Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 5, 2026, 12:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–5 of 5 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Tricuspid Valve Regurgitation, Tricuspid Valve Disease, Cardiovascular Diseases (CVD), Heart Valve Diseases, Tricuspid Valve Insufficiency, Severe Heart Valve Disease, Randomized Controlled Trial (RCT), Symptomatic Tricuspid Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement (TTVR) with VDyne System, Transcatheter Tricuspid Valve Replacement (TTVR) with Edwards EVOQUE System
Device
Lead sponsor
VDyne, Inc.
Industry
Eligibility
18 Years and older
Enrollment
730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
Minneapolis, Minnesota
Active, not recruiting Not applicable Interventional Results available

2019-06 TRISCEND Study

NCT04221490
Conditions
Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
14
States / cities
Los Angeles, California • Stanford, California • Atlanta, Georgia + 9 more
Conditions
Severe Tricuspid Regurgitation
Interventions
Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System, Edwards EVOQUE Tricuspid Valve Replacement (TTVR) System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
1,186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2041
U.S. locations
4
States / cities
Phoenix, Arizona • Thousand Oaks, California • Minneapolis, Minnesota + 1 more
Active, not recruiting Not applicable Interventional

TRISCEND II Pivotal Trial

NCT04482062
Conditions
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
Interventions
Edwards EVOQUE System, Optimal Medical Therapy
Device · Drug
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
55
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 41 more
Active, not recruiting Not applicable Interventional

Edwards EVOQUE Eos MISCEND Study

NCT02718001
Conditions
Mitral Valve Regurgitation (Degenerative or Functional)
Interventions
Edwards EVOQUE Eos Mitral Valve Replacement System
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2033
U.S. locations
16
States / cities
Burlingame, California • Los Angeles, California • San Francisco, California + 13 more