- Conditions
- Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders
- Interventions
- Placebo, Lemborexant 10 mg
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 45 Years to 90 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 11
- States / cities
- Glendale, Arizona • San Diego, California • Brandon, Florida + 7 more
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- Conditions
- CNS
- Interventions
- E2006, Placebo comparator
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 2
- States / cities
- Culver City, California • Glendale, California
- Conditions
- Insomnia
- Interventions
- Lemborexant, Lemborexant-matched placebo, Zolpidem tartrate, Zolpidem-matched placebo
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 1,006 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 60
- States / cities
- Jasper, Alabama • Glendale, Arizona • Little Rock, Arkansas + 49 more
- Conditions
- Chronic Insomnia, Adults, Elderly
- Interventions
- E2006, Placebo
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 291 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 29
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Fountain Valley, California + 21 more
- Conditions
- Insomnia Disorder
- Interventions
- Lemborexant 5 mg, Lemborexant 10 mg, Lemborexant-matched placebo., Flurazepam 30 mg
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • Crestview Hills, Kentucky
- Conditions
- Insomnia
- Interventions
- E2006 1.0 mg, E2006 2.5 mg, E2006 5.0 mg, E2006 10.0 mg, E2006 25.0 mg, E2006 50.0 mg, E2006 100 mg, E2006 200 mg, Zolpidem 10 mg, E2006 Matched Placebo or Zolpidem Matched Placebo, E2006 Matched Placebo
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 122 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 2
- States / cities
- New York, New York • Cincinnati, Ohio
- Conditions
- Healthy Subjects
- Interventions
- LEM5, LEM10, ZOL, PBO
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 4
- States / cities
- Atlanta, Georgia • New York, New York • Raleigh, North Carolina + 1 more
- Conditions
- Healthy Volunteers
- Interventions
- E2006 2.5 mg, E2006 10 mg, E2006 25 mg, Placebo
- Drug
- Lead sponsor
- Eisai Inc.
- Industry
- Eligibility
- 20 Years to 55 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Glendale, California