Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 26, 2026, 11:05 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 189 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Dietary energy restriction Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Age and Weight Loss on Inflammation and Iron Homeostasis

NCT01636635
View directory record Official record
Conditions
Obesity, Aging
Interventions
Calorie Restriction
Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2015 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Effect of Bariatric Surgery on Metabolism, the Metabolome and Microbiome in Patients With Type 2 Diabetes

NCT02762708
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Roux-en-Y Gastric Bypass (RYGB), Caloric Restriction, Exendin-9,39, Normal Saline
Procedure · Behavioral · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Sep 26, 2026, 11:05 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Postprandial Nutrient Homeostasis Before and After Weight Loss Induced by Low-calorie Diet or RYGB

NCT03091725
View directory record Official record
Conditions
Obesity
Interventions
Roux-en-Y gastric bypass surgery, Low-calorie diet
Procedure · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Older Men and Postmenopausal Women: A Randomized Controlled Study

NCT05031663
View directory record Official record
Conditions
Immune Response, Inflammation
Interventions
Almond group, Control Group
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
40 Years to 70 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MOVE UP Lifestyle Intervention for Caregivers

NCT03967912
View directory record Official record
Conditions
Body Weight, Healthy Diet, Physical Activity, Health Behavior, Healthy Aging
Interventions
MOVE UP
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intermittent Fasting, Caloric Restriction and Body Composition in Obese Men and Women

NCT02525419
View directory record Official record
Conditions
Weight Loss
Interventions
Weight Loss Phase, HP-IF, HH
Behavioral
Lead sponsor
Skidmore College
Other
Eligibility
30 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2015 · Synced Sep 26, 2026, 11:05 PM EDT
Active, not recruiting Not applicable Interventional

Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia

NCT06998238
View directory record Official record
Conditions
Overweight and Obesity, Hyperandrogenemia, Insulin Resistance
Interventions
Mediterranean-based, carbohydrate restricted, calorie reduced diet
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Personalized Nutrition Study

NCT04145466
View directory record Official record
Conditions
Weight Loss
Interventions
High-fat diet, High-carbohydrate diet
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 75 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 26, 2026, 11:05 PM EDT
Recruiting Not applicable Interventional

Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

NCT07524244
View directory record Official record
Conditions
Rheumatoid Arthritis (RA), Crohn's Disease (CD), Ulcerative Colitis (UC)
Interventions
Ketogenic diet, Carnivore (Lion) Diet
Behavioral
Lead sponsor
Fuller Research Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Safety and Efficacy of Low and High Carbohydrate Diets

NCT00143936
View directory record Official record
Conditions
Obesity
Interventions
Low- Carbohydrate -Atkins Diet, Low Calorie Diet
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 14, 2010 · Synced Sep 26, 2026, 11:05 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The CALERIE™ Legacy Study

NCT05651620
View directory record Official record
Conditions
Calorie Restriction
Interventions
Not listed
Lead sponsor
Tufts University
Other
Eligibility
33 Years to 70 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustainability of MOVE UP Lifestyle Intervention

NCT03963830
View directory record Official record
Conditions
Body Weight, Diet, Healthy, Physical Disability
Interventions
MOVE UP
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Sep 26, 2026, 11:05 PM EDT
Terminated Phase 3 Interventional Results available

Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS

NCT01482286
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Metformin, Dietary Restriction, Exercise Training
Drug · Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Sep 26, 2026, 11:05 PM EDT
Recruiting Phase 2 Interventional

Milk Thistle Clinical Trial in Pediatric NAFLD

NCT06477146
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease (NAFLD)
Interventions
Milk thistle (MT), Placebo, Lifestyle Modification, Fibroscan
Drug · Behavioral · Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
9 Years to 22 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional

The Healthy Eating Choices for Life Program

NCT01096719
View directory record Official record
Conditions
Obesity
Interventions
Standard Behavioral Weight Loss Intervention, Dietary Goal: Reduction in Energy Density of Dietary Intake, Dietary Goal: Reduction of Energy Intake
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
21 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 26, 2026, 11:05 PM EDT
Completed No phase listed Observational

Bariatric Surgery and Weight Loss on Energy Metabolism and Insulin Sensitivity

NCT00936130
View directory record Official record
Conditions
Obesity, Protein-energy; Imbalance, Insulin Sensitivity, Gastrointestinal Complication
Interventions
Laparoscopic Roux-en-Y gastric bypass, Laparoscopic gastric banding, Laparoscopic sleeve gastrectomy, Low Calorie Diet
Procedure · Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Phase 2 Interventional

Survival TRaining for ENhancing Total Health (STRENGTH)

NCT00068458
View directory record Official record
Conditions
Breast Cancer, Depression, Weight Changes
Interventions
Calcium-Rich Diet, Arm 2: Exercise + Calcium-Rich Diet, Exercise + Fruit & Vegetable, Low Fat + Calcium Diet
Dietary Supplement · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
4
States / cities
Durham, North Carolina • Goldsboro, North Carolina • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Outlooks by Restriction of Diet and Sleep

NCT02413866
View directory record Official record
Conditions
Weight
Interventions
Calorie restriction only, Sleep & calorie restriction
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
35 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional

Energy Balance Interventions for Colorectal Cancer Prevention

NCT00653484
View directory record Official record
Conditions
Colorectal Cancer, Obesity
Interventions
Physical Activity, Energy Restriction, Physical Activity and Energy Restriction
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Sep 26, 2026, 11:05 PM EDT
Recruiting Not applicable Interventional

Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

NCT06736028
View directory record Official record
Conditions
Obesity
Interventions
Diet Therapy, Calorie Restriction, Behavioral Support
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

STUDY: Effects of Potatoes in a Weight Loss Program

NCT01186393
View directory record Official record
Conditions
Obesity
Interventions
Control, Low Glycemic Index, High Glycemic Index
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
2
States / cities
Davis, California • Mather, California
Source: ClinicalTrials.gov public record
Updated May 17, 2015 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional

Metabolism of Low Carbohydrate and Ketogenic Diet

NCT05071287
View directory record Official record
Conditions
Diabetic Kidney Disease, Cognitive Function, Weight Loss, Diabetic Control, Type2 Diabetes
Interventions
mHealth + low-fat diet, mHealth + low-carb/ketogenic diet
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Sep 26, 2026, 11:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Time-restricted Eating on Nutrient Absorption in Healthy Adults

NCT04877262
View directory record Official record
Conditions
Digestibility
Interventions
weight maintenance diet (WMD)
Other
Lead sponsor
Florida State University
Other
Eligibility
20 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Sep 26, 2026, 11:05 PM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 26, 2026, 11:05 PM EDT