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Showing 1–24 of 81 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Enhanced Behavioral Weight Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Exercise, and Technology for Weight Loss

NCT02731768
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard, Social support-enhanced, Fitbit Zip, Digital body weight scale
Behavioral · Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet Assisted Obesity Treatment Enhanced With Financial Incentives

NCT02688621
View directory record Official record
Conditions
Obesity
Interventions
Internet Only, Internet + Incentives
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Columbia, South Carolina • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Phase 2 Interventional

Innovative Approaches to Diet, Exercise and Activity

NCT01131871
View directory record Official record
Conditions
Body Weight
Interventions
Standard Behavioral Weight Loss Intervention, Enhanced Weight Loss Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 35 Years
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults

NCT06284681
View directory record Official record
Conditions
Obesity, Prehypertension, Hypertension, PreDiabetes, Type 2 Diabetes, Dyslipidemia
Interventions
Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach, Augment with enhanced medical management
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Recruiting Phase 2 Interventional

Uterine Preservation Via Lifestyle Transformation

NCT05903131
View directory record Official record
Conditions
Endometrial Hyperplasia, Grade 1 Endometrial Cancer
Interventions
Telemedicine behavioral weight intervention, Progestin, Enhanced usual care, Levonorgestrel-releasing IUD.
Behavioral · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
3
States / cities
St Louis, Missouri • Albuquerque, New Mexico • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

Collaborative Multi-level Obesity Intervention Engaging Communities Trial

NCT06835686
View directory record Official record
Conditions
Obesity
Interventions
Health Literacy and Culturally Tailored Materials, Community-Engaged Health Coaching and Navigation, Self-Monitoring and Remote Patient Monitoring of weight and physical activity, Community Asset Mapping (CAM), Primary Care Provider Training, Obesity Toolkit for Primary Care Providers
Behavioral · Other
Lead sponsor
Tulane University
Other
Eligibility
18 Years to 75 Years
Enrollment
522 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
18
States / cities
Avondale, Louisiana • Bastrop, Louisiana • Baton Rouge, Louisiana + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Child Care Staff Weight Management Program

NCT05656807
View directory record Official record
Conditions
Obesity
Interventions
Go NAPSACC Enhanced, Go NAPSACC
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
2 Years and older
Enrollment
924 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Withdrawn Not applicable Interventional

Families, Responsibility, Education, Support, and Health for Executive Function

NCT05165511
View directory record Official record
Conditions
Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
Interventions
PBT-EF
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sharing Digital Self-Monitoring Data With Others to Enhance Long-Term Weight Loss

NCT05180448
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Coach Share On, Group Share On, Friend/Family Share On, Coach Share Off, Group Share Off, Friend/Family Share Off, Behavioral Weight Loss Treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

The Healthy Eating and Active Living to Reverse Diabetes Pilot Study

NCT07316569
View directory record Official record
Conditions
Diabete Type 2, Diabetes, Overweight , Obesity
Interventions
Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 4, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer

NCT05780814
View directory record Official record
Conditions
Breast Cancer, Insomnia, Weight Gain
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBT-I), Sleep Education Control (EDU)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa

NCT05799872
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Positive Affect Treatment for Anorexia Nervosa (PAT-AN):, Psychoeducational and Behavioral Therapy (PBT)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Not listed Not applicable Interventional

An ACT-enhanced Weight Management and Fitness Program for Navy Personnel

NCT03029507
View directory record Official record
Conditions
Obesity, Overweight
Interventions
ACT Enhanced ShipShape, Standard ShipShape (SS)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 69 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Innovative Technology To Improve Patient Adherence To Weight Loss Recommendations

NCT01222858
View directory record Official record
Conditions
Obesity
Interventions
Diet and Activity Education, Self-monitoring with Feedback
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 7, 2014 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Shape Up Rhode Island Campaign Study 5

NCT00948415
View directory record Official record
Conditions
Obesity
Interventions
Evaluation of the Shape Up RI Campaign
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 7, 2014 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

Lifestyle Intervention for Young Adults With Serious Mental Illness

NCT02815813
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder, Overweight, Obesity
Interventions
PeerFIT, BEAT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
New Britain, Connecticut • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

The GEM (Goals for Eating and Moving) Study

NCT03006328
View directory record Official record
Conditions
Weight Gain, Obesity
Interventions
GEM, Enhanced Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 69 Years
Enrollment
489 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 2, 2026, 10:12 AM EDT
Enrolling by invitation Not applicable Interventional

To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years

NCT07387393
View directory record Official record
Conditions
Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus (T2DM), Overweight (BMI > 25), Weight Loss Trial
Interventions
PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Fayetteville, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Peer-enhanced Intervention to Support Teen Weight Loss

NCT00285558
View directory record Official record
Conditions
Obesity
Interventions
CBT with peer-enhanced activities, CBT with supervised aerobic exercise
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
13 Years to 16 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Veterans Walk for Health Study

NCT00123435
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Hyperlipidemia, Hypertension, Obesity
Interventions
Nutritional counseling, Walking program, Simple pedometer, Enhanced pedometer
Behavioral · Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 20, 2015 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Diabetes Prevention for Mexican Americans

NCT03208010
View directory record Official record
Conditions
Prediabetic State, Overweight and Obesity
Interventions
Diabetes Prevention Intervention, Enhanced Usual Care
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
25 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rio Grande City, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families

NCT05944549
View directory record Official record
Conditions
Weight Loss
Interventions
Financial coaching using TrustPlus, Brighter Bites, Noom
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program

NCT05981508
View directory record Official record
Conditions
Body Weight, Body Weight Changes, Obesity, Overweight and Obesity, Overweight, Behavior, Eating, Physical Inactivity, Chronic Disease, Weight Loss, Weight Reduction
Interventions
Together, Eating and Activity, Matter Plus (TEAM+) Online, Together, Eating and Activity, Matter Plus (TEAM+) In-Person
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Sep 2, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Motivational Interviewing for Weight Loss With Young Adults

NCT01899625
View directory record Official record
Conditions
Obesity
Interventions
Brief Behavioral Weight Loss (BWL), Motivation Enhanced BWL
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2016 · Synced Sep 2, 2026, 10:12 AM EDT