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ClinicalTrials.gov public records Last synced Oct 7, 2026, 12:10 PM EDT

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Showing 25–48 of 49 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Endobronchial ultrasound (EBUS) Clear all
Completed Not applicable Interventional

Endobronchial Ultrasound Versus Mediastinoscopy in Patients With Non-Small Cell Lung Cancer (NSCLC)

NCT00559611
View directory record Official record
Conditions
Lung Cancer
Interventions
Endobronchial Ultrasound, Mediastinoscopy
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 7, 2026, 12:10 PM EDT
Terminated Not applicable Interventional

Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer

NCT00970645
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
Mediastinoscopy/thoracoscopy, EBUS/EUS
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2011 · Synced Oct 7, 2026, 12:10 PM EDT
Terminated Not applicable Interventional

Surgical Versus Non-surgical Staging of Lung Cancer

NCT01117714
View directory record Official record
Conditions
Lung Cancer
Interventions
Integrated Staging for Early Detection of Metastases in Lung Cancer
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Oct 7, 2026, 12:10 PM EDT
Enrolling by invitation Not applicable Interventional

ROSE for Improved Molecular Marker Testing Via EBUS

NCT04945317
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
ROSE (presence of cytotech) & liquid prep, NO-ROSE (absence of cytotech) & liquid prep, ROSE (presence of cytotech) & tissue clot sample, NO-ROSE (absence of cytotech) & tissue clot sample
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
Chicago, Illinois • Baltimore, Maryland • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 7, 2026, 12:10 PM EDT
Terminated No phase listed Observational

Use of Endobronchial Ultrasound Scope (EBUS) Transducer to Identify Pneumothorax-A Feasibility Study

NCT02907866
View directory record Official record
Conditions
Pneumothorax
Interventions
Ultrasound with EBUS scope and with linear ultrasound probe
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional Results available

Ultrathin Bronchoscope and Radial Endobronchial Ultrasound (R-EBUS) With Fluoroscopy Versus Standard Fiberoptic Bronchoscopy (FB) (P00029233 )

NCT02146131
View directory record Official record
Conditions
Pulmonary Lesions, Pulmonary Nodules, Pulmonary Mass
Interventions
Standard FB with fluoroscopy, R-EBUS with ultrathin bronchoscope
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years and older
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Gainesville, Florida • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced Oct 7, 2026, 12:10 PM EDT
Completed No phase listed Observational

Molecular and Diagnostic Classification of Non-Small Cell Lung Cancer From Fine Needle Aspirates

NCT01630122
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional Results available

Pilot Study of Navigational Bronchoscopy and Transthoracic Needle Biopsy

NCT02109458
View directory record Official record
Conditions
Peripheral Pulmonary Nodules
Interventions
Navigation guided bronchoscopy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 7, 2026, 12:10 PM EDT
Terminated Not applicable Interventional Results available

Needle-Based Confocal Laser Endomicroscopy for Diagnosis of Lung Cancer in Patients With Peripheral Pulmonary Nodules

NCT05556525
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Fluorescein, Image-Guided Needle Confocal Laser Endomicroscopy, Ultrasound-Guided Transbronchial Needle Aspiration
Other · Device · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional Results available

EBUS-Miniforceps Biopsy Specimen Acquisition for PD-L1 Testing in Nonsmall Cell Lung Cancer

NCT04159025
View directory record Official record
Conditions
Non Small Cell Lung Cancer, NSCLC
Interventions
CoreDx Pulmonary Mini-Forceps
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 7, 2026, 12:10 PM EDT
Terminated Not applicable Interventional Results available

Cold Saline Irrigation Before Endobronchial Biopsy

NCT06373224
View directory record Official record
Conditions
Lung Diseases
Interventions
Flush
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 7, 2026, 12:10 PM EDT
Completed No phase listed Observational

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation

NCT01430962
View directory record Official record
Conditions
Mediastinal Lymphadenopathies, Mediastinal Masses, Hilar Lymphadenopathies
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional Results available

CrYobiopsy With Radial UltraSound Guidance

NCT03506295
View directory record Official record
Conditions
Pulmonary Disease
Interventions
Radial Endobronchial Ultrasound Probe, Flouroscopy
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 7, 2026, 12:10 PM EDT
Completed No phase listed Observational

