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Showing 1–24 of 60 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Digital weight loss intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care

NCT03003403
View directory record Official record
Conditions
Obesity, Overweight, Overnutrition, Nutrition Disorders, Signs and Symptoms
Interventions
Intervention Program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 13, 2026, 5:17 AM EDT
Active, not recruiting Not applicable Interventional

Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology

NCT05523375
View directory record Official record
Conditions
Obesity, Diabetes Mellitus, Type 2, PreDiabetes
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
40 Years to 70 Years
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Families on Track: A Digital Health Behavioral Intervention for Parents Seeking Treatment for Their Child With Obesity

NCT02767440
View directory record Official record
Conditions
Obesity, Childhood Obesity, Hypertension, Diabetes, Dyslipidemia
Interventions
Families on Track Intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, NC, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2017 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Phase 2 Interventional

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

NCT07228741
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Obesity
Interventions
Tirzepatide, Resistance Exercise, Lifestyle Counseling
Drug · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Delicious Eating for Life in Southern Homes

NCT04302727
View directory record Official record
Conditions
Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
Interventions
Med-South Weight Loss Intervention, WW
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional

Lifestyle Change Implementation Research Network at PRC at UMass Chan

NCT07481305
View directory record Official record
Conditions
GLP - 1
Interventions
Digital Lifestyle Coaching Program
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Stepped Care for Weight Loss Maintenance

NCT06151145
View directory record Official record
Conditions
Obesity
Interventions
Usual care, SELF, STEP
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Terminated Not applicable Interventional Results available

PDA+: A Personal Digital Assistant for Obesity Treatment

NCT00371462
View directory record Official record
Conditions
Obesity, Pain
Interventions
Use of PDA + support to reduce weight and pain, MOVE! level 2 group weight loss counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional

Avoiding Diabetes After Pregnancy Trial

NCT01923350
View directory record Official record
Conditions
Weight Reduction
Interventions
Weight Reduction Intervention, Weight Reduction Control Arm, Tested for diabetes, Not tested for diabetes
Behavioral
Lead sponsor
Social & Scientific Systems Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 14, 2013 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional Results available

The Healthy Moms Study: Comparison of a Post-Partum Weight Loss Intervention Delivered Via Facebook or In-Person Groups

NCT03700736
View directory record Official record
Conditions
Weight Loss, Diet Modification, Physical Activity
Interventions
Healthy Moms
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional

Redefining BMI: The Body, Mind, and Inflammation Trial

NCT06532747
View directory record Official record
Conditions
Obesity, Adiposity
Interventions
Integrated Lifestyle Intervention (ILI), Monitoring with digital tools
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional

TREC Lifestyle Beyond Cancer Study in Endometrial Cancer Survivors

NCT02466061
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Telemedicine Weight Management plus Wi-Fi Scale (Arm A), Text for Diet (Text4Diet) Group (Arm B), Enhanced Usual Care Group (Arm C)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2016 · Synced Sep 13, 2026, 5:17 AM EDT
Active, not recruiting Phase 2 Interventional

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

NCT04742751
View directory record Official record
Conditions
PreDiabetes, Adult Children
Interventions
Metformin, Digital Intervention
Drug · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 44 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional

ClockWork Postpartum Weight Management Study

NCT04992637
View directory record Official record
Conditions
Obesity, Postpartum Weight Retention, Weight Gain, Maternal
Interventions
ClockWork, Usual Care
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RESILIENCE: Personalizing Cardiovascular Health

NCT04551872
View directory record Official record
Conditions
Obesity, Cardiovascular Risk Factor
Interventions
Digital weight loss intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
40 Years to 75 Years
Enrollment
598 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Charge: A Text Messaging-based Weight Loss Intervention

NCT03254940
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Charge
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
534 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 13, 2026, 5:17 AM EDT
Not yet recruiting Not applicable Interventional

Simplifying Diet Tracking in a Digital Weight Loss Intervention

NCT07601061
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions
Simplified Dietary Self-Monitoring, Detailed Dietary Self-Monitoring, Core Behavioral Weight Loss Intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining Valence-based Effects in Self-Monitoring Feedback Messages

NCT07292389
View directory record Official record
Conditions
Obesity & Overweight, Obesity (Disorder)
Interventions
Positive Reinforcement, Positive Reinforcement + Areas for Change
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional

Collaborative Multi-level Obesity Intervention Engaging Communities Trial

NCT06835686
View directory record Official record
Conditions
Obesity
Interventions
Health Literacy and Culturally Tailored Materials, Community-Engaged Health Coaching and Navigation, Self-Monitoring and Remote Patient Monitoring of weight and physical activity, Community Asset Mapping (CAM), Primary Care Provider Training, Obesity Toolkit for Primary Care Providers
Behavioral · Other
Lead sponsor
Tulane University
Other
Eligibility
18 Years to 75 Years
Enrollment
522 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
18
States / cities
Avondale, Louisiana • Bastrop, Louisiana • Baton Rouge, Louisiana + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

NCT05301413
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity
Interventions
Culturally Tailored Diabetes Prevention Program, Culturally Tailored DPP Enhanced with Socioeconomic Supports, Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Sep 13, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional

Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older

NCT06636058
View directory record Official record
Conditions
Obesity, Depression
Interventions
vCare Intervention (6-month active treatment followed by 6-month maintenance), vCare Intervention (active treatment after 6 months)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 74 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 13, 2026, 5:17 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of a Technology-Based Intervention on Weight Change Post-Bariatric Surgery

NCT02867696
View directory record Official record
Conditions
Motor Activity, Weight Loss
Interventions
Standard Care, Technology-based Intervention (TECH)
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Sep 13, 2026, 5:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Exercise, and Technology for Weight Loss

NCT02731768
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard, Social support-enhanced, Fitbit Zip, Digital body weight scale
Behavioral · Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 13, 2026, 5:17 AM EDT