- Conditions
- Penicillin Allergy
- Interventions
- Penicillin Major Determinant (PrePen) Skin Testing, Direct Oral challenge
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 284 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 2
- States / cities
- New Orleans, Louisiana • Seattle, Washington
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- Conditions
- Penicillin Allergy
- Interventions
- Amoxicillin 250 MG, Placebo, Amoxicillin 62.5mg, Amoxicillin 187.5mg
- Drug
- Lead sponsor
- James Tarbox, MD
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 380 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- Penicillin Allergy
- Interventions
- Amoxicillin
- Drug
- Lead sponsor
- Geisinger Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 4
- States / cities
- Danville, Pennsylvania • Lewiston, Pennsylvania • Scranton, Pennsylvania + 1 more
- Conditions
- Penicillin, Drug Allergy
- Interventions
- Direct Oral Challenge
- Procedure
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 2 Years to 30 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Hypersensitivity, Immediate, Hypersensitivity, Delayed, Hypersensitivity Response
- Interventions
- Direct oral penicillin challenge, Standard of care
- Other
- Lead sponsor
- Austin Health
- Government
- Eligibility
- 18 Years and older
- Enrollment
- 382 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Nashville, Tennessee