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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 75 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Direct to Patient Message Clear all
Recruiting Not applicable Interventional

Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)

NCT07337577
View directory record Official record
Conditions
Heart Failure
Interventions
LLM-GDMT Clinical Decision Support Tool
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients

NCT05021185
View directory record Official record
Conditions
Tobacco Dependence, Tobacco Use Cessation, Cancer
Interventions
Interactive Mobile Doctor (iMD)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trial of an Adolescent Male Sexual Health Intervention

NCT04969289
View directory record Official record
Conditions
Contraception Behavior
Interventions
Dr. Eric Digital Health Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
14 Years to 21 Years · Male only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

Determining the Preliminary Efficacy of the Emergency Department Delirium Screening and Detection Program

NCT05638945
View directory record Official record
Conditions
Delirium
Interventions
ED Delirium Screening and Detection Program (ED-DDP)
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
65 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Digital Health Implementation Strategies to Improve Lung Cancer Screening Among Safety-Net Clinics

NCT07716280
View directory record Official record
Conditions
Lung Cancer
Interventions
Text Messages (TM+), Chat bot (CA), Video, Reactive Patient Navigation (RPN), Proactive Patient Navigation (PPN)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
50 Years to 80 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional

Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)

NCT05743517
View directory record Official record
Conditions
Ovary Cancer, Endometrial Cancer, Uterine Cancer, Cervical Cancer, Cervix Cancer, Vulvar Cancer, Vaginal Cancer
Interventions
Fit4Treatment
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years and older · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM)

NCT02330419
View directory record Official record
Conditions
Binge Drinking, HIV
Interventions
Placebo, Naltrexone, Medical Management (MM) counseling for alcohol use:, Urinalysis for novel alcohol biochemical markers:, Behavioral survey measurements:, Dried Blood Spot (DSB) Testing for Phosphatidylethanol, Ecological Momentary Assessment
Drug · Behavioral · Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

Improving Follow-Up for Discharged Emergency Care Patients

NCT03002311
View directory record Official record
Conditions
General Medicine, Emergency Medicine, Mobile Health
Interventions
Epharmix/CareSignal eHealth
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
5 Years and older
Enrollment
327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 22, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional

Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening

NCT05693649
View directory record Official record
Conditions
Colorectal Cancer
Interventions
No Direct Patient Outreach, Direct Patient Outreach: Colonoscopy Only, Direct Patient Outreach: Sequential Choice, Visit-Based Nudge/Text, No Nudge/Text
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 72 Years
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional

Leveraging mHealth to Enable and Adapt CHW Strategies to Improve TB/HIV Patient Outcomes in SA

NCT04298905
View directory record Official record
Conditions
Adherence, Patient, TB, HIV/AIDS, Care Coordination
Interventions
CHW mHealth patient intervention for trigger escalation
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression

NCT06083987
View directory record Official record
Conditions
Anxiety, Depression, Adolescent Behavior, Sexual and Gender Minorities
Interventions
Intersectionality and Identity, Confidentiality, Educating Your Community, How to find Affirming Caregivers, Control Group - No Interventions
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 19 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Navigating Financial and Health-Related Social Needs in Adolescent and Young Adult Cancer Survivors (AYA-NAV)

NCT06950983
View directory record Official record
Conditions
Cancer in Adolescence
Interventions
AYA-NAV
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
15 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Patient-provider Decision Aid for HIV Post-exposure Prophylaxis Following Sexual Assault

NCT06139354
View directory record Official record
Conditions
Hiv
Interventions
decision aid
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit)

NCT02823028
View directory record Official record
Conditions
Smoking Cessation
Interventions
NRT, Web Guide, Tweet2Quit
Drug · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
21 Years to 59 Years
Enrollment
980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Irvine, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Improving Adherence in Renal Dialysis Patients Through Electronic Interventions

NCT02970201
View directory record Official record
Conditions
Endstage Renal Disease
Interventions
EpxDialysis
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality Distraction During Outpatient Pediatric Orthopedic Procedures

NCT05510232
View directory record Official record
Conditions
Fractures, Bone, Deformity; Bone
Interventions
A treatment group that will watch a non-VR video via an iPad, A treatment group that will have headset on and will watch a non-VR video, A treatment group that will be immersed in the VR game (Bear Blast) via the headset.
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
4 Years to 14 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Electronic Health Record Strategies to Promote Diverse Participation in Research AIM 2

NCT06467487
View directory record Official record
Conditions
Patient Participation
Interventions
Traditional Letter, Direct to Patient Message, Optimized Letter, Direct to Patient Message - Optimized
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
214,526 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Decision-Framing in Psoriasis

NCT04136314
View directory record Official record
Conditions
Psoriasis Vulgaris, Psoriatic Arthritis, Psoriasis
Interventions
Decision-Framed Survey
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Oct 22, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

NCT05056077
View directory record Official record
Conditions
Bladder Cancer, Breast Cancer, Colon Cancer, Endometrial Cancer, Ovarian Cancer, Rectal Cancer, Prostate Cancer, Renal Cell Carcinoma, Kidney Cancer
Interventions
Counseling, Educational Intervention, Health Education, Health Promotion and Education - Direct Text Messaging, Health Promotion and Education - Digital health tool kit, Questionnaires
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Explore Transplant at Home: Improving Low-Income ESRD Patients' Transplant Knowledge

NCT02268682
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
Patient-Guided, Educator-Guided
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 74 Years
Enrollment
558 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Educational Intervention to Minimize Disparities in Humanpapillomavirus Vaccination

NCT02145156
View directory record Official record
Conditions
HPV Vaccination Status
Interventions
Tailored educational materials, Untailored educational materials, Survey-only
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
1,294 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

Telemedicine Optimized Burn Intervention

NCT05019144
View directory record Official record
Conditions
Burns, Pediatric ALL
Interventions
Face-to-face burn care, Telemedicine enhanced burn care
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
0 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

CommunityRx-Cardiovascular Disease

NCT06264726
View directory record Official record
Conditions
Cardiovascular Diseases, Self Efficacy
Interventions
HealtheRx
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
2 Years and older
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Rocky Mount, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

NCT05721326
View directory record Official record
Conditions
Genetic Predisposition to Disease, Breast Cancer Female, Ovarian Cancer, Hereditary Breast and Ovarian Cancer, Hereditary Cancer Syndrome, Hereditary Diseases, Gene Mutation-Related Cancer
Interventions
Sequential EHR Communications
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
25 Years to 100 Years · Female only
Enrollment
1,283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 22, 2026, 2:05 AM EDT