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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) Clear all
Completed No phase listed Observational

Pancreatic Cancer Early Detection Program

NCT02206360
View directory record Official record
Conditions
Pancreatic Cancer, Pancreas Cancer, Pancreatic Adenocarcinoma, Familial Pancreatic Cancer, BRCA 1/2, HNPCC, Lynch Syndrome, Hereditary Pancreatitis, FAMMM, Familial Atypical Multiple Mole Melanoma, Peutz Jeghers Syndrome
Interventions
Endoscopic Ultrasound, Magnetic Resonance Imaging (MRI)
Procedure
Lead sponsor
White Plains Hospital
Other
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional

Comparison of Two Fine Needle Biopsy Needles for Solid Pancreatic Masses

NCT02910960
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Acquire EUS Biopsy Device, SharkCore Biopsy System
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional

Evaluation of Multiple Needle Use in EUS-FNA for Pancreatic Cancer

NCT00548626
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Single needle, Multiple needle
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 20, 2015 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated Not applicable Interventional

Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer

NCT00970645
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
Mediastinoscopy/thoracoscopy, EBUS/EUS
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 17, 2011 · Synced Sep 24, 2026, 7:04 PM EDT
Recruiting Not applicable Interventional

Molecular Detection of Advanced Neoplasia in Pancreatic Cysts

NCT03855800
View directory record Official record
Conditions
Pancreas Cyst
Interventions
Blood, stool, pancreatic juice and cyst fluid collection, Pancreatic Surgery, Endoscopy Exam
Diagnostic Test · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional

Endoscopic Ultrasound Guided Liver Biopsy

NCT03307811
View directory record Official record
Conditions
Hepatic Cancer, Hepatic Neoplasm, Hepatic Carcinoma
Interventions
22 gauge needle liver biopsy
Other
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional Results available

Trial Comparing 19 and 25-gauge EUS-FNA Needles

NCT01677312
View directory record Official record
Conditions
Cancer of Pancreas, Pancreatic Neoplasm
Interventions
Pancreatic Biopsy, Histological Samples
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Birmingham, Alabama • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2020 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional

Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients

NCT01916460
View directory record Official record
Conditions
Idiopathic Gastroparesis, Diabetic Gastroparesis
Interventions
Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2021 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional

Trial Comparing 19 and 25G Needles for Fine Needle Aspiration (FNA) of Solid Pancreatic Mass Lesions Greater Than 35mm

NCT01815606
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
biopsy with 19 gauge needle, biopsy with 25 gauge needle
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
19 Years to 89 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Sep 24, 2026, 7:04 PM EDT
Not listed Not applicable Interventional

Randomized Trial for Optimal Number of Passes Required for Molecular Profiling During EUS-FNB of Pancreatic Cancer

NCT05043532
View directory record Official record
Conditions
Pancreatic Cancer, Pancreatic Neoplasms, Adenocarcinoma of the Pancreas
Interventions
2 passes during EUS-guided fine needle biopsy, 3 passes during EUS-guided fine needle biopsy
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional

Evaluating the Safety and Effectiveness of the Flex Robotic System for the Surgical Removal of Colorectal Lesions

NCT05674123
View directory record Official record
Conditions
Colorectal Neoplasm
Interventions
Colonoscopy, Endoscopic Ultrasound, Medical Chart Review, Medical Device Usage and Evaluation, Resection
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated Not applicable Interventional Results available

Endoscopic Ultrasound (EUS) Guided Fine Needle Aspiration (FNA) EUS-FNA of Solid Pancreatic Mass Lesions Using a Novel Corkscrew Technique: a Pilot Study

NCT02116322
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
EUS-FNA with Corkscrew technique, Expect 19 G Flex needle
Procedure · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated No phase listed Observational

Evaluation of Image-guided Brushing of Pancreatic Cyst Wall in Diagnosis of Cystic Pancreatic Tumors

NCT01455311
View directory record Official record
Conditions
Pancreatic Tumors
Interventions
EUS Guided Fine Needle Aspiration, EUS Guided EchoBrush Sampling
Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated Not applicable Interventional

Surgical Versus Non-surgical Staging of Lung Cancer

NCT01117714
View directory record Official record
Conditions
Lung Cancer
Interventions
Integrated Staging for Early Detection of Metastases in Lung Cancer
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Phase 2 Interventional Results available

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

NCT03033225
View directory record Official record
Conditions
Advanced Pancreatic Carcinoma, Locally Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma, Pancreatic Neoplasm, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Pancreatic Carcinoma
Interventions
Endoscopic Ultrasound, Fluorescence Imaging, Photodynamic Therapy, Quality-of-Life Assessment, Questionnaire Administration, Verteporfin
Procedure · Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Phase 3 Interventional

Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses

NCT01085929
View directory record Official record
Conditions
Abscess, Cellulitis
Interventions
Incision and Drainage, Ultrasound Guided Aspiration
Procedure
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2010 · Synced Sep 24, 2026, 7:04 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle

NCT02872831
View directory record Official record
Conditions
Pancreatic Cancer, Lymphadenopathy, Cholangiocarcinoma
Interventions
22G SharkCore™ needle, 22G BNX EUS-FNA Needle
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 24, 2026, 7:04 PM EDT
Recruiting Not applicable Interventional

Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study

NCT05961982
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Chemical Ablation, Computed Tomography, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration, Endoscopic Ultrasound-Guided Radiofrequency Ablation, Magnetic Resonance Cholangiopancreatography, Magnetic Resonance Imaging
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 24, 2026, 7:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

19 Versus 22-Gauge Needle for EUS-LB

NCT02967991
View directory record Official record
Conditions
Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
Interventions
EUS-guided liver biopsy
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Sep 24, 2026, 7:04 PM EDT
Active, not recruiting Phase 2 Interventional

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

NCT06381154
View directory record Official record
Conditions
Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Pancreatic Adenocarcinoma
Interventions
Biopsy, Biospecimen Collection, Computed Tomography, Endoscopic Ultrasound, Fluorouracil, Irinotecan, Leucovorin, Lymph Node Biopsy, Magnetic Resonance Imaging, Oxaliplatin, Pembrolizumab, Photodynamic Therapy, Positron Emission Tomography, Questionnaire Administration, Verteporfin
Procedure · Drug · Biological + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated Phase 3 Interventional

CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts

NCT03085004
View directory record Official record
Conditions
Pancreatic Cyst, EUS-FNA
Interventions
Ethanol, Normal saline, Paclitaxel + Gemcitabine admixture
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Indianapolis, Indiana • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated No phase listed Observational

Comparison of "Wet Suction" Technique to Contemporary "Dry Suction" Technique Using a 22 Gauge Needle for EUS FNA

NCT01720745
View directory record Official record
Conditions
Cancer, Infection, Inflammation, Tumor, Sarcoid, Lymphadenopathy, Lymphoma
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Minneapolis, Minnesota • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 24, 2026, 7:04 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Registry and Fluid Banking of Pancreatic Cystic Lesions

NCT01769534
View directory record Official record
Conditions
Pancreatic Cysts
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Sep 24, 2026, 7:04 PM EDT
Not listed Not applicable Interventional

Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies

NCT04404101
View directory record Official record
Conditions
Pancreatic Cyst
Interventions
1). EUS-FNA plus MFB, 2). EUS-FNA Alone
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Irvine, California • Aurora, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 24, 2026, 7:04 PM EDT