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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Terminated Phase 1 Interventional

Assessment of the Safety and Effectiveness of Cortical Stimulation in Subjects With Major Depressive Disorder

NCT00380042
View directory record Official record
Conditions
Depression, Depressive Disorder
Interventions
Cortical Stimulation, Sham
Device
Lead sponsor
Northstar Neuroscience
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 30, 2009 · Synced Sep 20, 2026, 11:20 AM EDT
Withdrawn Not applicable Interventional

Repetitive Transcranial Magnetic Stimulation (rTMS) Self-Referential Processing (rTMS-SRP)

NCT04068857
View directory record Official record
Conditions
Schizophrenia, Schizo Affective Disorder
Interventions
rTMS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

NCT05823740
View directory record Official record
Conditions
Cancer, Malignant Neoplasm
Interventions
Bioelectrical impedance Analysis (BIA), D3-Creatine Dilution (D3Cr), 6-Minute Walk Test (6MWT), Timed Up and Go (TUG), 30-second Sit-to-Stand (STS), Hand Grip Strength (GS), PBTL p16 expression, CT, MR and PET Imaging
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
8 Years to 21 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Electrical Stimulation of Human Myocytes in Microgravity

NCT03665051
View directory record Official record
Conditions
Sarcopenia
Interventions
Muscle Tissue Biopsy, Maximal Oxygen Consumption (V02max)
Procedure · Other
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
20 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 20, 2026, 11:20 AM EDT
Recruiting No phase listed Observational

ESIS in Pediatric DRE

NCT05469373
View directory record Official record
Conditions
Epilepsy
Interventions
Not listed
Lead sponsor
Sarah Katie Ihnen
Other
Eligibility
1 Year to 30 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 20, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study

NCT07768670
View directory record Official record
Conditions
Feasibility Studies, Physical Activity, Mental Health (Depression), Anxiety, Quality of Life
Interventions
Fitness app powered by AI and wearable device
Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional

taVNS or TMS or Both for Depression

NCT05725239
View directory record Official record
Conditions
Depression
Interventions
Vagus Nerve Stimulation, Transcranial Magnetic Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Withdrawn No phase listed Observational

Starling/CRRT Observational Study

NCT05729048
View directory record Official record
Conditions
Hemodynamic Monitoring
Interventions
Starling
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 95 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Neuromuscular Electrical Stimulation to Prevent Exercise Resistance

NCT07161648
View directory record Official record
Conditions
Fat Metabolism
Interventions
neuromuscular electrical stimulation
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Pharmacokinetics of Transdermal Metronidazole

NCT05929794
View directory record Official record
Conditions
Healthy
Interventions
Metronidazole 0.75% Topical Gel, Metronidazole 0.75% Topical Cream, Transdermal water loss measurement, Electrical Resistance, Skin color measurement, Micropatch application
Drug · Diagnostic Test · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

NCT03887715
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Vagus Nerve Stimulation (VNS)
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
6,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
101
States / cities
Birmingham, Alabama • Huntsville, Alabama • Burlingame, California + 85 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Active, not recruiting Not applicable Interventional

DBS of the Lateral Habenula in Treatment-Resistant Depression

NCT01798407
View directory record Official record
Conditions
Treatment Resistant Major Depressive Disorder
Interventions
Activa Tremor Control Sys (DBS Implant), Randomized, staggered withdrawal phase
Device · Other
Lead sponsor
Wayne Goodman MD
Other
Eligibility
21 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 20, 2026, 11:20 AM EDT
Completed No phase listed Observational

Improving Brain Stimulation Through Imaging

NCT03851380
View directory record Official record
Conditions
Depression, Depressive Disorder, Treatment-Resistant, COVID Stress, PTSD - Post Traumatic Stress Disorder
Interventions
Psychological / Functional Assessment, Structural and Functional MRI, Transcranial Magnetic Brain Stimulation and MR Image Guidance, Transcranial Electrical Stimulation (tES)
Behavioral · Other · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Combined Application of Electrical Stimulation and Volitional Contractions for Muscle Strengthening and Knee Pain Inhibition (Seated Study)

NCT02802878
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 85 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Sep 20, 2026, 11:20 AM EDT
Completed No phase listed Observational

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

NCT03529045
View directory record Official record
Conditions
Epilepsy, Seizures, Drug Resistant Epilepsy
Interventions
Vagus Nerve Stimulation (VNS) Therapy
Device
Lead sponsor
LivaNova
Industry
Eligibility
Not listed
Enrollment
827 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
19
States / cities
Grand Junction, Colorado • Washington D.C., District of Columbia • Orlando, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury

NCT03854214
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Functional Electric Stimulation cycling, Passive cycling
Device
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Vagal Nerve Stimulation for Treatment Resistant Major Depression

NCT04990687
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
gammaCore™
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Comparing Acupuncture, BioModulator, and Transcutaneous Electrical Nerve Stimulation for Symptomatic Treatment of Chronic Pain.

NCT01752010
View directory record Official record
Conditions
Chronic Pain, Depression, PTSD Symptoms, Sleep
Interventions
Traditional Chinese Acupuncture, Tennant™ Biomodulator Treatment, Transcutaneous electrical nerve stimulation (TENS) Treatment
Other · Device
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Pivotal Trial (D02) of Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depression (TRD)

NCT00533832
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
vagus nerve stimulation (VNS)
Device
Lead sponsor
Cyberonics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 23, 2007 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?

NCT02987621
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
tDCS
Device
Lead sponsor
Colorado State University
Other
Eligibility
30 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Sep 20, 2026, 11:20 AM EDT
Not yet recruiting Not applicable Interventional

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

NCT06898138
View directory record Official record
Conditions
Epilepsy
Interventions
Brain Interchange System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Withdrawn Not applicable Interventional

Vagus Nerve Stimulator for Autism and Other Developmental Disorders

NCT06259201
View directory record Official record
Conditions
Autism Spectrum Disorder, Intellectual Disability, Autonomic Nervous System, Developmental Disability
Interventions
Vagus Nerve Stimulation
Device
Lead sponsor
New York State Institute for Basic Research
Government
Eligibility
12 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
New York, New York • Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer

NCT04411810
View directory record Official record
Conditions
Skin Cancer
Interventions
Nevisense 3.0, Dermlite Cam, Skin biopsy, Barco Demetra
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2024 · Synced Sep 20, 2026, 11:20 AM EDT
Completed Phase 4 Interventional

Comparison of Anodal Transcranial Direct Current Stimulation (t-DCS) and Sham Stimulation in Patients With Treatment-resistant Depression

NCT02141776
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Transcranial direct current stimulation (t-DCS), Sham Controlled Arm
Device · Other
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Sep 20, 2026, 11:20 AM EDT