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ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:43 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: ECOG Clear all
Recruiting No phase listed Observational

Cortical Spreading Depolarization After Severe Traumatic Brain Injury

NCT03321370
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Continuous electrocorticography post severe traumatic brain injury requiring neurosurgical intervention
Diagnostic Test
Lead sponsor
Hennepin County Medical Center, Minneapolis
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Phase 2 Interventional

Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC)

NCT01915602
View directory record Official record
Conditions
Carcinoma, Hepatocellular
Interventions
Refametinib (BAY86-9766), Sorafenib (BAY43-9006)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Phase 2 Interventional Results available

Erlotinib vs. Standard Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) and Eastern Cooperative Oncology Group (ECOG)Performance Status (PS) 2

NCT00085839
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
Tarceva (Trademark) (erlotinib HCl, OSI-774), Combination carboplatin and paclitaxel
Drug
Lead sponsor
OSI Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
19
States / cities
Greenbrae, California • San Diego, California • Fort Lauderdale, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Phase 2 Interventional Results available

A Study to Determine Safety of Durvalumab After Sequential Chemo Radiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

NCT03693300
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
Durvalumab
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Gainesville, Georgia • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Phase 1 Interventional

A Study of Intratumoral Injection of Interleukin-2 and Ipilimumab in Patients With Unresectable Stages III-IV Melanoma

NCT01672450
View directory record Official record
Conditions
Melanoma
Interventions
Intratumoral Ipilimumab and Interleukin-2
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 7, 2015 · Synced Sep 3, 2026, 5:43 AM EDT
Withdrawn Not applicable Interventional

Neurocognitive Basis of Attention and Eye Movement Guidance in the Real World Scenes

NCT04652856
View directory record Official record
Conditions
Cognition, Attention, Eye Movements
Interventions
Electrical Brain Stimulation, Sham Electrical Brain Stimulation
Device
Lead sponsor
Avniel Ghuman
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 12, 2022 · Synced Sep 3, 2026, 5:43 AM EDT
Enrolling by invitation Not applicable Interventional

The Neural Coding of Speech Across Human Languages

NCT05014841
View directory record Official record
Conditions
Epilepsy, Brain Tumor, Speech, Bilingualism
Interventions
Speech Tasks
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 3, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional

Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor

NCT05150093
View directory record Official record
Conditions
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor, Dystonia
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 3, 2026, 5:43 AM EDT
Completed No phase listed Observational

Characterization of Circulating Tumor Cells (CTC) From Patients With Metastatic Breast Cancer Using the CTC-Endocrine Therapy Index

NCT01701050
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Blood collection
Other
Lead sponsor
Janssen Diagnostics, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
18
States / cities
Phoenix, Arizona • Fort Myers, Florida • St. Petersburg, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Sep 3, 2026, 5:43 AM EDT
Recruiting Phase 2 Interventional

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

NCT05337618
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Full-band Electrocorticography, Treatment Algorithm
Diagnostic Test · Combination Product
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Not applicable Interventional Results available

ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis

NCT01393444
View directory record Official record
Conditions
Tetraplegia, Spinal Cord Injury, Brachial Plexus Injury, Muscular Dystrophy, ALS, Brainstem Stroke
Interventions
Implantation of ECoG sensors on the brain surface
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 11, 2016 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Phase 2 Interventional Results available

Bendamustine + Rituximab in Older Patients With Previously Untreated Diffuse Large B-cell Lymphoma

NCT01234467
View directory record Official record
Conditions
Diffuse Large B-Cell Lymphoma, Lymphoma, Diffuse Large-Cell, Diffuse Large-Cell Lymphoma, Lymphoma
Interventions
Bendamustine, Rituximab
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
7
States / cities
Boone, North Carolina • Chapel Hill, North Carolina • Concord, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Sep 3, 2026, 5:43 AM EDT
Completed No phase listed Observational Results available

Direct Measurement of Motor Cortical Responses to tDCS

NCT04759898
View directory record Official record
Conditions
Parkinson Disease
Interventions
transcranial direct current stimulation (invasive recording)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 3, 2026, 5:43 AM EDT
Completed No phase listed Observational

Correlate of Surface Electroencephalogram (EEG) With Implanted EEG Recordings (ECOG)

NCT03629743
View directory record Official record
Conditions
Anesthesia
Interventions
EEG, ECOG
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 3, 2026, 5:43 AM EDT
Enrolling by invitation Not applicable Interventional

TMS - Intracranial Electrodes

NCT03702127
View directory record Official record
Conditions
Epilepsy Intractable
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Aaron Boes
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 3, 2026, 5:43 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Assessment of Effect of Vagal Nerve Stimulator (VNS) on Electrocorticograms Recorded by Responsive Neurostimulator (RNS) in Patients With Drug Resistant Epilepsy

NCT03595072
View directory record Official record
Conditions
Epilepsy
Interventions
observation of VNS stimulation effects
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Sep 3, 2026, 5:43 AM EDT
Completed No phase listed Observational

Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Non-Metastatic, Post Menopausal Breast Cancer Patients

NCT01051609
View directory record Official record
Conditions
Breast Cancer
Interventions
History and Physical Exam, Grip Strength Measurement, Surveys, Blood Collection, Ultrasound of Hand/Wrist
Other · Behavioral · Procedure
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Sep 3, 2026, 5:43 AM EDT
Terminated No phase listed Observational Results available

Brain Networks and Consciousness

NCT04502550
View directory record Official record
Conditions
Loss of Consciousness, Parkinson Disease, Essential Tremor, Anesthesia
Interventions
Propofol
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 3, 2026, 5:43 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Effects of Infrasound Exposure on Measures of Endolymphatic Hydrops

NCT03132961
View directory record Official record
Conditions
Vestibular Abnormality, Endolymphatic Hydrops
Interventions
Infrasound exposure
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Sep 3, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Brain Excitability in Depression

NCT07242105
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Active Single-Pulse TMS, Sham Single-Pulse TMS, TARGET-optimized TMS, Non-optimized (Open-Loop) TMS, EEG Recording, Intracranial EEG (iEEG) Recording
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Iowa City, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 3, 2026, 5:43 AM EDT
Completed No phase listed Observational

Identification of Genes Associated With Cancer in Patients and Siblings Who Have Cancer

NCT00003329
View directory record Official record
Conditions
Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
Interventions
gene mapping
Genetic
Lead sponsor
Eastern Cooperative Oncology Group
Network
Eligibility
0 Years to 120 Years
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
32
States / cities
Rancho Mirage, California • Fort Collins, Colorado • Boca Raton, Florida + 22 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Sep 3, 2026, 5:43 AM EDT
Completed No phase listed Observational

Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial

NCT00897767
View directory record Official record
Conditions
Leukemia, Lymphoma
Interventions
biologic sample preservation procedure
Other
Lead sponsor
Eastern Cooperative Oncology Group
Network
Eligibility
0 Years to 120 Years
Enrollment
1,873 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
214
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Aurora, Colorado + 156 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 3, 2026, 5:43 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Sirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer

NCT00311623
View directory record Official record
Conditions
Prostate Cancer
Interventions
Rapamycin 3mg, Rapamycin 6mg, Radical prostatectomy
Drug · Procedure
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Baltimore, Maryland • Ann Arbor, Michigan • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Sep 3, 2026, 5:43 AM EDT
Enrolling by invitation Not applicable Interventional

The Effect of Thalamic Stimulation on Sleep Oscillations

NCT07217080
View directory record Official record
Conditions
Sleep, Neuromodulation
Interventions
Effect of Electrical Stimulation on Sleep
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
5 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 3, 2026, 5:43 AM EDT