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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Early language intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Novel Parent Education Program for Early Intervention

NCT04266717
View directory record Official record
Conditions
Preterm Infant, Full-term Infant
Interventions
Baby Play Intervention, Milestone Education
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
1 Month to 1 Year
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Early Speech With One-Way Speaking Valve in Tracheostomy Patients

NCT03008174
View directory record Official record
Conditions
Respiratory Failure, Speech, Aphonia
Interventions
Early one-way speaking valve (OWSV) assessment
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Sep 11, 2026, 4:50 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid Telehealth

NCT05743439
View directory record Official record
Conditions
Intellectual Disability, Speech and Language Disorder
Interventions
Early Augmentative and Alternative Communication (AAC) Intervention
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
24 Months and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families

NCT03307057
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition, Usual Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
6 Months to 6 Months
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 11, 2026, 4:50 PM EDT
Terminated Not applicable Interventional

Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care

NCT05456139
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Treatment as Usual, Early Social Interaction Mobile Coaching (ESI-MC)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Months to 20 Months
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Los Angeles, California • Tallahassee, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Randomized Trial of LENA Home in A Home Visiting Program

NCT04031326
View directory record Official record
Conditions
Parent-Child Relations, Language Development
Interventions
LENA Home
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Months to 9 Months
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 8, 2021 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Grounded Early Substance Use Prevention for American Indian Families

NCT02383225
View directory record Official record
Conditions
Substance Use
Interventions
Lakota Language enhancement, Facebook Supplement, Substance Use Resistance Skills
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 85 Years
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

EMT en Español for Spanish-speaking Toddlers With Language Delays

NCT04066049
View directory record Official record
Conditions
Language Development Disorders
Interventions
EMT en Español
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
30 Months to 36 Months
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Delivering EMT Via Telehealth to Children and Families

NCT04604821
View directory record Official record
Conditions
Language Impairment
Interventions
Enhanced Milieu Teaching, Parent Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Months to 36 Months
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects on Children and Parents of Educating Parents About Ways to Play With Babies

NCT05259423
View directory record Official record
Conditions
Infant Development, Developmental Delay
Interventions
Enriched Education Program, Typical Education Program
Other
Lead sponsor
University of Delaware
Other
Eligibility
1 Month to 24 Months
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Accountability for Care Through Undoing Racism & Equity for Moms

NCT05484804
View directory record Official record
Conditions
Pregnancy Related, Maternal Health, Maternal Mortality, Low Birthweight, Racism, Implicit Bias
Interventions
Data Accountability and Transparency, Community-Based Doula (CBD) Support
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 99 Years · Female only
Enrollment
60,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Coaching in Early Development Project

NCT06347666
View directory record Official record
Conditions
Developmental Delay
Interventions
Caregiver coaching
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
12 Months to 6 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Communication in Autism Network

NCT01018407
View directory record Official record
Conditions
Autism
Interventions
Discrete Trial Training, Interpersonal Developmental Approach
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
33 Months to 54 Months
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
3
States / cities
Los Angeles, California • Baltimore, Maryland • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maximizing Language Development in Children With Hearing Loss

NCT01963468
View directory record Official record
Conditions
Hearing Loss
Interventions
Early language intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
6 Months to 18 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Newborn Implementation

NCT03366831
View directory record Official record
Conditions
Language Development
Interventions
Thirty Million Words Initiative Newborn Intervention
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
2,701 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Pensacola, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 11, 2026, 4:50 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Duet 2.0 Starting the Conversation: A New Intervention Model to Stimulate Language Growth in Underserved Populations

NCT04692519
View directory record Official record
Conditions
Language Development, Language, Child, Early Intervention
Interventions
Duet Language Intervention Modules
Behavioral
Lead sponsor
Temple University
Other
Eligibility
12 Months and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Development and Pilot Testing of a Novel Preschool Executive Function Curriculum

NCT05135728
View directory record Official record
Conditions
Executive Dysfunction
Interventions
Unstuck and On Target: Preschool
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
3 Years to 6 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 11, 2026, 4:50 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Training Early Social Language in Autism

NCT03427138
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Jasper, Parent Education
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Months to 59 Months
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Evaluating the Efficacy of Pathways Parent-Mediated Early Autism Intervention on Social Attention and Language

NCT05604326
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Pathways Intervention, Parent Education Intervention (PEI)
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
12 Months to 42 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Supporting Early Learning Study

NCT04107506
View directory record Official record
Conditions
Child Behavior, Parent-Child Relations
Interventions
Filming Interactions to Nurture Development, The Healthy Toddler Program
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
12 Months and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 11, 2026, 4:50 PM EDT
Not yet recruiting Not applicable Interventional

Opt-In Early Pilot Study

NCT06908187
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Opt-In Early Latinx intervention, Opt-In Early Rural Intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
15 Months and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Hartford, Connecticut • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 11, 2026, 4:50 PM EDT
Active, not recruiting Not applicable Interventional

Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

NCT06525818
View directory record Official record
Conditions
Feeding Tube, Children With Medical Complexity, Tracheostomy, Feeding Disorder, Infancy or Early Childhood
Interventions
Tube weaning therapy intervention, Feeding Group
Other
Lead sponsor
University of Chicago
Other
Eligibility
Up to 3 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 11, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Delivering Early Intervention to Children With Down Syndrome

NCT03935620
View directory record Official record
Conditions
Down Syndrome
Interventions
Enhanced Milieu teaching
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Months to 36 Months
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 11, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional

Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays

NCT07227974
View directory record Official record
Conditions
Developmental Delays
Interventions
Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
12 Months to 31 Months
Enrollment
1,269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 11, 2026, 4:50 PM EDT