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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Early Weight-Bearing Clear all
Not yet recruiting Not applicable Interventional

Weight Bearing After Pelvis and Acetabulum Fracture Fixation

NCT07189156
View directory record Official record
Conditions
Pelvis Fractures, Acetabulum Fractures
Interventions
Immediate Weight Bearing Pelvis, Delayed Weight Bearing Pelvis, Immediate Weight Bearing Acetabulum, Delayed Weight Bearing Acetabulum
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Birmingham, Alabama • Colton, California • Indianapolis, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Early Weight Bearing for Unstable Ankle Fractures Undergoing Operative Stabilization

NCT02779244
View directory record Official record
Conditions
Ankle Fracture
Interventions
Early Weight bearing + Cam Boot, Non-Weight Bearing + Cam Boot
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures

NCT04028414
View directory record Official record
Conditions
Rehabilitation
Interventions
Early Weight Bearing
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years and older
Enrollment
435 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
17
States / cities
Birmingham, Alabama • San Francisco, California • Indianapolis, Indiana + 14 more
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Enrolling by invitation No phase listed Observational

Early Weight Bearing in Unicondylar Tibial Plateau Fractures

NCT06389240
View directory record Official record
Conditions
Early Mobilization
Interventions
6 weeks post-operatively early weight bearing, 10 weeks post-operatively weight bearing (standard of care)
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Timeline
2022 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Early Motion Following Carpal Tunnel Release

NCT00845325
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Group One, Control Group Two
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Early Weight Bearing on Supracondylar Distal Femur Fractures in Elderly Patients

NCT02475941
View directory record Official record
Conditions
Distal Femur Fractures
Interventions
Non Weight bearing, Early Weight Bearing
Other
Lead sponsor
St. Louis University
Other
Eligibility
64 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
6
States / cities
Atlanta, Georgia • St Louis, Missouri • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Sep 13, 2026, 8:22 AM EDT
Terminated No phase listed Observational

Early Weight-Bearing After Lapidus Arthrodesis

NCT03257540
View directory record Official record
Conditions
Arthrodesis, Bunion, Hallux Valgus
Interventions
Small Bone Intramedullary Nail
Device
Lead sponsor
Paragon 28
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Santa Rosa, California • Fort Collins, Colorado • Atlantis, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Sep 13, 2026, 8:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Early Weight-Bearing After the Lapiplasty Mini-Incision Procedure (Mini3D)

NCT05082012
View directory record Official record
Conditions
Hallux Valgus, Bunion
Interventions
Treatment of Hallux Valgus
Device
Lead sponsor
Treace Medical Concepts, Inc.
Industry
Eligibility
14 Years to 58 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
10
States / cities
Decatur, Alabama • Hartselle, Alabama • Scottsdale, Arizona + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Recruiting Phase 1 Interventional

UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

NCT06737380
View directory record Official record
Conditions
SLE, Lupus, Systemic Lupus Erthematosus, Systemic Lupus Erythematosus, Systemic Lupus Erythematosus (SLE)
Interventions
Physical examination, Electrocardiogram, SF-36 questionnaire, Clinical laboratory evaluations - Serology, Clinical laboratory evaluations - Biochemistry, Clinical laboratory evaluations - Hematology, Pregnancy Test, Urinalysis, SLE activity evaluation, SLE biomarker profiling, Cytokines and chemokine profiling, single dose of UC-MSCs, PROMIS instruments
Diagnostic Test · Other · Biological
Lead sponsor
LiveKidney.Bio
Industry
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 13, 2026, 8:22 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Weight Bearing for Fibular Fractures

NCT04872296
View directory record Official record
Conditions
Fibula Fracture
Interventions
Controlled Ankle Motion (CAM) boot, Physical Therapy
Device · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Sep 13, 2026, 8:22 AM EDT
Terminated No phase listed Observational

Early Standardized Weight Bearing Utilizing Immersion Therapy Following Periarticular Lower Extremity Fractures

NCT01457326
View directory record Official record
Conditions
Lower Extremity Periarticular Fractures
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Dose of Early Therapeutic Mobility: Does Type or Frequency Matter?

NCT00999011
View directory record Official record
Conditions
Critical Illness
Interventions
once daily mobility activity, twice daily mobility activity
Procedure
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 99 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Achilles Tendon Lengthening With Traditional vs. Accelerated Rehab

NCT04050748
View directory record Official record
Conditions
Achilles Tendon Rupture
Interventions
Achilles tendon repair
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
Not listed
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Sep 13, 2026, 8:22 AM EDT
Active, not recruiting Not applicable Interventional

STaR Trial: Multiple Ligament Knee Injuries

NCT03543098
View directory record Official record
Conditions
Knee Dislocations, Multiple Ligament Knee Injuries
Interventions
Early Surgery, Delayed Surgery, Early Rehab, Delayed Rehab
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 55 Years
Enrollment
690 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fibulink Syndesmosis Repair System With Early Full-Weight Bearing

NCT06085586
View directory record Official record
Conditions
Ankle Fractures, Bimalleolar Fractures, Syndesmotic Injuries, Bimalleolar Equivalent Fracture, Maisonneuve Fracture, Trimalleolar Fractures, Ankle Dislocation
Interventions
Early Weight Bearing, Normal Weight Bearing
Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
22 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Enrolling by invitation Not applicable Interventional

Immediate Weightbearing vs Delayed Weightbearing

NCT05595148
View directory record Official record
Conditions
Rehabilitation
Interventions
Immediate WBAT, No Intervention: Delayed WBAT
Procedure · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland • Cheverly, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Prosthetic Arms for Amputee: A Better Fit and More Functionality

NCT05990062
View directory record Official record
Conditions
Amputation, Surgical
Interventions
K-Socket-Harness
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 13, 2026, 8:22 AM EDT
Recruiting Not applicable Interventional

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

NCT04875052
View directory record Official record
Conditions
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
Interventions
Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 35 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 13, 2026, 8:22 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Mobilization Following Volar Locking Plate Fixation of Distal Radius Fractures

NCT05033938
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Early Mobilization Protocol, Late Mobilization Protocol
Procedure
Lead sponsor
Robert Wood Johnson Barnabas Health
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 13, 2026, 8:22 AM EDT
Terminated Not applicable Interventional

Immediate Weight-bearing Verses Non-Weight-bearing After Foot & Ankle Surgery

NCT03996707
View directory record Official record
Conditions
Foot and Ankle Surgery
Interventions
Weight Bearing, Strict non-weight bearing
Other
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Clairton, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Syndesmosis Ankle Study

NCT03970603
View directory record Official record
Conditions
Syndesmotic Disruption, Weight-bearing Status
Interventions
Early Weight-Bearing, Delayed/Late Weight-Bearing
Other
Lead sponsor
Kyle Schweser MD
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional Results available

Improving Rehabilitation Outcomes After Total Hip Arthroplasty

NCT02920866
View directory record Official record
Conditions
Total Hip Arthroplasty, Osteoarthritis
Interventions
Functional Strength Integration (FSI), Control Group (CON)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 13, 2026, 8:22 AM EDT
Completed Not applicable Interventional

Study of Tibial Shaft Fractures in Children

NCT01238523
View directory record Official record
Conditions
Tibial Shaft Fractures in Children
Interventions
Long leg cast in full extension, Long leg cast with 45 degrees of flexion
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 14 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Sep 13, 2026, 8:22 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

TAR 2 Weeks vs 6 Weeks Post-Operative Weight-Bearing

NCT04709861
View directory record Official record
Conditions
Ankle Osteoarthritis
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Sep 13, 2026, 8:22 AM EDT