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Showing 1–24 of 75 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Distress Tolerance Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive and Emotional Skills to Aid Smoking Prevention

NCT03058991
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
12 Years to 16 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 2, 2026, 4:15 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users

NCT06085222
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Emotional Engagement Distress Tolerance Intervention, Health Education Intervention
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Smoking Cessation Intervention for Diabetic Patients

NCT01501877
View directory record Official record
Conditions
Smoking, Type 2 Diabetes
Interventions
Acceptance and Commitment Therapy, Standard smoking cessation intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional

Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults

NCT06158581
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
The Emotion Awareness and Skills Enhancement Program, The Unified Protocol
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 30 Years
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Tuscaloosa, Alabama • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Treatment for Relationships and Safety Together

NCT04816149
View directory record Official record
Conditions
Suicide, Interpersonal Relations
Interventions
VA Standard Suicide Intervention, Treatment for Relationships and Safety Together (TR&ST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Active, not recruiting Not applicable Interventional

DBT Skills Groups for Veterans at High Risk for Suicide Attempt

NCT05000749
View directory record Official record
Conditions
Suicide, Attempted
Interventions
DBT-SG, VHA treatment as usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
San Diego, California • West Haven, Connecticut • Tampa, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Comparing Two Treatments That Both Target Smoking Cessation and Weight Loss at the Same Time.

NCT04130698
View directory record Official record
Conditions
Smoking Cessation, Weight Loss
Interventions
Distress Tolerance, transdermal nicotine patch, Active Health Control
Behavioral · Drug
Lead sponsor
Rhode Island College
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Unified Protocol for Adolescents (UP-A) Change Processes

NCT03102008
View directory record Official record
Conditions
Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem, Emotional Disorder
Interventions
Unified Protocol for Emotional Disorders in Adolescents (UP-A)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Results available

Horyzons: Implementation in Clinical Practice

NCT04673851
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders, Unspecified Schizophrenia Spectrum and Other Psychotic Disorder
Interventions
Horyzons USA
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 35 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional

A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial

NCT07119489
View directory record Official record
Conditions
Smoking Behavior
Interventions
Dialectical Behavior Therapy -Skill Training brief intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Not yet recruiting Not applicable Interventional

Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain

NCT07513662
View directory record Official record
Conditions
Migraine, Migraine in Adolescence
Interventions
BREATHE with Headache (BREATHE-HA), Enhanced Standard-of-Care: Headache Education
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Optimizing Suicide Prevention Strategies for Pediatric Primary Care

NCT06194331
View directory record Official record
Conditions
Suicidal Ideation, Suicidal and Self-injurious Behavior, Depression
Interventions
iCHART/cASAP, Treatment as usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Itasca, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Results available

Patient-caregiver Communication Intervention for Prognostic Understanding

NCT03833817
View directory record Official record
Conditions
Advanced Cancer
Interventions
Talking about Cancer (TAC)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digital Health Intervention to Support Opioid Use Disorder Treatment

NCT03842384
View directory record Official record
Conditions
Opioid Use Disorder, Treatment Adherence
Interventions
iENDURE
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional

Redefining BMI: The Body, Mind, and Inflammation Trial

NCT06532747
View directory record Official record
Conditions
Obesity, Adiposity
Interventions
Integrated Lifestyle Intervention (ILI), Monitoring with digital tools
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Dialectical Behavior Therapy for Pregnant Women

NCT03938350
View directory record Official record
Conditions
Perinatal Depression
Interventions
Dialectical Behavior Therapy (DBT) Skills Training
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2022 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

The Development and Evaluation of a Single Session Intervention for Parent Distress Tolerance

NCT05955898
View directory record Official record
Conditions
Parents, Mental Health Issue, Distress, Emotional
Interventions
Parents THRIVE, Sharing Feelings Project
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence

NCT04625465
View directory record Official record
Conditions
Alcohol Consumption, Violence, Domestic, Stress, Psychological, Aggression
Interventions
CBT Text Messaging, Attention Control Text Messaging
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
21 Years and older
Enrollment
474 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Modified Interactive Screening Program Plus MINDBODYSTRONG: A Mental Health Resiliency Intervention for Nurses

NCT05582343
View directory record Official record
Conditions
Suicide Threat, Burnout, Professional, Depression
Interventions
MINDBODYSTRONG™
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
849 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Not listed Not applicable Interventional

Emotion Regulation Interventions for Preventing Collegiate Escalations in Drinking

NCT04492982
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Yoga, Distress Tolerance
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
Not listed
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Women Engaging in Quitting Smoking Together (WE QUIT)

NCT02051803
View directory record Official record
Conditions
Smoking Cessation
Interventions
Distress Tolerance Treatment for Weight Concern (DT-W), Health Education (HE)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 30, 2015 · Synced Sep 2, 2026, 4:15 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Piloting a School-Based Distress Tolerance Skills Program for Adolescents

NCT06638853
View directory record Official record
Conditions
Distress, Emotional, Internalizing Mental Health Symptoms
Interventions
Distress Tolerance Skills Training
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
11 Years to 14 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Beaverton, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional

Interoceptive Exposure for Adolescents With Low Weight Eating Disorders

NCT05763849
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Interoceptive Exposure Treatment (IE), Family-Based Treatment (FBT)
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Collaborative Adolescent Research on Emotions and Suicide

NCT01528020
View directory record Official record
Conditions
Suicidal and Self-injurious Behaviour
Interventions
Dialectical Behavior Therapy, Individual and Group Supportive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 17 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Sep 2, 2026, 4:15 PM EDT