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Showing 1–24 of 182 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Distress Reduction Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Online Training Tools in Pediatric Resuscitation

NCT03640520
View directory record Official record
Conditions
Family-centered Care in Pediatric Resuscitation
Interventions
FACETS: Pediatric Resuscitation, Control
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
547 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
New Haven, Connecticut • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional Results available

Digital Behavioral Interventions in Inflammatory Bowel Disease

NCT04861597
View directory record Official record
Conditions
Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases, Stress, Psychological, Depression, Anxiety
Interventions
Internet based cognitive behavioral therapy, Digital mood tracking
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive and Emotional Skills to Aid Smoking Prevention

NCT03058991
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
12 Years to 16 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 2, 2026, 4:37 PM EDT
Withdrawn Not applicable Interventional

Hypnotherapy in Major Surgical Procedures

NCT02376634
View directory record Official record
Conditions
Scoliosis, Pectus Excavatum
Interventions
Hypnosis
Behavioral
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Sep 2, 2026, 4:37 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection.

NCT04324021
View directory record Official record
Conditions
SARS-CoV-2
Interventions
Emapalumab, Anakinra
Biological
Lead sponsor
Swedish Orphan Biovitrum
Industry
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
5
States / cities
Saint Paul, Minnesota • Ridgewood, New Jersey • Flushing, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Sep 2, 2026, 4:37 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Multicomponent Physical Activity Intervention for the Reduction of Psychosocial Distress in Cancer Patients

NCT05056831
View directory record Official record
Conditions
Anxiety Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Behavioral Intervention, Best Practice, Informational Intervention, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional Results available

Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)

NCT05413239
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Psychoeducation to reduce diabetes distress and improve glycemic outcomes
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
14 Years to 25 Years
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

Distraction for Reduction of Pain Associated With Venipuncture in the Pediatric Post-Transplant Population

NCT03004456
View directory record Official record
Conditions
Pain, Procedural, Distress, Procedural, Venipuncture
Interventions
Distraction
Other
Lead sponsor
Columbia University
Other
Eligibility
4 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

Mindfulness-based Stress Reduction in Breast Cancer Recovery

NCT00584142
View directory record Official record
Conditions
Breast Cancer
Interventions
Mindfulness-Based Stress Reduction
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
21 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2012 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

Supporting Parents of Young Children With Type 1 Diabetes in Closed-Loop System

NCT03354286
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Developmental & Technological Demands, Distress Reduction, Nutrition, Set Point, & C:I Ratio, Hypoglycemia management, Minimal Intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 6 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

Virtual Reality for Youth Phobias

NCT05839431
View directory record Official record
Conditions
Specific Phobia, Social Anxiety Disorder, Autism Spectrum Disorder
Interventions
Virtual Reality for Youth Phobias
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
8 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

COMFORT Caregiver Intervention in Improving Communication and Reducing Distress in Caregivers of Patients With Lung Cancer

NCT02603367
View directory record Official record
Conditions
Caregiver
Interventions
Communication Intervention, Educational Intervention, Psychosocial Support for Caregiver, Questionnaire Administration
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2017 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Phase 1 Interventional Results available

Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS)

NCT04530604
View directory record Official record
Conditions
COVID, Sars-CoV2, COVID-19, Acute Respiratory Distress Syndrome
Interventions
Defibrotide
Drug
Lead sponsor
Gregory Yanik
Other
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL)

NCT04629599
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Interpersonal psychotherapy for major depression following perinatal loss, Coping with Depression
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 2, 2026, 4:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

NCT06732375
View directory record Official record
Conditions
Cancer, Youth Cancer, Young Adult Cancer, Distress, Psychological
Interventions
Mindset Moments
Behavioral
Lead sponsor
Duke University
Other
Eligibility
19 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Narrative Intervention to Decrease Abortion Stigma

NCT03865199
View directory record Official record
Conditions
Stigma, Social
Interventions
Narrative Intervention
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 19, 2020 · Synced Sep 2, 2026, 4:37 PM EDT
Terminated Not applicable Interventional

Coaching and Education for Diabetes Distress

NCT03617146
View directory record Official record
Conditions
Diabetes Distress
Interventions
Health coaching, Diabetes Distress-specific Education
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 2, 2026, 4:37 PM EDT
Terminated Not applicable Interventional Results available

Airway Pressure Release Ventilation in Acute Lung Injury

NCT00750204
View directory record Official record
Conditions
Acute Lung Injury, Acute Respiratory Distress Syndrome, Mechanical Ventilation
Interventions
APRV, Conventional MV
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 2, 2026, 4:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Early Adolescent Skills for Emotions

NCT06934954
View directory record Official record
Conditions
Community Mental Health Services
Interventions
EASE
Behavioral
Lead sponsor
The New School
Other
Eligibility
10 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 2, 2026, 4:37 PM EDT
Terminated Phase 2 Interventional Results available

Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department Care

NCT03756038
View directory record Official record
Conditions
Acute Pain
Interventions
Placebos, Lorazepam
Drug
Lead sponsor
Maria Pacella
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Phase 2Phase 3 Interventional

Effectiveness of Cognitive Behavioral Couples Therapy for Post-traumatic Stress Disorder

NCT00669981
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Cognitive behavioral couples therapy for post-traumatic stress disorder (CBCT for PTSD)
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

Reducing Emotional Distress, Enhancing Function and Improving Network Engagement in Adolescent and Young Adult Oncology

NCT02495376
View directory record Official record
Conditions
Cancer
Interventions
MBSR
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 39 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional

Healthcare Provider Behavior and Children's Perioperative Distress

NCT01878747
View directory record Official record
Conditions
Pain, Postoperative, Infant Behavior
Interventions
Provider Tailored Intervention for Perioperative Stress
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
2 Years to 14 Years
Enrollment
1,471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
5
States / cities
Los Angeles, California • Menlo Park, California • Orange, California + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 2, 2026, 4:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mindful Stress Reduction in Diabetes Self-management Education for Veterans

NCT02928952
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Mind-STRIDE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 2, 2026, 4:37 PM EDT