclofenac Patches
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Trumbull, Connecticut • Lansdowne, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 3 Interventional

Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis of the Knee: Trial I

NCT00546507
View directory record Official record
Conditions
Osteoarthritis
Interventions
TDS-943 (topical diclofenac sodium 4% spray), celecoxib, placebo
Drug · Other
Lead sponsor
Mika Pharma GmbH
Industry
Eligibility
40 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
43
States / cities
Huntsville, Alabama • Mobile, Alabama • Mesa, Arizona + 35 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2010 · Synced Oct 12, 2026, 3:38 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%

NCT02068859
View directory record Official record
Conditions
Knee Pain Chronic, Knee Injuries
Interventions
Diclofenac Cream 8%, Diclofenac Gel 1%
Drug
Lead sponsor
FPR Specialty Pharmacy
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 21, 2014 · Synced Oct 12, 2026, 3:38 AM EDT
Recruiting Not applicable Interventional

The Effects of Patient and Visit Characteristics on Health Outcomes in Knee Osteoarthritis

NCT06574191
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Topical Diclofenac gel 1%
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 12, 2026, 3:38 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

NCT05882812
View directory record Official record
Conditions
Osteo Arthritis Knee, Arthritis
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, Sustained Acoustic Device with 0% Diclofenac Patch, 2.5% Diclofenac Patches
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 12, 2026, 3:38 AM EDT