- Conditions
- Sepsis, Septic Shock
- Interventions
- drotrecogin alfa (activated)
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 2
- States / cities
- Camden, New Jersey • Akron, Ohio
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Showing 1–13
of 13
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Sepsis
- Interventions
- Drotrecogin alfa activated
- Drug
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- Not listed
- Enrollment
- 12,492 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Severe Sepsis
- Interventions
- Drotrecogin alfa (activated)
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 486 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 17
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Fresno, California + 14 more
- Conditions
- Sepsis
- Interventions
- Drotrecogin alfa (activated), Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,696 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 23
- States / cities
- Birmingham, Alabama • Loma Linda, California • Long Beach, California + 20 more
- Conditions
- Sepsis
- Interventions
- Drotrecogin alfa (activated)
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 152
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 149 more
- Conditions
- Severe Sepsis, Septic Shock
- Interventions
- Not listed
- Lead sponsor
- Sirius Genomics Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 3,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 4
- States / cities
- Atlanta, Georgia • Baltimore, Maryland • Boston, Massachusetts + 1 more
- Conditions
- Respiratory Distress Syndrome, Adult
- Interventions
- Xigris
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 9
- States / cities
- Fresno, California • Los Angeles, California • San Francisco, California + 5 more
- Conditions
- Sepsis, Hypotension
- Interventions
- Drotrecogin Alfa (Activated), placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- End Stage Renal Disease
- Interventions
- Drotrecogin alfa activated (Xigris)
- Drug
- Lead sponsor
- George Washington University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Sepsis, Hematologic Neoplasms, Hematopoietic Stem Cell Transplantation, Infection
- Interventions
- Drotrecogin Alfa (activated)
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003
- U.S. locations
- 5
- States / cities
- Denver, Colorado • Iowa City, Iowa • Manhassaet, New York + 2 more
- Conditions
- Lung Inflammation
- Interventions
- placebo pill and placebo IV, Lovastatin pill and placebo IV, placebo pill and recombinant human activated protein C IV, Endotoxin
- Drug · Biological
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 19 Years to 44 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Stroke
- Interventions
- Activated Protein C
- Drug
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 9
- States / cities
- Orange, California • Maywood, Illinois • St Louis, Missouri + 4 more
- Conditions
- Sepsis
- Interventions
- Drotrecogin alfa (activated), Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- Up to 17 Years
- Enrollment
- 474 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2005
- U.S. locations
- 23
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Tuscon, Arizona + 20 more