- Conditions
- Glaucoma, Open-Angle, Glaucoma; Drugs
- Interventions
- dorzolamide/timolol
- Drug
- Lead sponsor
- CT Glaucoma Associates
- Other
- Eligibility
- 25 Years to 90 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Norwalk, Connecticut
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 25
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension, Elevated Intraocular Pressure
- Interventions
- ALZ-1101, Latanoprost
- Drug
- Lead sponsor
- Alleanza Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Morrow, Georgia
- Conditions
- X-linked Retinoschisis, XLRS
- Interventions
- Dorzolamide 2% TID or brinzolamide 1% TID
- Drug
- Lead sponsor
- Beacon Therapeutics
- Industry
- Eligibility
- 7 Years and older · Male only
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 3
- States / cities
- Ann Arbor, Michigan • Portland, Oregon • Dallas, Texas
- Conditions
- Open-Angle Glaucoma
- Interventions
- bimatoprost 0.03%, dorzolamide 2%/timolol maleate 0.5% fixed combination, placebo
- Drug
- Lead sponsor
- Pharmaceutical Research Network
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 3
- States / cities
- Louisville, Kentucky • Mt. Pleasant, South Carolina • Houston, Texas
- Conditions
- Glaucoma
- Interventions
- glaucoma medications (Timolol, Brimonidine, Dorzolamide, Brinzolamide)
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Glaucoma
- Interventions
- fixed combination of brimonidine tartrate 0.2% timolol maleate 0.5% ophthalmic solution, fixed combination of dorzolamide hydrochloride timolol maleate ophthalmic solution
- Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 30 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Glaucoma
- Interventions
- Cosopt (combination eyedrop of dorzolamide and timolol)
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Glaucoma
- Interventions
- Brimonidine Purite 0.15%, Dorzolamide 2%, Latanoprost
- Drug
- Lead sponsor
- Innovative Medical
- Industry
- Eligibility
- 18 Years and older
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Neovascular Age-related Macular Degeneration, Wet Macular Degeneration
- Interventions
- Dorzolamide-timolol, Artificial tears
- Drug · Other
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 5
- States / cities
- Palo Alto, California • Boston, Massachusetts • Royal Oak, Michigan + 2 more
- Conditions
- Open-Angle Glaucoma, Ocular Hypertension
- Interventions
- timolol maleate 0.5%, dorzolamide/timolol maleate fixed combination, latanoprost 0.005%, placebo
- Drug
- Lead sponsor
- Pharmaceutical Research Network
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005
- U.S. locations
- 2
- States / cities
- Lakeland, Florida • Bourbonnais, Illinois
- Conditions
- Exfoliation Syndrome, Glaucoma, Ocular Hypertension
- Interventions
- Latanoprost with Pilocarpine vs Timolol or Cosopt
- Drug
- Lead sponsor
- The New York Eye & Ear Infirmary
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 277 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2000 – 2008
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Glaucoma
- Interventions
- timolol maleate and dorzolamide hydrochloride
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Scleral Buckling
- Interventions
- Timolol-dorzolamide (Glaucoma drops), standard post-operative topical drops
- Drug
- Lead sponsor
- Jason Hsu, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Ocular Hypertension, Open-Angle Glaucoma, Exfoliation Syndrome, Glaucoma, Pigmentary
- Interventions
- timolol maleate, dorzolamide/timolol maleate fixed combination
- Drug
- Lead sponsor
- Pharmaceutical Research Network
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 5
- States / cities
- Little Rock, Arkansas • Atlanta, Georgia • Bourbonnais, Illinois + 2 more
- Conditions
- Retinal Degenerations
- Interventions
- 2% dorzolamide
- Drug
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2017
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Glaucoma
- Interventions
- Latanoprost, Bimatoprost, Travoprost, Timolol, Dorzolamide, Brinzolamide, Acetazolamide, Methazolamide
- Drug
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2024
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
- Interventions
- Lumega-Z, Dorzolamide Hcl 2% Oph Soln, Placebo
- Dietary Supplement · Drug · Other
- Lead sponsor
- University of the Incarnate Word
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension
- Interventions
- Brimonidine purite 0.15%, Dorzolamide 2%, Brinzolamide 1%
- Drug
- Lead sponsor
- Northwestern Ophthalmic Institute S.C.
- Other
- Eligibility
- 41 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Glenview, Illinois
- Conditions
- Glaucoma
- Interventions
- (Cosopt®, prostaglandin)
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Glaucoma
- Interventions
- Latanoprost, Dorzolamide, Timolol
- Drug
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Open Angle Glaucoma
- Interventions
- Cosopt, Xalatan
- Drug
- Lead sponsor
- Advanced Glaucoma Specialists
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2006
- U.S. locations
- 1
- States / cities
- Reading, Massachusetts
- Conditions
- Macular Hole, Retinal Detachment
- Interventions
- Dorzolamide 2%-timolol 0.5% topical eyedrops
- Drug
- Lead sponsor
- Mid Atlantic Retina
- Other
- Eligibility
- Not listed
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Open Angle Glaucoma
- Interventions
- Simbrinza 0.2%-1% Ophthalmic Suspension, Rocklatan 0.02%-0.005% Ophthalmic Solution, Cosopt PF 2%-0.5% Ophthalmic Solution, Latanoprost 0.005% Ophthalmic Solution
- Drug
- Lead sponsor
- Prairie Eye Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Springfield, Illinois
- Conditions
- Wet Macular Degeneration, Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
- Interventions
- Dorzolamide-timolol
- Drug
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania