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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:34 AM EDT

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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Dry Needling Clear all
Completed Not applicable Interventional

A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population

NCT06940492
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Dry needling
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional

Dry Needling for Sub Acromial Pain Syndrome

NCT03442894
View directory record Official record
Conditions
Subacromial Impingement Syndrome
Interventions
Standard Physical Therapy Treatment, Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling in Subjects With Delayed Onset Muscle Soreness

NCT03876080
View directory record Official record
Conditions
Delayed Onset Muscle Soreness
Interventions
Dry needling, Sham needling
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 17, 2026, 9:34 AM EDT
Not listed Not applicable Interventional

Effectiveness of Dry Needling in Linear Scar Tissue

NCT06033430
View directory record Official record
Conditions
Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar, Dry Needling
Interventions
True dry needling, Sham dry needling
Other
Lead sponsor
Iran University of Medical Sciences
Other
Eligibility
20 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Dry Needling on Muscle Stiffness, Gait, Motion, and Strength in Healthy Individuals With Trigger Points

NCT03689283
View directory record Official record
Conditions
Trigger Point Pain, Myofascial
Interventions
Dry Needling, Sham Dry Needlling
Other
Lead sponsor
Regis University
Other
Eligibility
18 Years to 50 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature

NCT03580200
View directory record Official record
Conditions
Trigger Point, Muscle Weakness
Interventions
Trigger Point Dry Needling
Other
Lead sponsor
Emily Slaven, PT, PhD
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 17, 2026, 9:34 AM EDT
Withdrawn Not applicable Interventional

Dry Needling and Exercise Versus Traditional Physical Therapy for Biceps Tendinitis

NCT04073212
View directory record Official record
Conditions
Bicep Tendinitis, Biceps; Tenosynovitis, Bicipital Tendinitis, Left Shoulder, Bicipital Tendinitis, Right Shoulder, Bicipital Tendinitis, Unspecified Shoulder, Biceps Tendon Disorder
Interventions
Dry Needling, Heavy Slow Load Exercise, Rotator cuff and scapular stabilization exercise program, Soft tissue mobilization
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 17, 2026, 9:34 AM EDT
Recruiting Not applicable Interventional

The Effects of Dry Needling on Patients With Knee Pain

NCT02890485
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Dry Needling, Sham Dry Needling, Physical Therapy
Device · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 17, 2026, 9:34 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Dry Needling for Spasticity in Stroke

NCT04535479
View directory record Official record
Conditions
Stroke, Muscle Spasticity
Interventions
Dry Needling
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Triceps Surae Trigger Point Size and Muscle Extensibility

NCT02087969
View directory record Official record
Conditions
Limited Dorsiflexion, Limited Ankle Range of Motion
Interventions
Dry Needling, Stretching
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 15, 2017 · Synced Oct 17, 2026, 9:34 AM EDT
Active, not recruiting Not applicable Interventional

How Dry Needling at the Neck Affects Shoulder Movement, Strength, Pain, and Shoulder Circulation

NCT06705634
View directory record Official record
Conditions
Dry Needling Technique, Neck Pain Musculoskeletal, Shoulder Pain, Neck Pain, Dry Needling
Interventions
Dry Needling
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Effect of Dry Needling of the Lumbar Multifidus on Pain Sensitivity In A Healthy Population

NCT05845697
View directory record Official record
Conditions
Low Back Pain
Interventions
Trigger point dry needling, Sham dry needling
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 17, 2026, 9:34 AM EDT
Recruiting Not applicable Interventional

Treatment Validation for Myofascial Pain

NCT07133139
View directory record Official record
Conditions
Chronic Low-back Pain (cLBP), Myofacial Pain
Interventions
Dry Needling, Sham Dry Needling, NUN Biomarker
Device · Other
Lead sponsor
Ajay Wasan, MD, Msc
Other
Eligibility
20 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional

Periosteal Electrical Dry Needling for Knee Osteoarthritis

NCT05365061
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
periosteal electrical dry needling with no maintenance treatments, periosteal electrical dry needling with maintenance treatments every other month, periosteal electrical dry needling with monthly maintenance treatments
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years and older
Enrollment
586 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chamblee, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional

Dry Needling and Spinal Manipulation vs. Conventional PT for Lumbar Spinal Stenosis

NCT03167736
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
electric dry needling, manipulation, conventional physical therapy
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
50 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Canton, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 17, 2026, 9:34 AM EDT
Not yet recruiting Not applicable Interventional

Conservative Care for Pelvic Pain (C2P2) in Women Service Members

NCT06697548
View directory record Official record
Conditions
Chronic Pelvic Pain
Interventions
Pain Neuroscience Education, Lumbopelvic and Hip Therapeutic Exercise, Extrapelvic Manual Therapy, Extrapelvic Dry Needling, Deep Paced Diaphragmatic Breathing Training, Chronic Pelvic Pain Education, Intravaginal and intrarectal pelvic floor physical therapy
Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
San Antonio, Texas • Waco, Texas
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 17, 2026, 9:34 AM EDT
Recruiting Not applicable Interventional

Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II

NCT06502951
View directory record Official record
Conditions
Cervicogenic Headache, Whiplash Injuries
Interventions
Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated May 11, 2025 · Synced Oct 17, 2026, 9:34 AM EDT
Not listed Not applicable Interventional

Superficial Dry Needling for Cervicogenic Headache

NCT05444296
View directory record Official record
Conditions
Headache
Interventions
Superficial Dry Needling, Non-thrust Mobilizations only
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Early Phase 1 Interventional

Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling

NCT04170803
View directory record Official record
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Activity and Kinematic Changes With Dry Needling

NCT04295200
View directory record Official record
Conditions
Healthy
Interventions
Dry needling with electrical stimulation
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Phase 2 Interventional Results available

Platelet-Rich Plasma Therapy for Patellar Tendinopathy

NCT03136965
View directory record Official record
Conditions
Patellar Tendinitis
Interventions
PRP, Dry Needling, Dry Needling - Sham
Biological · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 39 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 17, 2026, 9:34 AM EDT
Terminated Not applicable Interventional

Manual Therapy to Treat Gluteus Medius Trigger Points

NCT02333617
View directory record Official record
Conditions
Anterior Knee Pain Syndrome, Patellofemoral Pain Syndrome
Interventions
Dry Needling, Soft Tissue Mobilization, Placebo Control, Hip and core strengthening exercises
Other
Lead sponsor
Mitchell Selhorst
Other
Eligibility
13 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Oct 17, 2026, 9:34 AM EDT
Completed Not applicable Interventional

Trigger Point Dry Needling vs Trigger Point Dry Needling With Intramuscular Electrical Stimulation

NCT03539588
View directory record Official record
Conditions
Sub-acute and Chronic Low Back Pain
Interventions
trigger point dry needling, Electrical Stimulation
Device
Lead sponsor
William Beaumont Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Oct 17, 2026, 9:34 AM EDT