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ClinicalTrials.gov public records Last synced Oct 9, 2026, 6:15 AM EDT

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Showing 97–120 of 449 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Enhance Treatment as Usual Clear all
Completed Not applicable Interventional Results available

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT

NCT04269772
View directory record Official record
Conditions
Bipolar Disorder
Interventions
CARE, Treatment As Usual
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Cranston, Rhode Island • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Terminated Phase 2 Interventional Results available

Telephone Support to Improve Adherence to Anti-HIV Medications

NCT00988442
View directory record Official record
Conditions
HIV Infections
Interventions
Enhanced nursing telephone support, Standard care
Behavioral
Lead sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Network
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
16
States / cities
Birmingham, Alabama • San Diego, California • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sensory Adapted Dental Environments to Enhance Oral Care for Children

NCT02430051
View directory record Official record
Conditions
Autism
Interventions
Sensory Adapted Dental Environment
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 12 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Pilot Study of Adjunctive Yoga for Bipolar Depression

NCT02402010
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Adjunctive Yoga, Enhanced Treatment as Usual
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning

NCT04889144
View directory record Official record
Conditions
Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Interventions
Communication Intervention, Best Practice, Questionnaire Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
New York, New York • Dallas, Texas • Seattle, Washington + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 2 Interventional

Field Trial of a Relapse Prevention Program for Adolescents Receiving Substance Use Treatment

NCT02125539
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Navigating my Journey program, Attention Control
Behavioral
Lead sponsor
Inflexxion, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2015 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Telephone-Based Counseling for Depression in Parkinson's Disease

NCT02505737
View directory record Official record
Conditions
Depression, Parkinson's Disease
Interventions
TH-CBT, Enhanced Usual Care
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
35 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 9, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional

Nurse-Led PTSD Treatment in Primary Care

NCT07430657
View directory record Official record
Conditions
Post Traumatic Stress Disorder PTSD
Interventions
NurseNET, Referral to PTSD Treatment
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Chicago, Illinois • Brookfield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression

NCT01572389
View directory record Official record
Conditions
Diabetes Mellitus, Depression
Interventions
Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 2 Interventional

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial

NCT06439420
View directory record Official record
Conditions
Primary Brain Tumor, Glioblastoma, Astrocytoma, Oligodendroglioma, Meningioma, Primary Central Nervous System (CNS) Lymphoma
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Not listed Phase 2 Interventional

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

NCT06434818
View directory record Official record
Conditions
Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder, Methamphetamine-dependence
Interventions
EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks, CBOT Sham
Combination Product
Lead sponsor
Evon Medics LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Oct 9, 2026, 6:15 AM EDT
Active, not recruiting Not applicable Interventional

Alcohol Screening and Preoperative Intervention Research Study - 2

NCT05783635
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Enhanced Usual Care (pre-operative), Preoperative Virtual Health Coaching, Usual surgical care (post-operative), Postoperative Virtual Health Coaching, On-Track (Post-operative)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 75 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Facilitating Aftercare for Alcohol Detox Patients

NCT00513708
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence
Interventions
Motivation Enhancement Therapy (MET), Peer-Twelve Step Facilitation (P-TSF)
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States

NCT04163341
View directory record Official record
Conditions
HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder, Substance Use Disorders
Interventions
Adapted Common Elements Treatment Approach
Behavioral
Lead sponsor
Michael J Mugavero, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 9, 2026, 6:15 AM EDT
Not yet recruiting Not applicable Interventional

NST-SPARK Open-Label Phase 1 STTR (IGNITE)

NCT07593456
View directory record Official record
Conditions
Schizophrenia / Schizoaffective Disorder
Interventions
NST-SPARK
Device
Lead sponsor
North Shore Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
2
States / cities
Glen Oaks, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional

Partnering With Antenatal Navigators to Transform Health in Pregnancy

NCT06941974
View directory record Official record
Conditions
Maternal Morbidity, Antenatal Health, Neonatal Morbidity, Retention in Care, Prenatal Care
Interventions
Patient Navigation Program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility, Acceptability, and Fidelity of Motivational Interviewing to Increase Maternal NICU Presence

NCT06488196
View directory record Official record
Conditions
Neonatal Intensive Care
Interventions
Motivational Interviewing, Treatment As Usual
Behavioral · Other
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 1 Interventional

Relapse Prevention for Suicidal Dually Diagnosed Youths

NCT00589641
View directory record Official record
Conditions
Suicide, Attempted, Suicide, Ideation, Depression, Substance Abuse
Interventions
CBT-RP (relapse prevention) + Enhanced TAU, Enhanced TAU Alone
Behavioral
Lead sponsor
Duke University
Other
Eligibility
13 Years to 19 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2014 · Synced Oct 9, 2026, 6:15 AM EDT
Terminated Not applicable Interventional Results available

Expanding Access to Home-Based Palliative Care

NCT03128060
View directory record Official record
Conditions
Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Interventions
Home-based palliative care, Enhanced usual care
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes

NCT03575468
View directory record Official record
Conditions
Smoking Cessation
Interventions
Enhanced E-cigarette Coaching, Quitline treatment as usual
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 9, 2026, 6:15 AM EDT
Active, not recruiting Phase 1 Interventional

A Study of Psilocybin for PTSD

NCT06407635
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Psilocybin, Trauma-focused psychotherapy, Standard psychological support
Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Active, not recruiting Not applicable Interventional

Prevention of Childhood Maltreatment in Families With Young Children

NCT04341376
View directory record Official record
Conditions
Child Maltreatment, Child Exposure to Intimate Partner Violence
Interventions
Enhanced First Connections
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Psychological Intervention Mobile App for Patients With AML

NCT03372291
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
Usual Care, Psychological intervention
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse

NCT03035877
View directory record Official record
Conditions
Antisocial Behavior
Interventions
Multisystemic Therapy-Emerging Adults, Enhanced Treatment as Usual
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
16 Years to 26 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
4
States / cities
Hamden, Connecticut • Hartford, Connecticut • New Haven, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 9, 2026, 6:15 AM EDT