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Showing 1–24 of 163 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: EEG biofeedback Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

NCT02766374
View directory record Official record
Conditions
Asthma
Interventions
Heart rate variability biofeedback, Placebo
Behavioral
Lead sponsor
Fred Wamboldt, MD
Other
Eligibility
18 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
2
States / cities
Denver, Colorado • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 2, 2026, 6:33 AM EDT
Recruiting Not applicable Interventional

Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery

NCT04912531
View directory record Official record
Conditions
Postoperative Pain, Anxiety Postoperative, Opioid Use
Interventions
Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG, Essence Olfactory Necklace, Bedside Olfaction Device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Terminated Not applicable Interventional Results available

Machine Learning Neurofeedback for PTSD

NCT03482466
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Neurofeedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Sep 2, 2026, 6:33 AM EDT
Active, not recruiting Not applicable Interventional

Neurofeedback to Improve Working Memory in Mild Cognitive Impairment

NCT04566900
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Neurofeedback, Placebo
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Neural Disorders

NCT02761707
View directory record Official record
Conditions
Parkinson's Disease, Alzheimer's Disease, Progressive Supranuclear Palsy, Essential Tremor, Multiple System Atrophy, Drug Induced Parkinson's Disease, Diffuse Lewy Body Disease, Myasthenia Gravis, Spinal Cord Injuries
Interventions
Electrical Brainstem Responses, Olfactory Tests, Visual Deprivation, Peripheral Nerve Stimulation
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

EEG Alpha/Theta Neurofeedback to Reduce Trait Anxiety

NCT02964520
View directory record Official record
Conditions
Anxiety
Interventions
Neurofeedback training, Sham comparator: Sham neurofeedback training
Behavioral
Lead sponsor
University of Hartford
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Sep 2, 2026, 6:33 AM EDT
Not listed Early Phase 1 Interventional

Brain Activity in People With Chronic Neuropathic Pain and Spinal Cord Injury

NCT04386174
View directory record Official record
Conditions
Neuropathic Pain, Spinal Cord Injury
Interventions
Neurofeedback
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of Computer-based Attention-training Systems in Children With Attention Deficit Hyperactivity Disorder (ADHD)

NCT00956605
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Computer attention training systems for children with ADHD
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
10 Years to 15 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2009 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Computer Attention Training Programs in Schools for Children With Attention Deficit/Hyperactivity Disorder

NCT01583829
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Neurofeedback, Cognitive Training, Waitlist Control
Behavioral · Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
6 Years to 12 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases

NCT02079610
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
real-time fMRI neurofeedback: Amygdala, real-time fMRI neurofeedback: HIPS
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 2, 2026, 6:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

NCT07122739
View directory record Official record
Conditions
Healthy
Interventions
Active Real-time fMRI Neurofeedback, Sham Real-time fMRI neurofeedback
Behavioral
Lead sponsor
Trustees of Princeton University
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Stress and Neurofeedback in Anorexia Nervosa

NCT05834816
View directory record Official record
Conditions
Anorexia Nervosa, Atypical Anorexia Nervosa
Interventions
Negative Affect Task
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Rt-fMRI Neurofeedback and AH in Schizophrenia

NCT03504579
View directory record Official record
Conditions
Audio Visual Hallucinations, Neurofeedback, Schizophrenia, Superior Temporal Gyrus
Interventions
rt-fMRI neurofeedback
Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Brockton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional

HRV Biofeedback in Fibromyalgia

NCT00222274
View directory record Official record
Conditions
Fibromyalgia Syndrome
Interventions
RSA Biofeedback, EEG Biofeedback Condition
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 8, 2015 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder

NCT04306341
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
real time fMRI neurofeedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder

NCT03535129
View directory record Official record
Conditions
Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
Interventions
Real time fMRI neurofeedback
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Recruiting Not applicable Interventional

A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder

NCT05621538
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Realtime fMRI Neurofeedback - Active, TMS - Active, Realtime fMRI Neurofeedback - Yoked Sham, TMS - Sham
Behavioral · Device
Lead sponsor
Auburn University
Other
Eligibility
19 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders

NCT07737652
View directory record Official record
Conditions
Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
Interventions
Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder
Device · Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Terminated Not applicable Interventional Results available

Neurofeedback in Individuals With Substance Use Disorders

NCT04188288
View directory record Official record
Conditions
Opioid-Related Disorders
Interventions
Experimental feedback, Control feedback, fMRI
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dyadic Neurofeedback for Development of Healthy Emotion Regulation in Youth

NCT05472545
View directory record Official record
Conditions
Emotional Regulation
Interventions
Neurofeedback
Behavioral
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
14 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

A Novel fNIRS Neurofeedback Intervention for Enhancement of Working Memory in Attention Deficit Hyperactivity Disorder (ADHD)

NCT04002167
View directory record Official record
Conditions
ADHD
Interventions
Neurofeedback, Cognitive training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 11 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 2, 2026, 6:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EEG-Guided Binaural Beat Audio to Reduce Performance-Related Stress and Improve Cognition

NCT07407426
View directory record Official record
Conditions
Cognitive Abilities, Performance, Stress, Cognitive Performance
Interventions
EEG-guided binaural beat audio, Non-binaural audio intervention
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Pain Management Using Mobile Technology in Veterans With PTSD and TBI

NCT02237885
View directory record Official record
Conditions
Chronic Pain, Posttraumatic Stress Disorders, Traumatic Brain Injury
Interventions
NeuroSky MindWave Mobile
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 2, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Neurofeedback Enhanced Cognitive Reappraisal Training

NCT06132659
View directory record Official record
Conditions
Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
Interventions
Functional magnetic resonance imaging (fMRI) with Veritable-NF, fMRI with Sham-NF
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 2, 2026, 6:33 AM EDT