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ClinicalTrials.gov public records Last synced Nov 8, 2026, 8:47 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Digital Navigation Clear all

Conditions: Loneliness, Opioid Use
Interventions: Cognitive Behavior Therapy (CBT), Social Navigation Group, Controlled Group; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Readmission, Readmission Rates, Readmission, Hospital, Elderly (People Aged 65 or More)
Interventions: Digital nudge prompting; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 65 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: COVID-19 Testing
Interventions: Navigation Services, Critical Dialogue, Brief Counseling, Referral and Digital Brochure; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years and older
Enrollment: 668 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Obesity
Interventions: Health Literacy and Culturally Tailored Materials, Community-Engaged Health Coaching and Navigation, Self-Monitoring and Remote Patient Monitoring of weight and physical activity, Community Asset Mapping (CAM), Primary Care Provider Training, Obesity Toolkit for Primary Care Providers; Behavioral · Other
Lead sponsor: Tulane University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 522 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 18
States / cities: Avondale, Louisiana • Bastrop, Louisiana • Baton Rouge, Louisiana + 15 more

Conditions: HIV Pre-Exposure Prophylaxis
Interventions: PrEP Navigation Services, Telehealth PrEP Services Referral, HealthMpowerment Digital Health Intervention - Enhanced, HealthMpowerment Digital Health Intervention - Basic; Other · Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 39 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Family Navigator Plus, Civic Engagement Plus
Interventions: Family Navigation, Civic Engagement Plus; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Nicotine Vaping, Nicotine Use Disorder
Interventions: quitSTART Mobile Application, Chatbot Feature in quitSTART Mobile Application; Device · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 15 Years to 25 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Type 2 Diabetes
Interventions: Digital Navigation; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Suicide Prevention, Suicide Safety Planning, Suicidal Ideation, Suicide Attempt
Interventions: Local Care Continuity, Centralized Care Navigation; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 176,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Pleasanton, California

Conditions: Lung Cancer
Interventions: Text Messages (TM+), Chat bot (CA), Video, Reactive Patient Navigation (RPN), Proactive Patient Navigation (PPN); Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 50 Years to 80 Years
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Alzheimer Disease, Dementia, Caregiver Burden, Financial Stress
Interventions: CONFIDENCE-AI; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pediatric Cancer, Pediatric ALL, Pediatric Brain Tumor, Attention Difficulties, Cognitive Deficit in Attention
Interventions: EndeavorRx, Control video game; Device · Other
Lead sponsor: Children's National Research Institute; Other
Eligibility: 8 Years to 16 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Breast Cancer Screening, Cervical Cancer Screening, Colon Cancer Screening, Tobacco Cessation
Interventions: Tools and Training for Cancer Control, Enhancing Social Capital and Civic Engagement; Behavioral
Lead sponsor: Harvard School of Public Health (HSPH); Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Boston, Massachusetts • Springfield, Massachusetts

Conditions: Prostate Carcinoma
Interventions: Educational Intervention, digital rectal examination, Pre-test administration, Survey Administration, Prostate-specific antigen measurement, Post test administration; Other · Procedure
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 19 Years and older · Male only
Enrollment: 319 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Familial Hypercholesterolemia
Interventions: Cascade Screening; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cancer, Health Care Utilization
Interventions: C4 Program; Other
Lead sponsor: Timothy Mullett; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Interventions: Survey Administration, Interview, Text Message-Based Navigation Intervention; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pregnancy Related
Interventions: OPTIMIZE; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 15 Years to 45 Years · Female only
Enrollment: 548 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Testicular Cancer
Interventions: Goal-focused Emotion-regulation Therapy; Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 39 Years · Male only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Irvine, California

Conditions: Alzheimer's Disease and Related Dementia
Interventions: DERA Online Training Program; Behavioral
Lead sponsor: George Mason University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Maternal Health, Pregnant Women
Interventions: WeCAB Intervention; Behavioral
Lead sponsor: State University of New York - Downstate Medical Center; Other
Eligibility: 18 Years to 49 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: COVID-19
Interventions: Navigation Services, Brief Counseling, Critical Dialogue, Referral and Digital Brochure; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years and older
Enrollment: 554 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: East Saint Louis, Illinois

Conditions: Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions: Culturally-tailored, enhanced adaption of Diabetes Prevention Program; Behavioral
Lead sponsor: University of Missouri, Kansas City; Other
Eligibility: 18 Years and older
Enrollment: 408 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Substance Related Disorders
Interventions: Just Care for Families (JCFF), Just Care for Families (JCFF) App, Just Care for Families (JCFF) App Feedback; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: Not listed
Enrollment: 254 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Eugene, Oregon

Search by objective public record fields.

Decreasing Loneliness to Optimize Pain Care

A Clinician-Patient Dual Behavior Change Framework to Leverage Informed Digital Nudges to Reduce Hospital Readmissions and Improve Patient Outcomes: A Trial for Scalable Strategy to Reduce Readmissions (PREVENT-R)

Optimization of a New Adaptive Intervention to Increase COVID-19 Testing

Collaborative Multi-level Obesity Intervention Engaging Communities Trial

Supporting Tailored And Responsive PrEP in Rural North Carolina

Building Capacity for Youth Mental Wellness: Family Navigator Model for Foster Parents

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

Digital Health Navigation for Latino Patients With Type II Diabetes

Suicide Safety Planning

Digital Health Implementation Strategies to Improve Lung Cancer Screening Among Safety-Net Clinics

CONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI)

Feasibility/Acceptability of Attentional-Control Training in Survivors

Community Gateway to Health Study

Informed Decision Making Intervention in Screening for Prostate Cancer of Predominantly African American Participants in a Community Outreach Program

Penn Family Screening for Familial Hypercholesterolemia (NHLBI R33) Trial 3

Comprehensive Connected Cancer Care (C4): Intervention Evaluation

Digital Meditation for Postoperative Pain Control After Abdominal Surgery for Cancer

The OPTIMIZE Study: Optimizing Patient Navigation for Perinatal Care

Young Adult Latino Testicular Cancer Survivors: a Pilot Study of Goal-Focused Emotion Regulation Therapy (GET)

Randomized Controlld Trial of Dementia Education Resources for Action

We Care About Brooklyn - A Digital Behavioral Intervention to Optimize Engagement in Maternal Healthcare

COVID-19 Treatment Cascade Optimization Study

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

Testing Implementation Strategies to Scale-up a Multicomponent Continuum of Service Intervention for Families Involved in Systems With Parental Opioid and Methamphetamine Use