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ClinicalTrials.gov public records Last synced Sep 5, 2026, 11:46 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Dim Light Clear all
Completed Phase 3 Interventional Results available

Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial

NCT00852592
View directory record Official record
Conditions
Bipolar Disorder, Major Depressive Episode
Interventions
7000lux broad-spectrum light, 50lux dim red light
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2016 · Synced Sep 5, 2026, 11:46 PM EDT
Active, not recruiting Not applicable Interventional

Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease

NCT02909192
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Light Therapy Device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

Morning Light Treatment at Home to Reduce PTSD Symptoms

NCT03513848
View directory record Official record
Conditions
PTSD
Interventions
Retimer, Retimer placebo
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Phase 4 Interventional Results available

Symfony vs Vivity in Dim Light

NCT06229106
View directory record Official record
Conditions
Cataract
Interventions
Symfony IOL, Vivity IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sarasota, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

SCREENS: Sleep, Circadian Rhythms, and Electronics in the EveNing Study

NCT06192745
View directory record Official record
Conditions
Sleep, Circadian Rhythm, Executive Function, Emotion Regulation
Interventions
no screen control with dim light and calming activities, unfiltered Bright tablet screen, Filtered dim tablet screen, Exciting content, Calming Content
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 11 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors

NCT02954809
View directory record Official record
Conditions
Fatigue, Sleep Disturbance, Circadian Dysregulation
Interventions
Morning bright light therapy, Dim light
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

Smart Lighting for Nursing Home Residents With Dementia

NCT05825404
View directory record Official record
Conditions
Alzheimer's Disease and Related Dementias
Interventions
Smart Ambient Bright Light (SABL), Control
Device · Other
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Belleville, Pennsylvania • DuBois, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study

NCT03122236
View directory record Official record
Conditions
Mobility Limitation, Cognitive Impairment
Interventions
Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Sham Transcranial Direct Current Stimulation (Sham tDCS), Active Transcranial Direct Current Stimulation (Active tDCS)
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 110 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

Light Therapy Treatment in Parkinson's Disease Patients With Daytime Somnolence

NCT01338649
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disorder; Excessive Somnolence
Interventions
Bright Light Treatment (Sun Ray Sunbox SB-558), Dim red light (Sun Ray Sunbox SB-558)
Device
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 5, 2026, 11:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Noradrenergic Dysregulation, Sleep and Cognition in Older Adults With Insomnia

NCT06694441
View directory record Official record
Conditions
Insomnia
Interventions
Light Exposure, Placebo
Other
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet

NCT03802721
View directory record Official record
Conditions
Environmental Exposure
Interventions
[14C]-benzo[a]pyrene, Brussels sprouts before 50 ng dose, DIM supplement before 50 ng dose
Drug
Lead sponsor
Oregon State University
Other
Eligibility
21 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

Light Treatment to Improve Symptom Management of Fibromyalgia Syndrome

NCT03794908
View directory record Official record
Conditions
Fibromyalgia, FMS
Interventions
Light therapy A (Bright) via the Re-Timer®, Light therapy B (Dim) via the Re-Timer®
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 5, 2026, 11:46 PM EDT
Recruiting Not applicable Interventional

Systematic Light Exposure in Pediatric Brain Tumor Survivors

NCT05340881
View directory record Official record
Conditions
Brain Tumor
Interventions
Bright Light Exposure, Dim Light Exposure, Cognitive Assessment
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Light Therapy for Fatigue N-of-1 Trials

NCT04707846
View directory record Official record
Conditions
Fatigue
Interventions
Bright Blue Light Commercial AYO Light Therapy Device, Dim Blue Light Commercial AYO Light Therapy Device
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Individually Tailored Lighting System to Improve Sleep in Older Adults

NCT01855126
View directory record Official record
Conditions
Sleep Disturbances
Interventions
Blue light, Red light
Other
Lead sponsor
Rensselaer Polytechnic Institute
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Troy, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Phase 3 Interventional Results available

The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder

NCT03715465
View directory record Official record
Conditions
Delayed Sleep Phase Syndrome
Interventions
Melatonin 0.5 MG, Dim Light Melatonin Onset (salivary)
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional

Laser Acupuncture Before and After Embryo Transfer Improves IVF Outcomes

NCT02815371
View directory record Official record
Conditions
Embryo Implantation
Interventions
Needle Acupuncture, Laser Acupuncture, Sham Laser Acupuncture
Procedure
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Norwalk, Connecticut • Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease

NCT00946530
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Bright light, Control
Device
Lead sponsor
Stanford University
Other
Eligibility
55 Years to 100 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Sep 5, 2026, 11:46 PM EDT
Recruiting No phase listed Observational

Clinical Evaluation of WaveLight Plus LASIK

NCT07127757
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Wavelight Plus LASIK
Device
Lead sponsor
Laser Defined Vision
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed No phase listed Observational

Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU

NCT03313115
View directory record Official record
Conditions
Sleep Deprivation, Delirium
Interventions
Sleep/Wake Protocol
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
685 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional

Pilot Comparison of N-of-1 Trials of Light Therapy

NCT03167372
View directory record Official record
Conditions
Cancer, Health Behavior, Depression
Interventions
Litebook® Advantage, Fitbit Flex2 TM
Other
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction

NCT04868539
View directory record Official record
Conditions
Glucose Intolerance, Sleep Deprivation, Sleep
Interventions
Sleep Restriction with ALAN first, then Sleep Restriction without ALAN, Sleep Restriction without ALAN first, then sleep restriction with ALAN
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 5, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

Effect of Increased Light Exposure on Fatigue in Breast Cancer

NCT00478257
View directory record Official record
Conditions
Breast Cancer
Interventions
bright white light, comparator red light treatment
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Sep 5, 2026, 11:46 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders

NCT00387179
View directory record Official record
Conditions
Sleep Disorders, Circadian Rhythm
Interventions
Melatonin, Methylxanthine, Light Therapy
Drug · Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 24, 2009 · Synced Sep 5, 2026, 11:46 PM EDT