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ClinicalTrials.gov public records Last synced Oct 26, 2026, 9:49 PM EDT

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Showing 73–96 of 626 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Direct tDCS Clear all
Completed Not applicable Interventional Results available

Self Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

NCT03425019
View directory record Official record
Conditions
Knee Osteoarthritis, Chronic Pain
Interventions
Soterix 1x1 tDCS mini-CT Stimulator device
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2021 · Synced Oct 26, 2026, 9:49 PM EDT
Terminated Not applicable Interventional Results available

Augmenting Exposure Therapy for Social Anxiety With Transcranial Direct Current Stimulation

NCT03743571
View directory record Official record
Conditions
Social Anxiety
Interventions
transcranial direct current stimulation, exposure therapy
Device · Behavioral
Lead sponsor
University of Nevada, Reno
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Active, not recruiting Not applicable Interventional

Targeted HD-tDCS to Improve Upper Limb Rehabilitation in SCI

NCT05589415
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
High-definition Transcranial Direct Current Stimulation, Conventional Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Texas Rio Grande Valley
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Harlingen, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Not yet recruiting Not applicable Interventional

Neuromodulation for Patients With Parkinson's Disease

NCT07767006
View directory record Official record
Conditions
Adults With Parkinson's Disease
Interventions
tDCS combined with TUS
Device
Lead sponsor
Felipe Fregni, MD, PhD, MPH
Other
Eligibility
40 Years to 85 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Not applicable Interventional Results available

Remediation of Auditory Recognition in Schizophrenia With tDCS

NCT02869334
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Active Transcranial direct current stimulation (tDCS), Sham Transcranial direct current stimulation (tDCS), Auditory Remediation, Control computer activities
Device · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Pre-Frontal tDCS on Sleep Propensity During an Afternoon Nap: RCT

NCT02176785
View directory record Official record
Conditions
Sleep
Interventions
transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Not applicable Interventional

NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery

NCT02020421
View directory record Official record
Conditions
Aphasia
Interventions
rTMS, tDCS, Sham rTMS, Sham tDCS
Device
Lead sponsor
Dr. Alexander Thiel
Individual
Eligibility
50 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Not applicable Interventional Results available

Targeted High-definition Transcranial Direct Current Stimulation (HD-tDCS) for Reducing Post-stroke Movement Impairments

NCT05174949
View directory record Official record
Conditions
Stroke
Interventions
Transcranial direct current stimulation (high-definition)
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Phase 2 Interventional

TDCS to Reduce Craving in Cocaine Addiction- Phase 2 Study

NCT04994821
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
transcranial direct current stimulator (tDCS), Cognitive Reappraisal
Device · Behavioral
Lead sponsor
Soterix Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 26, 2026, 9:49 PM EDT
Withdrawn Early Phase 1 Interventional

Transcranial Direct Current Stimulation in Reducing Pain in Cancer Patients With Chemotherapy Induced Peripheral Neuropathy

NCT04135326
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Malignant Neoplasm
Interventions
Quality-of-Life Assessment, Questionnaire Administration, Transcranial Direct Current Stimulation
Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 26, 2026, 9:49 PM EDT
Not yet recruiting Not applicable Interventional

Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing

NCT07787572
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
transcranial alternating current stimulation, sham transcranial alternating current stimulation, Motivational interviewing (MI)
Device · Behavioral
Lead sponsor
The Mind Research Network
Other
Eligibility
21 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain

NCT06132412
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
transcranial direct current stimulation, physical therapy
Device · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Recruiting Not applicable Interventional

Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter

NCT07354139
View directory record Official record
Conditions
Stuttering, Fluency Disorder
Interventions
High - Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Neurosensory Account of Anxiety and Stress (Study 2)

NCT07079839
View directory record Official record
Conditions
Threat-related Sensory Cortical (SC) Disinhibition, Posttraumatic Stress Disorder (PTSD)
Interventions
Transcranial Alternating Current Stimulation (tACS), Sham for Transcranial Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Not applicable Interventional

Targeted Noninvasive Brain Stimulation (T-NIBS) to Improve Hand Motor Functions in Acquired Brain Injury

NCT04057105
View directory record Official record
Conditions
Upper Extremity Dysfunction, Traumatic Brain Injury
Interventions
Active High-definition Transcranial Direct Current Stimulation (HD-tDCS), MusicGlove
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Completed Not applicable Interventional Results available

tDCS to Decrease Opioid Relapse (UG3)

NCT03842137
View directory record Official record
Conditions
Opioid Dependence, Craving
Interventions
tDCS, sham tDCS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
21 Years to 50 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 26, 2026, 9:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Tactile Learning in Stroke Patients

NCT00283881
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 26, 2026, 9:49 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm

NCT01201629
View directory record Official record
Conditions
Brain Infarction, Brain Ischemia
Interventions
t DC stimulation, tDCStimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 26, 2026, 9:49 PM EDT
Recruiting Not applicable Interventional

Optimization of NIBS for Treatment of Addiction

NCT04379115
View directory record Official record
Conditions
Opioid-use Disorder, Chronic Pain
Interventions
Active Comparator: Active tDCS + Active TUS, Sham Comparator: Sham tDCS + Sham TUS
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 85 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Hinsdale, Illinois • Cambridge, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Terminated Not applicable Interventional Results available

Non-invasive Brain Stimulation in Adults Who Stutter

NCT03437512
View directory record Official record
Conditions
Stuttering, Developmental
Interventions
Anodal tDCS, Fluency training, Sham tDCS
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 26, 2026, 9:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Electrical Stimulation to Enhance Recovery After Stroke

NCT00085657
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 26, 2026, 9:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multifocal HD-tDCS and Motor Function

NCT06561165
View directory record Official record
Conditions
Healthy
Interventions
Standard HD-tDCS intervention, Multifocal network targeted HD-tDCS intervention, Functional Magnetic Resonance Imaging (fMRI)
Device
Lead sponsor
University of Michigan
Other
Eligibility
65 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Recruiting Not applicable Interventional

tDCS for Laryngeal Dystonia

NCT06830174
View directory record Official record
Conditions
Laryngeal Dystonia
Interventions
Starstim system
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 26, 2026, 9:49 PM EDT
Terminated Not applicable Interventional

Effectiveness of Transcranial Direct Current Stimulation (tDCS).

NCT04902274
View directory record Official record
Conditions
Ankle Sprains, Musculoskeletal Injury
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, Physical Therapy
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Oct 26, 2026, 9:49 PM EDT