Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:22 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 95 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Diode Laser Treatment Clear all

Conditions: Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
Interventions: Real LED Intervention, Sham LED Intervention; Device
Lead sponsor: Boston VA Research Institute, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lipolysis
Interventions: 950 nm LED Device, 1050nm Diode Laser Device; Device
Lead sponsor: Venus Concept; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative, Suppuration of Gingival Crevice
Interventions: Scaling and Root Planing, Diode Laser + Scaling and Root Planing; Procedure
Lead sponsor: University of Nebraska; Other
Eligibility: 30 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Retinopathy of Prematurity
Interventions: Ranibizumab, Laser therapy; Drug · Procedure
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: Not listed
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 12
States / cities: Loma Linda, California • Sacramento, California • Aurora, Colorado + 9 more

Conditions: Melasma
Interventions: Tranexamic Acid; Drug
Lead sponsor: Laser and Skin Surgery Center of New York; Other
Eligibility: 18 Years to 50 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: New York, New York • Houston, Texas

Conditions: Neuropathic Pain, Sensation Disorders
Interventions: PBM light therapy; Device
Lead sponsor: Tufts University; Other
Eligibility: 18 Years to 65 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Pain Related to TMD
Interventions: THOR® laser system, sham THOR® laser system; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Photoaging
Interventions: CLEAR + BRILLIANT TOUCH(R) 1440-nm and 1927-nm handpieces.; Device
Lead sponsor: Bausch Health Americas, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Chronic Venous Insufficiency
Interventions: Ablation of the incompetent small saphenous vein; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2017
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Wound Heal
Interventions: Celluma POD; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Irvine, California

Conditions: Skin Ageing, Facial Wrinkles, Acne, Skin Elasticity, Infraorbital Dark Circle Severity, Skin Firmness, UV Spots, Skin Texture, Skin Pores, Brown Spots, Porphyrins, Red Spots
Interventions: NIRA Laser M2.1, Topical; Device · Other
Lead sponsor: NIRA Innovations Inc.; Industry
Eligibility: 35 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Beverly, Massachusetts

Conditions: Tinnitus
Interventions: Erchonia Hearing Lasers #1 & #2, Placebo Lasers; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Periodontal Diseases
Interventions: mechanical debridement, adjunctive aPDT, sham aPDT; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Circumference Reduction
Interventions: Erchonia Violet Zerona Z6; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Bloomfield Hills, Michigan • Marquette, Michigan

Conditions: Chronic Venous Insufficiency
Interventions: Ablation of the Incompetent Greater Saphenous Vein, ClosureFAST radiofrequency catheter, EVLT 980nm diode laser system; Procedure · Device
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2016
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Overweight, Obese
Interventions: LLLT, Lorcaserin; Device · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cellulite
Interventions: Erchonia Scanner device (GLS), Placebo device; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Marion, Indiana • Bloomfield Hills, Michigan

Conditions: Hypertrichosis
Interventions: Soprano/SHR, LightSheer; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Irvine, California

Conditions: Thyroid Nodule, Thyroid Cancer, Thyroid Neoplasms, Nodular Goiter
Interventions: Laser Ablation of Thyroid Nodule; Procedure
Lead sponsor: BioTex, Inc.; Industry
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: TMJ, TMJ Pain, TMD
Interventions: Erchonia® EVRL™, Placebo Device; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 22 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Acton, Massachusetts

Conditions: Neuropathy, Diabetic, Neuropathy;Peripheral, Neuropathy, Painful
Interventions: Erchonia® EVRL™, Placebo Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 4
States / cities: Phoenix, Arizona • West Covina, California • Dunedin, Florida + 1 more

Conditions: Cognitive Aging, Alzheimer Disease, Protection Against
Interventions: Active NIR-PBM, Sham NIR-PBM; Device
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 89 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 2
States / cities: Tucson, Arizona • Gainesville, Florida

Conditions: Onychomycosis
Interventions: Erchonia FX-405™ Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Chronic Periodontitis
Interventions: Epic Diode, HP, Sham; Device · Drug
Lead sponsor: Biolase Inc; Industry
Eligibility: 30 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: San Mateo, California

Search by objective public record fields.

Photobiomodulation to Improve Cognition in TBI, With fMRI

LED Device for Non-Invasive Lipolysis

Diode Laser Study for Periodontal Maintenance Patients

RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity

Oral Tranexamic Acid and Laser for Treatment of Melasma

Photobiomodulation on Neuropathic Pain and Sensation Post-mastectomy

Photobiomodulation for the Management of Temporomandibular Disorder Pain

Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelength Treatment

Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein

Effect of Combined Red and Near Infrared Light-emitting Diode (LED) Therapy on Tissue Regeneration Post Laser Treatment

Clinical Study Evaluating the Safety and Effectiveness of the NIRA Laser M2.1 for the Treatment of Full-Face Wrinkles

Study of Low Level Laser Therapy and Tinnitus Relief

Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease

An Evaluation of the Effect of the Erchonia Corporation Violet Zerona® Z6 for Body Contouring

Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein

Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management

Study of the Effect of Low Level Laser Light Therapy on Reducing the Appearance of Cellulite in the Thighs and Buttocks.

Comparison of Efficacy, Safety and Tolerability of Two Different 810 nm Diode Lasers for Hair Reduction

Pilot Study on Laser Ablation of Symptomatic Benign Thyroid Masses

Evaluation of the Effect of the Erchonia® EVRL on Chronic Jaw Pain Arising From TMJ

Clinical Efficacy and Human Factors Validation Testing of the Erchonia EVRL for Providing Temporary Relief of Diabetic Peripheral Neuropathy Foot Pain

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

Study of the Use of Low Level Laser Light Therapy to Treat Toenail Fungus

Perio. Maint. With Diode LBR