- Conditions
- Dry Eye Disease
- Interventions
- FID123300 ocular lubricant
- Other
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 188 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 9
- States / cities
- Maitland, Florida • Orlando, Florida • Franklin Park, Illinois + 6 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 497
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Dry Eye
- Interventions
- Artificial tears
- Drug
- Lead sponsor
- Thomas O Salmon, OD, PhD
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- Tahlequah, Oklahoma
- Conditions
- Dry Eye Disease
- Interventions
- INV-102, Vehicle
- Drug
- Lead sponsor
- Invirsa, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Rush, New York
- Conditions
- Ocular GVHD
- Interventions
- Tacrolimus, Methylprednisolone Sodium Succinate
- Drug
- Lead sponsor
- Massachusetts Eye and Ear Infirmary
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Dry Eye Syndrome
- Interventions
- RGN-259, Placebo
- Drug
- Lead sponsor
- ReGenTree, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 317 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Keratoconjunctivitis Sicca, Xeropthalmia
- Interventions
- Acupuncture, Sham acupuncture
- Procedure
- Lead sponsor
- Walter Reed Army Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Dry Eye Syndrome
- Interventions
- cis-UCA ophthalmic solution 1.0%, cis-UCA ophthalmic solution 2.5%, Placebo ophthalmic solution
- Drug
- Lead sponsor
- Herantis Pharma Plc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 161 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Dry Eye Disease
- Interventions
- Systane Ultra, Saline solution, Maxidex
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Dry Eye
- Interventions
- B & L Soothe Lubricant Eye Drops, Liposic EDO, OcuFresh Eye Wash
- Drug
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Evaporative Loss Dry Eye Disease
- Interventions
- Not listed
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Dry Eye Syndromes
- Interventions
- Euphrasia-based homeopathic therapy, Cyclosporin solution
- Drug
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Aqueous Deficient Dry Eye, Meibomium Gland Dysfunction
- Interventions
- Subjective Questionnaire, Measurement with wavefront sensor (right eye, then left eye), Instill Saline Drop
- Behavioral · Procedure · Drug
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 20 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Microbial Colonization, Eye Diseases, Ophthalmopathy
- Interventions
- Eye swab
- Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Dry Eye Disease (DED)
- Interventions
- SYSTANE® PRO, MIEBO™ (Perfluorohexyloctane, PFHO)
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 269 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 4
- States / cities
- Newport Beach, California • Bloomington, Indiana • Pittsburg, Kansas + 1 more
- Conditions
- Sjogren Syndrome With Keratoconjunctivitis
- Interventions
- TRYPTYR (Acoltremon ophthalmic solution 0.003%)
- Drug
- Lead sponsor
- Center For Sight
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Venice, Florida
- Conditions
- Meibomian Gland Dysfunction, Dry Eye
- Interventions
- LipiFlow System, Warm Compress Therapy + Lid Scrub
- Device
- Lead sponsor
- TearScience, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 9
- States / cities
- Fayetteville, Arkansas • Laguna Hills, California • Miami, Florida + 6 more
- Conditions
- Dry Eye Syndromes, Keratoconjunctivitis Sicca
- Interventions
- KPI-121 0.25% Ophthalmic Suspension, Vehicle of KPI-121 0.25% Ophthalmic Suspension
- Drug
- Lead sponsor
- Kala Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 918 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 60
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Little Rock, Arkansas + 53 more
- Conditions
- Dry Eye, Sjogren's Syndrome, Graft vs. Host Disease
- Interventions
- Thymosin Beta 4 eye drops, Vehicle Control
- Drug
- Lead sponsor
- Michigan Cornea Consultants, PC
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Southfield, Michigan
- Conditions
- Dry Eye Disease
- Interventions
- Reproxalap Ophthalmic Solution (0.25%), Placebo Comparator
- Drug
- Lead sponsor
- Aldeyra Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 757 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Meibomian Gland Dysfunction, Evaporative Dry Eye
- Interventions
- Dexamethasone, 0.4mg, Prednisone acetate, Control
- Drug · Other
- Lead sponsor
- Warrenville Eyecare
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Warrenville, Illinois
- Conditions
- Dry Eye
- Interventions
- Miebo
- Drug
- Lead sponsor
- Bausch & Lomb Incorporated
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Petaluma, California • Pittsburg, Kansas + 4 more
- Conditions
- Dry Eye Syndrome
- Interventions
- PG101
- Drug
- Lead sponsor
- Rhodes Pharmaceuticals, L.P.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Dry Eye Syndrome
- Interventions
- TOP1630 Ophthalmic Solution, Placebo to TOP1630 Ophthalmic Solution
- Drug
- Lead sponsor
- ORA, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Dry Eye, Dry Eye Syndromes
- Interventions
- Vehicle Ophthalmic Solution, PL9643 Ophthalmic Solution
- Drug
- Lead sponsor
- Palatin Technologies, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 575 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 18
- States / cities
- Glendale, California • Newport Beach, California • Torrance, California + 15 more