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Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Dual chamber pacemaker Clear all
Recruiting No phase listed Observational

AVEIR DR Coverage With Evidence Development (CED) Study

NCT05932602
View directory record Official record
Conditions
Cardiac Pacemaker, Arrythmia, Bradycardia
Interventions
Aveir DR Leadless Pacemaker System, Dual Chamber Transvenous Pacemaker
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,812 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

ENABLE MRI (Magnetic Resonance Imaging)

NCT02652481
View directory record Official record
Conditions
Magnetic Resonance Imaging
Interventions
ImageReady MR Conditional Defibrillation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
34
States / cities
Huntsville, Alabama • Jonesboro, Arkansas • Pasadena, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 1, 2026, 7:52 PM EDT
Completed No phase listed Observational

EMERALD - AssEssment of CoMorbidities & Atrial ArRhythmiA Burden in DuaL-Chamber PaceD Patients

NCT01188356
View directory record Official record
Conditions
Atrial Arrhythmia
Interventions
Not listed
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
4,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
32
States / cities
Mesa, Arizona • Peoria, Arizona • Phoenix, Arizona + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Sep 1, 2026, 7:52 PM EDT
Completed No phase listed Observational

Effects Rapid Atrial Pacing Has on the Electrocardiogram (ECG) in Patients With Dual Chamber Pacemakers

NCT00883610
View directory record Official record
Conditions
Prolonged QT Interval
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional

The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy

NCT03549468
View directory record Official record
Conditions
Ischemic Cardiomyopathy
Interventions
Low level tragus stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Effect of Ranolazine and Dronedarone When Given Alone and in Combination in Patients With Paroxysmal Atrial Fibrillation

NCT01522651
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Ranolazine, Dronedarone, Ranolazine placebo, Dronedarone placebo
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
15
States / cities
Beverly Hills, California • Newport Beach, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Phase 4 Interventional

Reduce Ventricular Pacing in Dual Chamber Implantable Cardioverter Defibrillators Using AutoIntrinsic Conduction Search Study

NCT00187239
View directory record Official record
Conditions
Arrhythmia
Interventions
Autointrinsic Conduction Search Algorithm
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

Advisa MRI Clinical Study

NCT01110915
View directory record Official record
Conditions
Magnetic Resonance Imaging, Cardiac Pacemaker, Artificial
Interventions
Medtronic Advisa MRI Implantable Pulse Generator (IPG), Medtronic CapSureFix MRI™ active fixation MRI lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Salinas, California • Orlando, Florida • West Des Moines, Iowa + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Sep 1, 2026, 7:52 PM EDT
Terminated Not applicable Interventional Results available

Optimize RV Selective Site Pacing Clinical Trial

NCT00422669
View directory record Official record
Conditions
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Interventions
Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
16
States / cities
Bridgeport, Connecticut • Clearwater, Florida • Hudson, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

ImageReady(TM) MR Conditional Pacing System Clinical Study

NCT01781078
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction
Interventions
MRI, ImageReady System implant
Radiation · Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
363 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
29
States / cities
Mesa, Arizona • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional

SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction

NCT00284830
View directory record Official record
Conditions
Sick Sinus Syndrome, Heart Failure, Congestive, Atrial Fibrillation, Bradycardia, Ventricular Dysfunction
Interventions
Implantable Pulse Generators
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,070 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
63
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Conway, Arkansas + 60 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2008 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Exenatide for Smoking Cessation and Prevention of Weight Gain

NCT05610800
View directory record Official record
Conditions
Smoking Cessation, Weight Gain
Interventions
Exenatide 2 milligram (mg) Injection, Placebo, Nicotine patch, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Phase 4 Interventional Results available

The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock

NCT00787800
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation, Supraventricular Tachycardia
Interventions
Dual Chamber ICD, Single Chamber ICD
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Sep 1, 2026, 7:52 PM EDT
Terminated Not applicable Interventional Results available

Investigational Device Exemption (IDE) Study for the Approval of Closed Loop Stimulation (CLS) and Cardiac Resyncronization Pacing Therapies (CRT) for the Treatment of Atrial Fibrillation (AF) With Ablate and Pace

NCT00356057
View directory record Official record
Conditions
Atrial Fibrillation, Congestive Heart Failure
Interventions
Protos DR/CLS and Stratos LV CRT pacemakers
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
10
States / cities
Birmingham, Alabama • Lake Charles, Louisiana • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2018 · Synced Sep 1, 2026, 7:52 PM EDT
Completed No phase listed Observational Results available

Imaging Study of Lead Implant for His Bundle Pacing

NCT03294317
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial
Interventions
His bundle pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Indianapolis, Indiana • Wilkes-Barre, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Users Study Of The Caverject Delivery System

NCT01747928
View directory record Official record
Conditions
Healthy
Interventions
dual-chamber syringe
Other
Lead sponsor
Pfizer
Industry
Eligibility
40 Years to 70 Years · Male only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated May 1, 2014 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure

NCT02145351
View directory record Official record
Conditions
Heart Failure With a Preserved Ejection Fraction, Heart Failure, Diastolic, Chronotropic Incompetence
Interventions
Rate adaptive atrial pacing using a dual-chamber pacemaker, Pacemaker system will be implanted but set to Pacing Off.
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Sep 1, 2026, 7:52 PM EDT
Completed No phase listed Observational

iBeat Wristwatch Validation Study

NCT03711695
View directory record Official record
Conditions
Arrythmia, Cardiac
Interventions
iBeat wristwatch device
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 85 Years
Enrollment
55 participants
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 1, 2026, 7:52 PM EDT
Not yet recruiting Not applicable Interventional

Cardiac Anodal Biphasic Pacing

NCT07173777
View directory record Official record
Conditions
Cardiac Pacing
Interventions
Cardiac Waveform Generator
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Phase 1 Interventional

A Phase I Study to Assess the Electrophysiologic Effects of BMS-394136 on the Atrium and Ventricle in Patients With Dual-Chamber Pacemakers or Defibrillators

NCT00162448
View directory record Official record
Conditions
Heart Diseases
Interventions
BMS-394136, Placebo
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
3
States / cities
Salisbury, Maryland • Ann Arbor, Michigan • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2008 · Synced Sep 1, 2026, 7:52 PM EDT
Not listed Not applicable Interventional

Physiologic Pacing for Symptomatic First-Degree Heart Block

NCT06245304
View directory record Official record
Conditions
Symptomatic First-degree Heart Block
Interventions
Dual chamber Medtronic pacemaker implantation., DDD-50 pacing program, AAI-DDD 50 pacing program
Device · Other
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 1, 2026, 7:52 PM EDT
Recruiting No phase listed Observational

His Bundle Pacing in Bradycardia and Heart Failure

NCT03008291
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation
Procedure
Lead sponsor
Yong-Mei Cha
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 1, 2026, 7:52 PM EDT
Terminated Phase 1 Interventional

Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers

NCT02153437
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
BMS-919373, Sotalol, Placebo for BMS-919373
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 1, 2026, 7:52 PM EDT
Completed Not applicable Interventional

Pacing in First-degree AV-block

NCT01985802
View directory record Official record
Conditions
First-degree AV-block, Pacing
Interventions
Pacing
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Sep 1, 2026, 7:52 PM EDT