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ClinicalTrials.gov public records Last synced Nov 11, 2026, 5:14 PM EST

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Showing 25–48 of 51 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: EGCG Clear all

Conditions: Healthy
Interventions: Thearubigins, Theaflavins, Procyanidin Dimer B2 (DB2), (-)-Epigallocatechin-3-O-gallate (EGCG), (-)-Epicatechin-3-O-gallate (ECG), (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), Control; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 25 Years to 60 Years · Male only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Davis, California

Conditions: Advanced Colorectal Adenomas, Adenocarcinoma of the Colon, Stage I Colon Cancer, Stage II Colon Cancer, Stage III Colon Cancer
Interventions: defined green tea catechin extract, placebo, questionnaire administration, laboratory biomarker analysis; Drug · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 3
States / cities: Chicago, Illinois • Hines, Illinois • Rochester, Minnesota

Conditions: Multiple Sclerosis
Interventions: Polyphenon E; Drug
Lead sponsor: Louisiana State University Health Sciences Center in New Orleans; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Cirrhosis
Interventions: Biopsy, Biospecimen Collection, Computed Tomography, Defined Green Tea Catechin Extract, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Pharmacological Study, Questionnaire Administration, Ultrasound; Procedure · Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Multiple Myeloma and Plasma Cell Neoplasm, Precancerous Condition
Interventions: defined green tea catechin extract, gene expression analysis, protein analysis, laboratory biomarker analysis; Dietary Supplement · Genetic · Other
Lead sponsor: Barbara Ann Karmanos Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Precancerous Condition, Prostate Cancer
Interventions: green tea catechin extract, fish oil, placebo; Dietary Supplement · Other
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 21 Years to 120 Years · Male only
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2013
U.S. locations: 3
States / cities: Portland, Oregon

Conditions: Impulsivity, Alcohol Consumption
Interventions: Phospholean, Placebo; Dietary Supplement
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Postprandial Glucose, GLP-1 Concentration, Satiety
Interventions: Sucrose Beverage, Glucose + Fructose beverage, Sucrose with EGCG Beverage, Glucose-Fructose with EGCG Beverage; Dietary Supplement
Lead sponsor: Purdue University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Healthy
Interventions: Green Tea, Placebo; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2012
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Energy Expenditure, Appetite
Interventions: Medifast Metabolism-boosting Beverages; Other
Lead sponsor: Medifast, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Owings Mills, Maryland

Conditions: Leiomyoma, Uterine
Interventions: Green Tea Extract, Placebo; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 4
States / cities: New Haven, Connecticut • Chicago, Illinois • Baltimore, Maryland

Conditions: Appetitive Behavior, Obesity, Diabetes Mellitus, Type 2
Interventions: Rice flour, Alternanoligosaccharide 15, Inulin, Waxy potato starch, Waxy potato starch + epigallocatechin gallate (EGCG), Chickpea flour + epigallocatechin gallate (EGCG); Other
Lead sponsor: Purdue University; Other
Eligibility: 22 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Atherosclerosis
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Hypertension, Obesity, Type 2 Diabetes, Insulin Resistance
Interventions: EGCG; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 21 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Frailty, Inflammation
Interventions: Epigallocatechin-3-Gallate (EGCG) plus Ascorbic Acid (Vitamin C); Drug
Lead sponsor: University of Rochester; Other
Eligibility: 65 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Estrogen Receptor-negative Breast Cancer, Progesterone Receptor-negative Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer
Interventions: placebo, quality-of-life assessment, questionnaire administration, laboratory biomarker analysis, defined green tea catechin extract; Other · Procedure · Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 21 Years to 65 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 4
States / cities: New York, New York • Houston, Texas

Conditions: Multiple Sclerosis
Interventions: 95% Pure ECGC capsules 200mg, Placebo Comparator:; Drug
Lead sponsor: Louisiana State University Health Sciences Center in New Orleans; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Barrett Esophagus
Interventions: placebo, defined green tea catechin extract; Other · Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 3
States / cities: New York, New York • Houston, Texas

Conditions: Prostatic Hyperplasia
Interventions: Polyphenon E, Placebo; Drug
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 30 Years to 80 Years · Male only
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2018
U.S. locations: 10
States / cities: Gainesville, Florida • Jacksonville, Florida • Lakeland, Florida + 5 more

Conditions: Cirrhosis, Liver
Interventions: Epigallocatechin gallate (EGCG), Placebo; Drug · Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Uterine Fibroids
Interventions: Epigallocatechin gallate (EGCG), Clomiphene Citrate, Letrozole; Dietary Supplement · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage II Prostate Cancer
Interventions: defined green tea catechin extract, placebo, immunohistochemistry staining method, immunoenzyme technique, laboratory biomarker analysis, biopsy, mass spectrometry, high performance liquid chromatography; Dietary Supplement · Drug · Other + 1 more
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older · Male only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Cervical Cancer, Cervical Intraepithelial Neoplasia Grade 1, Human Papilloma Virus Infection
Interventions: placebo, defined green tea catechin extract, laboratory biomarker analysis; Drug · Dietary Supplement · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Idiopathic Pulmonary Fibrosis
Interventions: Epigallocatechin-3-gallate (EGCG); Drug
Lead sponsor: Hal Chapman; Other
Eligibility: 40 Years to 70 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: San Francisco, California

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Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans

Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer

Safety of Polyphenon E in Multiple Sclerosis Pilot Study

Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis

Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma

Fish Oil and Green Tea Extract in Preventing Prostate Cancer in Patients Who Are at Risk for Developing Prostate Cancer

The Gut-brain Axis in Food Reward and Alcohol Consumption

Postprandial Glycemic and GLP-1 Responses to Modified Full-sugar Drinks

Green Tea and Ultraviolet Light-induced Skin Damage

Evaluation of Metabolism-Boosting Beverages

FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea

Impact of Slowly Digestible Carbohydrates on the Gut-brain Axis

Effects of EGCG-Enhanced Extra Virgin Olive Oil on Endothelial Function

Effect of EGCG on the Body's Response to Insulin

Reducing Frailty for Older Cancer Survivors Using Supplements

Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer

Safety and Brain Protection Effects of the Green Tea Extract Theaphenon 95% (95% Pure EGCG) in Multiple Sclerosis

Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus

Study of Polyphenon E in Men With High-grade Prostatic Intraepithelial Neoplasia

EGCG for Hepatocellular Carcinoma Chemoprevention

Pharmacokinetics and Hepatic Safety of EGCG

Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate

Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial Neoplasia

Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis.