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Showing 1–24 of 89 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Endometrial biopsy Clear all
Completed Not applicable Interventional

Endometrial Injury and in Vitro Fertilization Outcomes

NCT02153814
View directory record Official record
Conditions
Infertility
Interventions
Endometrial Scratch, Sham procedure
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 10, 2026, 12:09 PM EDT
Not listed Not applicable Interventional

Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure

NCT01800513
View directory record Official record
Conditions
Implantation Failure, Infertility
Interventions
Endometrial Biopsy, Sham Procedure
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
18 Years to 37 Years · Female only
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 26, 2013 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ultrasound and Endometrial Hyperplasia

NCT00123188
View directory record Official record
Conditions
Endometrial Hyperplasia
Interventions
Ultrasound and Biopsy
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
45 Years to 75 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 10, 2026, 12:09 PM EDT
Active, not recruiting Phase 1 Interventional

TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer

NCT03955978
View directory record Official record
Conditions
Endometrial Cancer, Cancer of the Endometrium
Interventions
TSR-042, Brachytherapy, Endometrial biopsy, Blood draw for immune response
Drug · Radiation · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 10, 2026, 12:09 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis

NCT05862805
View directory record Official record
Conditions
Menstrual Bleeding, Heavy
Interventions
Sample Collection and Endometrial Biopsy
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 10, 2026, 12:09 PM EDT
Not yet recruiting Phase 2 Interventional

Investigating Pre-Procedural Anxiety and Effect of Analgesia on Intrauterine Device Placement and Endometrial Biopsy

NCT07031206
View directory record Official record
Conditions
Anxiety, Pain
Interventions
Paracervical block- Lidocaine without epinephrine, Benzocaine Gel applied to the cervix, Hydroxyzine Hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 10, 2026, 12:09 PM EDT
Completed Not applicable Interventional

Incidence of Non Receptive Endometrium in Obese Women

NCT02205866
View directory record Official record
Conditions
Infertility
Interventions
Endometrial Receptivity Array analysis of endometrial biopsy
Other
Lead sponsor
Instituto Valenciano de Infertilidad, IVI VALENCIA
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Palo Alto, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Sep 10, 2026, 12:09 PM EDT
Withdrawn Phase 4 Interventional

Misoprostol in Office Hysteroscopy and Endometrial Biopsy

NCT03547778
View directory record Official record
Conditions
Office Hysteroscopy and Endometrial Biopsy
Interventions
Misoprostol 50 mcg pesssary, Placebos
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 70 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Not applicable Interventional

The Effect of Mifepristone on the Expression of Cervical Prostaglandin EP3 Receptors

NCT01224509
View directory record Official record
Conditions
Cervical Prostaglandin EP3 Receptors, Pregnancy
Interventions
Mifepristone, Non-treatment
Drug · Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2010 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Menstrual Phase Endometrial Scratch in IUI Cycles

NCT04641598
View directory record Official record
Conditions
Fertility Disorders, Fertility Issues
Interventions
Endometrial Scratch, Sham procedure
Procedure
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 37 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 10, 2026, 12:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Screening for Endometrial Abnormalities in Overweight and Obese Women

NCT01922778
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Endometrial Biopsy
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
303 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Not applicable Interventional Results available

Lymph Node Mapping in Patients With Newly Diagnosed Endometrial Cancer Undergoing Surgery

NCT01939028
View directory record Official record
Conditions
Stage I Endometrial Carcinoma, Stage II Endometrial Carcinoma, Stage III Endometrial Carcinoma, Stage IV Endometrial Carcinoma
Interventions
lymph node mapping, sentinel lymph node biopsy, isosulfan blue, indocyanine green solution, therapeutic conventional surgery, lymphadenectomy
Procedure · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2020 · Synced Sep 10, 2026, 12:09 PM EDT
Not yet recruiting Not applicable Interventional

Pain Management for In-Office Gynecologic Procedures Using a Risk-Stratification Pain Calculator

NCT07311824
View directory record Official record
Conditions
Pain Management, Patient Satisfaction, Gynecologic Procedures
Interventions
Pain Calculator
Other
Lead sponsor
Carle Foundation Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Champaign, Illinois • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 10, 2026, 12:09 PM EDT
Recruiting Phase 2 Interventional

Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial

NCT07436793
View directory record Official record
Conditions
Endometrial Endometrioid Adenocarcinoma, Endometrial Hyperplasia
Interventions
Biopsy Procedure, Curettage Procedure, Hysterectomy, Megestrol Acetate, Progesterone Only Hormone Replacement Therapy
Procedure · Drug
Lead sponsor
New Mexico Cancer Research Alliance
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
4
States / cities
Iowa City, Iowa • Albuquerque, New Mexico • Salt Lake City, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 10, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

NCT07220239
View directory record Official record
Conditions
Endometrial Cancer, Lynch Syndrome, Screening, Early Detection of Cancer
Interventions
Menstrual cup use
Device
Lead sponsor
Jessica D. St. Laurent, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Not applicable Interventional

Feasibility Study: Accuracy of Biomarker in Detection of Endometrial Cancer

NCT00471120
View directory record Official record
Conditions
Uterine Cancer, Endometrial Cancer
Interventions
P2x7 assay
Other
Lead sponsor
Dick Domanik
Industry
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
5
States / cities
Little Rock, Arkansas • Cleveland, Ohio • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 10, 2026, 12:09 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Endometrial Biopsy in Infertile Patients

NCT00064935
View directory record Official record
Conditions
Infertility
Interventions
Endometrial biopsy
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
25 Years to 39 Years · Female only
Enrollment
880 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
8
States / cities
Birmingham, Alabama • Denver, Colorado • Detroit, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Early Phase 1 Interventional

Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer

NCT04906382
View directory record Official record
Conditions
Lynch Syndrome, Recurrent Endometrial Carcinoma, Recurrent Endometrial Clear Cell Adenocarcinoma, Recurrent Uterine Corpus Carcinosarcoma, Mismatch Repair Deficiency, Recurrent Endometrial Cancer, Metastatic Endometrial Cancer
Interventions
Biopsy, Carboplatin, Paclitaxel, Tislelizumab
Procedure · Drug · Biological
Lead sponsor
Floor Backes, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 10, 2026, 12:09 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

NCT06847685
View directory record Official record
Conditions
Endometriosis, Endometrioma
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
3
States / cities
Athens, Georgia • Baltimore, Maryland • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 10, 2026, 12:09 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

EMLA Cream as Analgesic for Outpatient Gynecological Procedures

NCT05970354
View directory record Official record
Conditions
Pain
Interventions
EMLA Cream, VersaPro Cream Base for Compounding
Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 10, 2026, 12:09 PM EDT
Recruiting No phase listed Observational

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

NCT05059444
View directory record Official record
Conditions
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma, Non-small Cell Lung Cancer, Invasive Breast Carcinoma, Cutaneous Melanoma, Esophageal Carcinoma, Gastroesophageal Junction Carcinoma, Gastric Adenocarcinoma, Pancreatic Adenocarcinoma, Squamous Cell Carcinoma of the Head and Neck, Epithelial Ovarian Carcinoma, Fallopian Tube Carcinoma, Endometrial Carcinoma, Renal Cell Carcinoma, Rectal Adenocarcinoma
Interventions
Guardant Reveal
Diagnostic Test
Lead sponsor
Guardant Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
33
States / cities
Birmingham, Alabama • Chandler, Arizona • Hot Springs, Arkansas + 30 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 10, 2026, 12:09 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Positron Emission Tomography (PET) Imaging Studies With NIS Reporter

NCT02907073
View directory record Official record
Conditions
Myeloma, Endometrial Cancer
Interventions
BF4
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 16, 2019 · Synced Sep 10, 2026, 12:09 PM EDT
Completed Phase 1 Interventional

Safety, Pharmacokinetics (PK) of AKT and MEK Combination

NCT01138085
View directory record Official record
Conditions
Cancer
Interventions
GSK1120212, GSK2141795
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
10
States / cities
Aurora, Colorado • New Haven, Connecticut • Boston, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 10, 2026, 12:09 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of hCG on Receptivity of the Human Endometrium

NCT01786252
View directory record Official record
Conditions
Infertility, Subfertility
Interventions
human chorionic gonadotropin (hCG), Placebo Comparator (for hCG)
Drug
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 34 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Sep 10, 2026, 12:09 PM EDT