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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Dry Needling - Sham Clear all
Completed Phase 2 Interventional Results available

Platelet-Rich Plasma Therapy for Patellar Tendinopathy

NCT03136965
View directory record Official record
Conditions
Patellar Tendinitis
Interventions
PRP, Dry Needling, Dry Needling - Sham
Biological · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 39 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Sep 6, 2026, 3:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Derivation of a Clinical Prediction Rule to Identify Those With Low Back Pain Who Will Respond Favorably to Intramuscular Dry-needling

NCT06204055
View directory record Official record
Conditions
Low Back Pain
Interventions
Intramuscular Dry-Needling
Other
Lead sponsor
Whitworth University
Other
Eligibility
18 Years to 60 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Sep 6, 2026, 3:15 AM EDT
Active, not recruiting Not applicable Interventional

Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity in Individuals with Shoulder Pain

NCT05596240
View directory record Official record
Conditions
Dry Needling, Shoulder Pain
Interventions
Dry Needling, Sham Dry Needling
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 6, 2026, 3:15 AM EDT
Terminated Not applicable Interventional

Dry Needling for Shoulder Adhesive Capsulitis

NCT03861923
View directory record Official record
Conditions
Shoulder Adhesive Capsulitis, Shoulder Pain, Frozen Shoulder
Interventions
Dry needling, Sham Dry Needling, Therapeutic Exercise
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 6, 2026, 3:15 AM EDT
Terminated Not applicable Interventional

Comparison of Platelet Rich Plasma and Alternative Therapies for the Treatment of Tennis Elbow (Lateral Epicondylitis)

NCT01668953
View directory record Official record
Conditions
Lateral Epicondylitis (Tennis Elbow)
Interventions
Platelet Rich Plasma (PRP) Injection, Whole Blood Injection, Dry Needle Fenestration, Sham Injection
Other
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 9, 2023 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Early Phase 1 Interventional

Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling

NCT04170803
View directory record Official record
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Sep 6, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

The Impact of Dry Needling on Electrophysiological and Ultrasound-based Biomarkers for Myofascial Pain

NCT07270276
View directory record Official record
Conditions
Trigger Point in Trapezius Muscle
Interventions
Dry Needling, Sham Treatment
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 6, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

Dry Needling in Multiple Sclerosis

NCT07615725
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 6, 2026, 3:15 AM EDT
Terminated Not applicable Interventional

Dry Needling and Functional Improvement

NCT02838394
View directory record Official record
Conditions
Myofascial Trigger Point Pain, Myofascial Pain Syndrome
Interventions
Dry needling, Sham dry needling
Procedure · Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling to the Multifidus Muscle in Subjects With Low Back Pain

NCT02284724
View directory record Official record
Conditions
Low Back Pain, Mechanical
Interventions
Dry Needling, Sham Needling
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Dry Needling for Patients With Neck Pain

NCT02731014
View directory record Official record
Conditions
Neck Pain
Interventions
Dry Needling, Sham Dry Needling, Manual Therapy, Exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Indianapolis, Indiana • Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 6, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

Dry Needling in Multiple Sclerosis

NCT06394310
View directory record Official record
Conditions
Multiple Sclerosis, Spasticity
Interventions
Dry needling, Sham dry needling
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Dry Needling for Sub Acromial Pain Syndrome

NCT03442894
View directory record Official record
Conditions
Subacromial Impingement Syndrome
Interventions
Standard Physical Therapy Treatment, Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Sep 6, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

The Effects of Dry Needling on Patients With Knee Pain

NCT02890485
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Dry Needling, Sham Dry Needling, Physical Therapy
Device · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Hamstring Tightness

NCT02516137
View directory record Official record
Conditions
Hamstring Tightness
Interventions
Dry needling, Sham needling, Blunt needle placement, Standard hamstring stretching exercise
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Short-Term Response of Thoracic Spine Manipulation With or Without Trigger Point Dry Needling for Mechanical Neck Pain

NCT02415660
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic spinal manipulation, Trigger point dry needling, Cervical range of motion exercises, Posterior neck muscle activation exercise, Trigger point dry needling sham, Seirin J-type stainless steel needles, 0-2-0.3 x 40-50 mm
Procedure · Behavioral · Device
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling in Subjects With Delayed Onset Muscle Soreness

NCT03876080
View directory record Official record
Conditions
Delayed Onset Muscle Soreness
Interventions
Dry needling, Sham needling
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility

NCT03630172
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kensington, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 6, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dry Needling Multifidus on Thickness of Transversus Abdominis in Healthy Individuals

NCT01734577
View directory record Official record
Conditions
Back Pain
Interventions
Dry needling, Sham needling
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 6, 2026, 3:15 AM EDT
Not listed Not applicable Interventional

Effectiveness of Dry Needling in Linear Scar Tissue

NCT06033430
View directory record Official record
Conditions
Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar, Dry Needling
Interventions
True dry needling, Sham dry needling
Other
Lead sponsor
Iran University of Medical Sciences
Other
Eligibility
20 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 6, 2026, 3:15 AM EDT
Enrolling by invitation Not applicable Interventional

Dry Needling and Exercise for Mid-portion Achilles Tendinopathy

NCT07642583
View directory record Official record
Conditions
Non-Insertional Achilles Tendinopathy
Interventions
Dry needling, Sham dry needling
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 6, 2026, 3:15 AM EDT
Not listed Not applicable Interventional

Dry Needling for Cervicogenic Headache

NCT05140291
View directory record Official record
Conditions
Headache
Interventions
Dry Needling, Sham Dry Needling
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 6, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

Treatment Validation for Myofascial Pain

NCT07133139
View directory record Official record
Conditions
Chronic Low-back Pain (cLBP), Myofacial Pain
Interventions
Dry Needling, Sham Dry Needling, NUN Biomarker
Device · Other
Lead sponsor
Ajay Wasan, MD, Msc
Other
Eligibility
20 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 6, 2026, 3:15 AM EDT