Feasibility of Mobile-CT-Assisted Bronchoscopy for the Diagnosis of Lung Lesion

NCT04995172
View directory record Official record
Conditions
Lung Neoplasm
Interventions
Computed Tomography, Electronic Health Record Review, Endobronchial Ultrasound Bronchoscopy
Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Phase 1 Interventional Results available

Safety of PDT-Photofrin® Prior to Lung Surgery

NCT03344861
View directory record Official record
Conditions
Lung Cancer, Lung Cancer Metastatic
Interventions
Porfimer Sodium, Fiber optic
Drug · Device
Lead sponsor
Concordia Laboratories Inc.
Industry
Eligibility
18 Years to 79 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
8
States / cities
Los Angeles, California • Denver, Colorado • Tampa, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional

Endobronchial Ultrasound-Guided Transbronchial Needle-Aspiration With Suction in Obtaining Samples From Patients With Suspected Nodal Metastatic Lung Cancer

NCT04116970
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Bronchoscopy, Ultrasound-Guided Transbronchial Needle Aspiration
Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional

22-gauge ProCore Needle v. Standard 22-gauge (P00030500)

NCT02154698
View directory record Official record
Conditions
Quantity of Tissue Obtained, Quality of Tissue Obtained, Ease of Use of 22-gauge ProCore EBUS Needles and the Standard 22-gauge Needles
Interventions
22-gauge Standard Needle, 22-gauge ProCore Needle
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
Gainesville, Florida • Baltimore, Maryland • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Oct 7, 2026, 12:10 PM EDT
Withdrawn Phase 2 Interventional

Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer

NCT06943664
View directory record Official record
Conditions
Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Refractory Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
Interventions
Biospecimen Collection, Cemiplimab, Cetuximab Sarotalocan Sodium, Computed Tomography, Electronic Health Record Review, Endobronchial Ultrasound Bronchoscopy, Magnetic Resonance Imaging, Photoimmunotherapy, Positron Emission Tomography, Robotic Bronchoscopy, Video-Assisted Thoracic Surgery
Procedure · Biological · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 7, 2026, 12:10 PM EDT
Withdrawn Not applicable Interventional

NEUWAVE Flexible Probe Study #2

NCT03713099
View directory record Official record
Conditions
Cancer of the Lung, Lung Cancer, Neoplasms, Lung, Carcinoma, Non-Small Cell Lung, Non-Small Cell Lung Cancer, Non-Small Cell Lung Carcinoma
Interventions
Microwave ablation
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Duarte, California • Rochester, Minnesota • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional

Pilot Study to Investigate The Diagnostic Yield and Utility of 22g and 19g Endobronchial Ultrasound Transbronchial Needle Aspirate

NCT03311620
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
Endobronchial ultrasound (EBUS) transbronchial needle aspirate (TBNA)
Procedure
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 7, 2026, 12:10 PM EDT
Recruiting Phase 1Phase 2 Interventional

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

NCT06306638
View directory record Official record
Conditions
Malignant Solid Neoplasm
Interventions
Biospecimen Collection, Computed Tomography, Endobronchial Ultrasound Bronchoscopy, Interstitial Photodynamic Therapy, Palliative Radiation Therapy, Physical Performance Testing, Questionnaire Administration, Verteporfin, Laser: ML7710-PDT
Procedure · Radiation · Other + 2 more
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Buffalo, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

NCT03735095
View directory record Official record
Conditions
Locally Advanced Lung Carcinoma, Non-Small Cell Lung Carcinoma, Small Cell Lung Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Solid Tumor
Interventions
Porfimer Sodium, Ultrasound-Guided Transbronchial Needle-Delivered Interstitial Photodynamic Therapy
Drug · Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 7, 2026, 12:10 PM EDT
Completed Not applicable Interventional

Endobronchial Ultrasound Transbronchial Needle Aspiration Using Needle Suction Versus No Suction

NCT01734980
View directory record Official record
Conditions
Mediastinal Lymphadenopathy, Lung Malignancies
Interventions
Endobronchial Ultrasound
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 7, 2026, 12:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The SEQUENCE Trial

NCT06676956
View directory record Official record
Conditions
Pulmonary Nodules
Interventions
Linear EBUS first, Robotic-assisted bronchoscopy first
Diagnostic Test
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
5
States / cities
Sacramento, California • Chicago, Illinois • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 7, 2026, 12:10 PM EDT