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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: EHR Nudge Clear all
Completed Not applicable Interventional

Improving Inpatient Screening for Hepatitis C

NCT04525690
View directory record Official record
Conditions
Hepatitis C
Interventions
Nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
7,634 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Sep 6, 2026, 2:51 PM EDT
Enrolling by invitation Not applicable Interventional

Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

NCT07636187
View directory record Official record
Conditions
Behavior, Health
Interventions
Pre-visit and post-visit patient messaging, Default pended order, EHR communication
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
16,416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional

A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients

NCT05502861
View directory record Official record
Conditions
Palliative Care
Interventions
Generalist + Specialist palliative care, Pre-Intervention phase
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
18,884 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT06377033
View directory record Official record
Conditions
Genetic Predisposition, Paraganglioma, Pheochromocytoma, ALS, Parkinson Disease, Polyneuropathies, Frontotemporal Dementia, Alzheimer Disease, Cardiomyopathy Non-ischemic, Thoracic Aortic Aneurysm
Interventions
Behavioral nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

Increasing Screening for Cancer Using EHR-Nudges

NCT06177795
View directory record Official record
Conditions
Breast Cancer
Interventions
Post-visit patient text messaging, Default pended order, High risk bidirectional post-visit text messaging
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
40 Years to 74 Years · Female only
Enrollment
21,123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Cleveland, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Clinical Decision Support to Improve System Naloxone Co-prescribing

NCT06271668
View directory record Official record
Conditions
Medication Abuse, Harm Reduction, Opioid Overdose, Opioid Prescribing
Interventions
Naloxone Co-prescribing Clinical Decision Support (CDS)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 89 Years
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Active, not recruiting Not applicable Interventional

Centralized Prescribing for Statins

NCT05537064
View directory record Official record
Conditions
Hyperlipidemias
Interventions
Non-visit Based Intervention, Visit-Based Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 75 Years
Enrollment
1,950 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

Behavioral Economics to Improve Flu Vaccination Using EHR Nudges

NCT06057727
View directory record Official record
Conditions
Behavior, Health, Flu, Flu Vaccination
Interventions
Pre-visit patient text messaging, Default pended order, Monthly peer comparison feedback, High risk bidirectional pre-visit text messaging
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
80,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Current Opioid-User Population

NCT04601480
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Abuse
Interventions
Choice Architecture Nudge, PMP Integration & Nudge
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Increasing Adherence to Lung Cancer Screening

NCT05832008
View directory record Official record
Conditions
Lung Cancer, Adherence, Patient
Interventions
Patient Nudge, Clinician Nudge
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 80 Years
Enrollment
825 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

NCT05721326
View directory record Official record
Conditions
Genetic Predisposition to Disease, Breast Cancer Female, Ovarian Cancer, Hereditary Breast and Ovarian Cancer, Hereditary Cancer Syndrome, Hereditary Diseases, Gene Mutation-Related Cancer
Interventions
Sequential EHR Communications
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
25 Years to 100 Years · Female only
Enrollment
1,283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

Evaluating a Our Practice Advisory (OPA) to Optimize Hemoglobin A1c (A1c) and Thyroid-Stimulating Hormone (TSH) Test Orders

NCT06993805
View directory record Official record
Conditions
Physician Workflow, Resource Utilization
Interventions
OPA
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges

NCT04477304
View directory record Official record
Conditions
Opioid Abuse, Unspecified
Interventions
Opioid Naive, OR, At-risk for long-term use, OR, Long-term opioid recipient
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
555 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Withdrawn Not applicable Interventional

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase

NCT03791580
View directory record Official record
Conditions
Fall, Congestive Heart Failure, Chronic Kidney Failure, Adverse Drug Event
Interventions
Commitment nudge, Justification nudge
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

Behavioral Economics to Improve Flu Vaccination Using EHR Nudges Replication

NCT06626321
View directory record Official record
Conditions
Behavior, Health, Flu, Flu Vaccination
Interventions
Pre-visit patient text messaging, Default pended order, Monthly peer comparison feedback, High risk bidirectional pre-visit text messaging
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
26,248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers

NCT04601506
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Abuse
Interventions
Choice Architecture Nudge, PMP Integration & Nudge
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population

NCT04601493
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Abuse
Interventions
Choice Architecture Nudge, PMP Integration & Nudge
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
631 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 25, 2024 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of a Behavioral Economic Intervention to Reduce Antibiotic Prescription for Upper Respiratory Infections

NCT03464279
View directory record Official record
Conditions
Antibiotics, Upper Respiratory Infections, Safety-Net Hospitals, Behavioral Economics, Choosing Wisely
Interventions
Nudge using Behavioral Economic Interventions, Standard Practices to Reduce Health System Antibiotic Prescription
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Sep 6, 2026, 2:51 PM EDT
Completed No phase listed Observational

Using Nudges to Implement Comparative Effectiveness

NCT01575171
View directory record Official record
Conditions
Hypercholesterolemia
Interventions
Nudge
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2015 · Synced Sep 6, 2026, 2:51 PM EDT
Not yet recruiting Not applicable Interventional

Scaling Out S.A.F.E. Firearm Across Two Health Systems as a Universal Suicide Prevention Strategy (SCALE ASPIRE)

NCT07009314
View directory record Official record
Conditions
Suicide
Interventions
Implementation package (training, facilitation, electronic health record nudge)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
5,442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

A Patient-facing Tool to Reduce Opioid-Psychotropic Polypharmacy in People Living With Dementia (PLWD)

NCT05628181
View directory record Official record
Conditions
Polypharmacy, Dementia
Interventions
Educational nudge intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Ann Arbor, Michigan • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 6, 2026, 2:51 PM EDT
Active, not recruiting Not applicable Interventional

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial

NCT05656560
View directory record Official record
Conditions
Polypharmacy
Interventions
Clinical decision support (CDS)-Commitment nudge, Clinician education, Clinical decision support (CDS)-Justification nudge
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
786 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 6, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing Vaccine Uptake Among Veterans at the Atlanta VA Health Care System

NCT03950986
View directory record Official record
Conditions
Influenza, Tetanus, Diphtheria, Pertussis, Pneumonia
Interventions
Modified clinical reminders
Other
Lead sponsor
Atlanta VA Medical Center
Federal
Eligibility
Not listed
Enrollment
67,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Sep 6, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

NCT06806163
View directory record Official record
Conditions
Opioid Overdose, Opioid Use, Opioid Use Disorder, Opioids
Interventions
EHR-Embedded Elevated-Risk Flag, EHR-Embedded Elevated-Risk Flag with Behavioral Nudges, Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 6, 2026, 2:51 PM EDT