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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:00 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 183 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Distress Reduction Clear all
Recruiting Not applicable Interventional

Engage Psychosocial Intervention for Cancer Symptoms

NCT06555588
View directory record Official record
Conditions
Advanced Breast Cancer, Advanced Prostate Cancer, Advanced Lung Cancer, Advanced Colorectal Carcinoma, Advanced Colorectal Adenocarcinoma
Interventions
ENGAGE, Supportive Care
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional

Screening & TReatment fOr Perinatal WomeN With PTSD in Substance Use Care SettinGs in Arkansas (STRONG Moms)

NCT07759882
View directory record Official record
Conditions
Written Exposure Therapy
Interventions
Written Exposure Therapy (WET)
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional Results available

Decreasing Stress in Diabetes

NCT04016415
View directory record Official record
Conditions
Stress, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Interventions
Mindfulness Based Stress Reduction, Stress Management Education
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional

Mindfulness-Based Diabetes Education for Adults With Elevated Diabetes Distress

NCT05195138
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Mindfulness-Based Diabetes Education, Standard Diabetes Self-Management Education (DSME)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 70 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Reducing Immunization Distress (RID)

NCT01379885
View directory record Official record
Conditions
Pain
Interventions
Standard technique, Parent participation technique
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
4 Years to 6 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2013 · Synced Oct 20, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking

NCT06501677
View directory record Official record
Conditions
Alcohol; Use, Problem
Interventions
WBI
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Phase 2Phase 3 Interventional

Effectiveness of Cognitive Behavioral Couples Therapy for Post-traumatic Stress Disorder

NCT00669981
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Cognitive behavioral couples therapy for post-traumatic stress disorder (CBCT for PTSD)
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2013 · Synced Oct 20, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional

Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients

NCT06015932
View directory record Official record
Conditions
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Interventions
Cognitive Behavior Therapy, Questionnaire Administration
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Phase 1 Interventional Results available

Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS)

NCT04530604
View directory record Official record
Conditions
COVID, Sars-CoV2, COVID-19, Acute Respiratory Distress Syndrome
Interventions
Defibrotide
Drug
Lead sponsor
Gregory Yanik
Other
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Oct 20, 2026, 4:00 AM EDT
Terminated Not applicable Interventional

Meditation-Based Breathing Training in Improving Target Motion Management and Reducing Distress in Patients With Abdominal or Lung Cancer Undergoing Radiation Therapy

NCT01939210
View directory record Official record
Conditions
Anxiety, Depression, Digestive System Neoplasm, Lung Neoplasm, Pain, Post-Traumatic Stress Disorder, Psychological Impact of Cancer
Interventions
Educational Intervention, Meditation Therapy, Questionnaire Administration
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2018 · Synced Oct 20, 2026, 4:00 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility and Acceptability of Empowered Relief for American Indians With Pain During and After Cancer Treatment

NCT07742449
View directory record Official record
Conditions
Cancer, Pain, Pain Management, Chronic Pain, American Indian or Alaska Native
Interventions
Empowered Relief
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Phase 1Phase 2 Interventional

Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial

NCT01242462
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Conventional Pressure Controlled SIMV, Mid-frequency Ventilation
Procedure · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Hour to 7 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional

Collaborative Adolescent Research on Emotions and Suicide

NCT01528020
View directory record Official record
Conditions
Suicidal and Self-injurious Behaviour
Interventions
Dialectical Behavior Therapy, Individual and Group Supportive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 17 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Oct 20, 2026, 4:00 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

REducing pSychological diSTress To Optimize Recovery of Elderly ICU Survivors and Caregivers (RESTORE-ICU)

NCT06867367
View directory record Official record
Conditions
Relationship, Family, Well-Being, Psychological
Interventions
Isha Kriya and Naddi Shuddhi
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional

Reducing Distress And Improving Glycemic Control In Adults With Type 1 Diabetes

NCT02175732
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
'KnowIt', 'OnTrack'
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
19 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional

Reducing Emotional Distress, Enhancing Function and Improving Network Engagement in Adolescent and Young Adult Oncology

NCT02495376
View directory record Official record
Conditions
Cancer
Interventions
MBSR
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 39 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Online Training Tools in Pediatric Resuscitation

NCT03640520
View directory record Official record
Conditions
Family-centered Care in Pediatric Resuscitation
Interventions
FACETS: Pediatric Resuscitation, Control
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
547 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
New Haven, Connecticut • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 20, 2026, 4:00 AM EDT
Terminated Not applicable Interventional Results available

Bringing Exposure Therapy to Real-Life Context With Augmented Reality

NCT03649347
View directory record Official record
Conditions
Phobias Snakes, Phobias Spiders
Interventions
Augmented reality exposure therapy
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Oct 20, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional

SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Improve Stroke Outcomes

NCT06397937
View directory record Official record
Conditions
Stroke, Social Determinants of Health
Interventions
SHIFT team intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 75 Years
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 20, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Early Adolescent Skills for Emotions

NCT06934954
View directory record Official record
Conditions
Community Mental Health Services
Interventions
EASE
Behavioral
Lead sponsor
The New School
Other
Eligibility
10 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Phase 1 Interventional

Intervention for Anxiety After Falls

NCT01268657
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Specific Phobia, Anxiety
Interventions
Education, Relaxation Training, Cognitive Restructuring, Behavioral Activation, Exposure
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years to 105 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional

FRESH-TEEN: Families Responsibility Education Support Health for Teens

NCT03674944
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss (BWL) + Emotion Regulation (ER), Behavioral Weight Loss (BWL)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
13 Years to 16 Years
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
La Jolla, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Oct 20, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

NCT06001814
View directory record Official record
Conditions
Hiv, Cardiovascular Diseases
Interventions
One-Mind One-Heart, Education
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 20, 2026, 4:00 AM EDT
Completed Not applicable Interventional Results available

Acceptance-based Group Intervention for Binge Eating

NCT01757847
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2016 · Synced Oct 20, 2026, 4:00 AM EDT