- Conditions
- Arterial Stiffness, White Matter Lesions, Cognitive Decline
- Interventions
- S-equol, Placebo
- Drug
- Lead sponsor
- Akira Sekikawa
- Other
- Eligibility
- 65 Years to 85 Years
- Enrollment
- 369 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 3
- States / cities
- Atlanta, Georgia • Winston-Salem, North Carolina • Pittsburgh, Pennsylvania
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- Conditions
- Perimenopause-Related Depression
- Interventions
- Estradiol, ER Beta Agonist, Placebo, Provera
- Drug · Other
- Lead sponsor
- National Institute of Mental Health (NIMH)
- NIH
- Eligibility
- 45 Years to 65 Years · Female only
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Schizophrenia
- Interventions
- LY500307 150mg, LY500307 75mg, Placebo, LY500307 25mg
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 65 Years · Male only
- Enrollment
- 95 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 4
- States / cities
- Indianapolis, Indiana