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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Direct Laryngoscopy Clear all
Completed Phase 4 Interventional Results available

Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management

NCT01710891
View directory record Official record
Conditions
Acute Respiratory Distress
Interventions
CMAC videolaryngoscope, Direct Laryngoscopy
Procedure
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion

NCT05770518
View directory record Official record
Conditions
Paradoxical Vocal Fold Motion, Vocal Cord Dysfunction
Interventions
Biofeedback, Laryngeal control therapy (LCT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study

NCT02051816
View directory record Official record
Conditions
Respiratory Failure
Interventions
Video Laryngoscopy, Apneic Oxygenation, Direct Laryngoscopy, No Apneic Oxygenation
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of Endotracheal Intubation Using Glidescope Video-Laryngoscope

NCT01683526
View directory record Official record
Conditions
Respiratory Failure
Interventions
Direct laryngoscopy, Video laryngoscopy (Glidescope)
Procedure · Device
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2014 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Human Laryngeal Evoked Brainstem Potentials

NCT02803359
View directory record Official record
Conditions
Thyroidectomy
Interventions
Placement of a needle electrode through the thyrohyoid membrane into the submucosal space within the false vocal fold
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Sep 3, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional

Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration

NCT07426016
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Surfactant Deficiency Syndrome Neonatal
Interventions
Video Laryngoscopy, Direct Laryngoscopy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
0 Hours to 3 Days
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 3, 2026, 7:05 PM EDT
Withdrawn Phase 3 Interventional

Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?

NCT01248234
View directory record Official record
Conditions
Hypertension
Interventions
propofol, Etomidate, Propofol and Etomidate
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
65 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 15, 2012 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

KingVision Video Laryngoscopy vs Direct Laryngoscopy - Equivalence Trial

NCT02590237
View directory record Official record
Conditions
Tracheal Intubation
Interventions
Ambu KingVision Video Laryngoscope aBlade, Miller Direct Laryngoscopy
Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 2 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2016 · Synced Sep 3, 2026, 7:05 PM EDT
Terminated Not applicable Interventional Results available

Comparison of Direct Laryngoscopy, Truview EVO2 and Glidescope in Pediatric Patients

NCT01023568
View directory record Official record
Conditions
Intubation
Interventions
Macintosh blade, Glidescope, Truview PCD
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Up to 10 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Cervical Spine Biomechanics During Endotracheal Intubation

NCT01369381
View directory record Official record
Conditions
Spinal Diseases, Other Biomechanical Lesions of Cervical Region, Tracheal Intubation Morbidity
Interventions
Endotracheal intubation
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 6, 2012 · Synced Sep 3, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional

Force Sensor Study

NCT07434583
View directory record Official record
Conditions
Laryngeal Disease, Post-operative Pain, Tongue Injury
Interventions
Direct laryngoscopy force modulation, Direct laryngoscopy without force modulation
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

VL vs DL in Inexperienced Users: a Pediatric Manikin Study

NCT02991820
View directory record Official record
Conditions
Videolaryngoscopes (VL), Direct Laryngoscopy (DL), Inexperienced Users
Interventions
Miller, Macintosh, C-MAC, GlideScope
Device
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Not listed
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Nasotracheal Intubation With VL vs DL in Infants Trial

NCT05433155
View directory record Official record
Conditions
Intubation Complication, Intubation; Difficult or Failed, Hypoxia, Hypoxemia, Anesthesia Intubation Complication, Pediatric HD
Interventions
Nasotracheal intubation
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Day to 365 Days
Enrollment
680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Aurora, Colorado • Washington D.C., District of Columbia • Philadelphia, Pennsylvania + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 3, 2026, 7:05 PM EDT
Recruiting Phase 1 Interventional

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

NCT06747390
View directory record Official record
Conditions
Oropharyngeal Squamous Cell Carcinoma (OPSCCA), Oropharyngeal Cancer, Human Papilloma Virus, Squamous Cell Carcinoma
Interventions
Lidocaine 1% Injectable Solution
Drug
Lead sponsor
Ryan Carey
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional

"Just-In-Time Training" in Pediatric Airway Management

NCT00631176
View directory record Official record
Conditions
Orotracheal Intubation
Interventions
Just-In-Time Training
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 7, 2010 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

General Anesthesia With ETT vs LMA in Patients Undergoing Ablation for Atrial Fibrillation

NCT02896595
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
General Anesthesia with endotracheal tube, General Anesthesia with laryngeal mask airway
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

The Use of the GlideScope Ranger in Pediatric Critical Care Transport

NCT01054183
View directory record Official record
Conditions
Respiratory Failure
Interventions
GlideScope Ranger Intubation, Direct Laryngoscopy
Device
Lead sponsor
Akron Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2015 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

McGRATH MAC Video Laryngoscope

NCT02250521
View directory record Official record
Conditions
Intubation; Difficult
Interventions
McGrath MAC enhanced direct laryngoscope
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Initial Experience With Storz C-MAC Video Intubation System

NCT01104090
View directory record Official record
Conditions
Intubation; Difficult
Interventions
C-MAC direct laryngoscopy, C-MAC Indirect laryngoscopy
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 3, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional

Limiting Emergence Phenomena After General Anesthesia With Combined LMA and ETT Airway Management Technique

NCT02708836
View directory record Official record
Conditions
Limit Emergence Phenomena After General Anesthesia
Interventions
Induction of anesthesia, Placement of LMA [Ambu (R) AuraGain (TM) disposable laryngeal mask], Laryngoscopy and placement of ETT, Ventilation via the ETT, Removal of the ETT, Intubation of the trachea through the LMA, Ventilation via the LMA, Emergence from anesthesia
Procedure · Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 3, 2026, 7:05 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Video vs. Direct Laryngoscopy in Pediatric Nasal Intubation

NCT03032263
View directory record Official record
Conditions
Nasal Intubation
Interventions
Video Laryngoscopy for nasal intubation, Direct Laryngoscopy
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
3 Years to 14 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

DirEct Versus VIdeo LaryngosCopE Trial

NCT05239195
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Video Laryngoscope, Direct Laryngoscope
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
12
States / cities
Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 3, 2026, 7:05 PM EDT
Not listed Not applicable Interventional

Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation

NCT03775317
View directory record Official record
Conditions
Intubation, Intratracheal
Interventions
Video Laryngoscopy, Direct Laryngoscopy
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Sep 3, 2026, 7:05 PM EDT
Completed Not applicable Interventional

LISA in the Delivery Room for Extremely Preterm Infants

NCT04715373
View directory record Official record
Conditions
Extreme Prematurity, Respiratory Distress Syndrome
Interventions
LISA
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
5 Minutes to 20 Minutes
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 3, 2026, 7:05 PM EDT