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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Digital Game Clear all
Recruiting Not applicable Interventional

Sensor-controlled Digital Game for Heart Failure Self-management: A Clinical Trial

NCT05056129
View directory record Official record
Conditions
Heart Failure
Interventions
Sensor-controlled digital game (SCDG), Sensor Only
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
45 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Pink Warrior-Support Group Toolkit for Breast Cancer Survivors

NCT02750241
View directory record Official record
Conditions
Breast Cancer, Physical Activity
Interventions
Active video game-based intervention, Pedometer
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Emotion Regulation Intervention for Early Adolescent Risk Prevention

NCT03430570
View directory record Official record
Conditions
Risk Behavior, Risk Reduction, Emotion Regulation
Interventions
Tablet TRAC Emotion Regulation Intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
12 Years to 14 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 5, 2019 · Synced Sep 10, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

Serious Gaming for Chemotherapy-induced Nausea and Vomiting

NCT05838638
View directory record Official record
Conditions
Neoplasms, Chemotherapy-induced Nausea and Vomiting
Interventions
eSSET-CINV
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
60 Years and older
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Miami, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piloting a Mobile Game for Behavioral Therapy

NCT04450641
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism
Interventions
GuessWhat Mobile Application
Other
Lead sponsor
Stanford University
Other
Eligibility
3 Years to 12 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prognosis--A Game-Based Intervention to Improve STEM Skills

NCT03416218
View directory record Official record
Conditions
Knowledge, Attitudes, Practice
Interventions
Prognosis
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
Not listed
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 10, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

BID LTM Digital Intervention in Aging

NCT06916221
View directory record Official record
Conditions
Long-Term Memory, Inhibitory Control, Mild Cognitive Impairment
Interventions
Long Term Memory, Worder
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Relationship Enhancement Digital Game

NCT07170553
View directory record Official record
Conditions
Parent-Child Relations, Parenting, Attachment Disorder
Interventions
Digital Game, Control
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
6 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Coral Gables, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing an Evidence-Based, Disseminable, Free Internet-Based Parenting Program

NCT05689736
View directory record Official record
Conditions
Parenting Practices
Interventions
Motivational Enhancement, Simplification, Gamification, Low Engagement Nudges, Essentials for Parenting Toddlers and Pre-schoolers (EFP)
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years to 99 Years
Enrollment
859 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Game Targeting Suicide Prevention in Adolescents Who Report Substance Misuse

NCT05517382
View directory record Official record
Conditions
Substance Misuse, Suicide
Interventions
supportED, Control
Other
Lead sponsor
Yale University
Other
Eligibility
13 Years to 19 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 10, 2026, 5:57 PM EDT
Active, not recruiting Not applicable Interventional

An Adjunct Study to Assess Guided ADHD Therapy for Managing the Extent and Severity of Symptoms

NCT05805176
View directory record Official record
Conditions
ADHD
Interventions
ADHD Therapy
Device
Lead sponsor
Lumos Labs, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
5
States / cities
Jacksonville, Florida • Lakeland, Florida • Rochester Hills, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive and Emotional Skills to Aid Smoking Prevention

NCT03058991
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
12 Years to 16 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 10, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

A Randomized Controlled Trial Testing a Digital, Gamified Early Intervention for Eating Disorders ("FlexED")

NCT07632248
View directory record Official record
Conditions
Eating Disorders, Body Image
Interventions
FlexED, Educational Control
Behavioral
Lead sponsor
Duke University
Other
Eligibility
15 Years to 25 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Training Resiliency in Youth (TRY) Study

NCT03429465
View directory record Official record
Conditions
Attention Concentration Difficulty, Depression, Anxiety
Interventions
EVO Cognitive Remediation Game
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Games to Help Canadian and U.S. Adults Identify COVID-19 and Vaccine Misinformation: Three Sequential Randomized Studies

NCT07758309
View directory record Official record
Conditions
COVID-19, Vaccine Hesitancy, Health Misinformation, Communication
Interventions
Gamified misinformation refutation quiz, Refutational text (active control)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
3,637 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

NCT06633978
View directory record Official record
Conditions
MCI, Aging
Interventions
MediTrain, wrist worn multi-sensor watches, Sleep monitor
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Passive VR Versus Active VR on Heat Pain Thresholds and Pressure Pain Thresholds

NCT05836649
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Oculus Go headset without active intervention, Oculus Go headset with active intervention, Oculus Go headset without immersive virtual reality experience, Oculus Go headset with immersive virtual reality experience
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults

NCT04534686
View directory record Official record
Conditions
Frail Older Adults
Interventions
CogXergaming, Matter of Balance Training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Software Treatment for Actively Reducing Severity of ADHD - Follow Up

NCT02828644
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
EVO
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
15
States / cities
Scottsdale, Arizona • Newport Beach, California • Sacramento, California + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 10, 2026, 5:57 PM EDT
Not yet recruiting Not applicable Interventional

Evaluating Efficacy of a Digital Game Therapeutic for Children With Autism

NCT06058104
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Charades based mobile digital therapeutic
Device
Lead sponsor
Stanford University
Other
Eligibility
3 Years to 12 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Child Dietary Self-monitoring

NCT06193967
View directory record Official record
Conditions
Nutrition, Healthy
Interventions
Caregiver Praise, Gamification
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
8 Years to 100 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Group Digital Gaming: Experiences of Older Adults Living With Dementia in an Activity for Cognitive Impairment

NCT07541144
View directory record Official record
Conditions
Dementia
Interventions
Group-Based Digital Gaming
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Step Up for STEM and Health Careers

NCT06445751
View directory record Official record
Conditions
Adolescent Behavior
Interventions
Step Up for STEM and Health Careers ("Step Up") game, Educational PowerPoint Presentation on Diversity in STEM Careers
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
13 Years to 19 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs

NCT01808066
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Pervasive Developmental Disorder, Asperger's Disorder
Interventions
Groundskeeper
Device
Lead sponsor
CogCubed, Corp
Industry
Eligibility
5 Years to 12 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Sep 10, 2026, 5:57 PM EDT