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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:56 PM EDT

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Showing 745–768 of 2,145 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Diet and Physical Activity Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Paleolithic Based Diet Compared to MyPlate Guidelines, With and Without Exercise, in Women.

NCT02380833
View directory record Official record
Conditions
Healthy
Interventions
MyPlate, MyPlate + Exercise, Paleolithic, Paleolithic + Exercise
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
20 Years to 35 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Clemson, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss Program, Personalized Behavioral Weight Loss Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional

Intensive Diet and Exercise or Standard of Care in Improving Physical Function and Quality of Life in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy

NCT02050906
View directory record Official record
Conditions
Recurrent Prostate Cancer, Stage IV Prostate Cancer
Interventions
behavioral dietary intervention, exercise intervention, behavioral activity counseling, telephone based counseling, quality-of-life assessment, questionnaire administration
Behavioral · Other · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Male only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Oct 19, 2026, 2:56 PM EDT
Recruiting Not applicable Interventional

Protein and Exercise for Postmenopausal Women's Wellbeing

NCT06849817
View directory record Official record
Conditions
Postmenopausal
Interventions
Diet - higher protein, Physical activity and resistance training
Other · Behavioral
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 19, 2026, 2:56 PM EDT
Recruiting Not applicable Interventional

Ultra Crave: An Investigation of Ultra-Processed Food

NCT06044285
View directory record Official record
Conditions
Food Addiction
Interventions
Low UP (meals provided), Low UP (self-guided), Active Control
Other
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 60 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy

NCT03115424
View directory record Official record
Conditions
Obesity
Interventions
Saxenda, Placebos, RYGB
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Phase 2 Interventional

Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2)

NCT07220629
View directory record Official record
Conditions
Obesity
Interventions
NT-0796, Placebo
Drug
Lead sponsor
Rezera (formerly NodThera Limited)
Industry
Eligibility
18 Years to 75 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Mesa, Arizona • Hialeah, Florida • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Bennett Kids PowerUP Project

NCT05858580
View directory record Official record
Conditions
Obesity, Childhood, Type2diabetes
Interventions
Bennett Kids PowerUP Project
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
7 Years to 10 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Active, not recruiting Not applicable Interventional Results available

A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis

NCT05739162
View directory record Official record
Conditions
Obesity, Ulcerative Colitis
Interventions
Apollo Endoscopic Suture System, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years to 69 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Promoting Physical Activity in Older Hispanic/Latino(a) Adults

NCT06362824
View directory record Official record
Conditions
Sedentary Behavior, Physical Inactivity, Alzheimer Disease, Protection Against
Interventions
De Pie Intervention, Active Comparison Group: Healthy Actions And Lifestyles To Avoid Dementia (HALT-AD)
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
55 Years to 89 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
San Diego, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Recruiting No phase listed Observational

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

NCT07132788
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
blood draw, Short Performance Physical Battery, Grip strength test, Six minute walk test, Chest CT scan, Dual-Energy X-ray Absorptiometry Scan, Activity monitoring, 24 hour diet recall, Echocardiogram, Quality of Life Questionnaire (emPHasis 10), International Physical Activity Questionnaire Short Form (IPAQ-SF)
Diagnostic Test · Radiation · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Postpartum Weight Loss in Overweight Women

NCT00212251
View directory record Official record
Conditions
Obesity
Interventions
moderate exercise and healthy, low-fat diet
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Oct 19, 2026, 2:56 PM EDT
Terminated Not applicable Interventional Results available

Activity and Balanced Eating to Reduce Comorbidities and Symptoms of MS

NCT03808545
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Behavioral Intervention for Physical Activity in Multiple Sclerosis (BIPAMS), BIPAMS + Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 18, 2022 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Living Partnerships to Prevent Diabetes in Veterans Pilot Study

NCT02835495
View directory record Official record
Conditions
Pre-diabetes, Obesity
Interventions
HELP Vets Intervention, Individual Education Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Salisbury, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional

Weight Management Demonstration Project: HEALTH

NCT01307280
View directory record Official record
Conditions
Weight Loss
Interventions
RCT1, RCT2, RCT3
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 64 Years
Enrollment
2,395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Swansea, Illinois • Research Triangle Park, North Carolina • Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 26, 2012 · Synced Oct 19, 2026, 2:56 PM EDT
Terminated Not applicable Interventional

An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer

NCT06315296
View directory record Official record
Conditions
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Lung Carcinoma, Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8
Interventions
Behavioral Dietary Intervention, Text Message-Based Navigation Intervention, Internet-Based Intervention, Dietary Counseling and Surveillance, Stereotactic Radiosurgery, Biospecimen Collection, Magnetic Resonance Imaging, Neurocognitive Assessment, Questionnaire Administration, Interview
Behavioral · Other · Radiation + 1 more
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional

Enhancing Adherence in Type 2 Diabetes: The ENHANCE Study

NCT00222846
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetic Nephropathy
Interventions
Attention control, Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2010 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Phase 3 Interventional Results available

Diet in Altering Disease Progression in Patients With Prostate Cancer on Active Surveillance

NCT01238172
View directory record Official record
Conditions
Prostate Cancer
Interventions
dietary education and counseling, prostate cancer foundation booklet
Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
180
States / cities
Fairbanks, Alaska • Scottsdale, Arizona • Bellflower, California + 129 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Oct 19, 2026, 2:56 PM EDT
Recruiting Not applicable Interventional

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

NCT06785324
View directory record Official record
Conditions
Philadelphia Chromosome Negative, B Cell Acute Lymphoblastic Leukemia (B-ALL), B-ALL
Interventions
Nutrition Intervention, Exercise intervention
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 19, 2026, 2:56 PM EDT
Not listed Not applicable Interventional

The Management of Diabetes in Everyday Life Program

NCT02957513
View directory record Official record
Conditions
Diabetes Mellitus, Chronic Disease
Interventions
Text Messaging (TM), Health Coaching (HC), Enhanced Usual Care (EC)
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
646 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
19
States / cities
Holly Springs, Mississippi • Bartlett, Tennessee • Covington, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nutrigenomics: Personalizing Weight Loss for Obese Veterans

NCT01859403
View directory record Official record
Conditions
Obesity
Interventions
Personalized Genomics, Usual Care
Genetic
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Oct 19, 2026, 2:56 PM EDT
Terminated Not applicable Interventional

A Study of the Efficacy of ONS to Reduce Postoperative Complications Associated With Pancreatic Surgery

NCT03244683
View directory record Official record
Conditions
Pancreatic Cancer, Chronic Pancreatitis
Interventions
Ensure Surgical, Nutrition counseling, Low-intensity exercise therapy
Dietary Supplement · Other
Lead sponsor
Ohio State University
Other
Eligibility
40 Years to 89 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 19, 2026, 2:56 PM EDT
Completed Not applicable Interventional

Individualized Nutrition Therapy for Preventing or Delaying Onset of Type-2 Diabetes

NCT05161897
View directory record Official record
Conditions
PreDiabetes, Cardiovascular Diseases
Interventions
Individualized Nutrition Therapy
Other
Lead sponsor
George Mason University
Other
Eligibility
45 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 19, 2026, 2:56 PM EDT
Not listed Not applicable Interventional

Diet as Essential Therapy (DIET) for Inflammatory Bowel Disease

NCT03012542
View directory record Official record
Conditions
Crohn Disease
Interventions
Diet 1, Diet 2
Dietary Supplement
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Oct 19, 2026, 2:56 PM EDT