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ClinicalTrials.gov public records Last synced Nov 14, 2026, 4:24 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 51 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Enhanced Consent Procedure Clear all

Conditions: End Stage Renal Disease
Interventions: SPIRIT-Dementia, Usual Care; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 4
States / cities: Atlanta, Georgia • Decatur, Georgia

Conditions: Human Immunodeficiency Virus
Interventions: Staff-delivered intervention sessions, Demographic Questionnaire, Questionnaires; Behavioral · Other
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 13 Years to 24 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Emergency Department, Health, Subjective, Health Care Utilization
Interventions: PATH Intervention; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Diabetes Mellitus, Type 1
Interventions: Planet T1D; Behavioral
Lead sponsor: 3-C Institute for Social Development; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Pain, Drug Overdose, Opioid Use Disorders
Interventions: Motivational intervention, Psycho-educational control, Long-term opioid therapy informed consent; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 299 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Schizophrenia
Interventions: DVD Consent, Routine Control; Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 40 Years and older
Enrollment: 382 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Opioid Use Disorder
Interventions: Youth Opioid Recovery Support (YORS); Behavioral
Lead sponsor: Potomac Health Foundations; Other
Eligibility: 13 Years to 21 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Delirium, Confusion, Mental Status Change, Back Pain, Hip Pain Chronic, Chest Pain, Asthma, COPD, Cellulitis, Soft Tissue Infections, Cough, Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism, Dyspnea, Electrolyte Metabolism Abnormal, Fever, Failure to Thrive, Weakness, Protein-Calorie Malnutrition, Headache, Neck Pain, Hypoxia, Pneumonia, Sepsis, Syncope, Vomiting, Diarrhea, Leg Pain, Abdominal Pain
Interventions: Diagnostic Uncertainty Educational Curriculum, Diagnostic Timeout, Patient Diagnostic (Dx) Questionnaire, Enhancements to Epic-integrated Quality & Safety Dashboard; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depression, Dysthymia
Interventions: ADAPt-C intervention; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 472 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation, POLE Gene Mutation, APC Gene Mutation, ATM Gene Mutation, MLH1 Gene Mutation, BARD1 Gene Mutation, MSH2 Gene Mutation, BRIP1 Gene Mutation, MSH6 Gene Mutation, CHEK2 Gene Mutation, PMS2 Gene Mutation, PALB2 Gene Mutation, EPCAM Gene Mutation, RAD51C Gene Mutation, BMPR1A Gene Mutation, RAD51D Gene Mutation, SMAD4, PTEN Gene Mutation, GREM1
Interventions: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: PreDiabetes, Metabolic Syndrome, Protection Against
Interventions: DPPFit; Behavioral
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Sinus Pause, Sinus Sick Syndrome, Heart Block, Arrhythmias, Cardiac
Interventions: Cardiac Imaging by TTE or CTA; Diagnostic Test
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 18 Years to 89 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Telemedicine
Interventions: Enhanced Usual Care, Super Supporter Support; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 1,111 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: Charlotte, North Carolina • Winston-Salem, North Carolina

Conditions: Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
Interventions: Components of Genetic Counseling, APOL1 genetic testing, EHR integration; Behavioral · Diagnostic Test · Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Chicago, Illinois

Conditions: Metastatic Breast Cancer
Interventions: Palliative Care Intervention, "TARGET-PC", Enhanced Usual Care; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 3
States / cities: Boston, Massachusetts • Durham, North Carolina • Philadelphia, Pennsylvania

Conditions: High Risk Prostate Carcinoma, Prostate Cancer
Interventions: Abiraterone acetate, Prednisone, Hyperpolarized [1-13C] pyruvate (HP 13C), Magnetic Resonance Imaging (MRI), Non-investigational radical prostatectomy (RP), Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) PET/Computerized tomography (CT); Drug · Procedure
Lead sponsor: Ivan de Kouchkovsky, MD; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2031
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Drug Usage, Drug Abuse, Drug Dependence
Interventions: Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 589 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Systemic Sclerosis
Interventions: RENEW; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Surgery, Cholecystectomy, Laparoscopic, Prostatectomy, Arthroplasty, Replacement, Hip, Endarterectomy, Carotid
Interventions: Enhanced surgical iMedConsent process (with "repeat back"), standard surgical iMedConsent process; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 575 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 7
States / cities: Denver, Colorado • Tampa, Florida • Decatur, Georgia + 4 more

Conditions: Stress Urinary Incontinence, Urge Incontinence, Pelvic Organ Prolapse
Interventions: audiovisual decision aid; Other
Lead sponsor: Loyola University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Pediatric Crohn's Disease
Interventions: Enhanced Pre-Consent Discussion, Standard Pre-consent Discussion; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 241 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Intimate Partner Violence (IPV)
Interventions: IDEA3 Sexual Assault Resistance Intervention, Consent workshop; Behavioral
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 17 Years to 26 Years
Enrollment: 289 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 3
States / cities: Orlando, Florida • College Park, Maryland • Ann Arbor, Michigan

Conditions: Suicide, Suicide Prevention, Suicide and Self-harm
Interventions: Caring Contacts; Behavioral
Lead sponsor: St. Luke's Health System, Boise, Idaho; Other
Eligibility: 12 Years and older
Enrollment: 854 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Boise, Idaho

Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions: Educational Cancer Intervention, ICF Text Version 1, ICF Text Version 2, ICF Video Version 1, ICF Video Version 2, ICF Video Version 3, ICF Video Version 4, Survey Administration; Behavioral · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Jacksonville, Florida

Search by objective public record fields.

SPIRIT for Persons With Dementia and Complex Multimorbidity

Medication Adherence in Human Immunodeficiency Virus (HIV)

Practical Alternative to Hospitalization

Mobile Technology & Online Tools to Track Adherence in Chronic Illness Patients

Primary Care Intervention to Reduce Prescription Opioid Overdoses

Comparison of Video Consent Versus Routine Consent for Participation in Research Studies

Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD

Improving Safety of Diagnosis and Therapy in the Inpatient Setting

Treating Depression Among Low-Income Patients With Cancer

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting

Multimodality Location Prediction Accuracy of Leadless Pacemaker Positioning

Super-Supporters - Virtual Care Technology Navigators

APOL1 Genetic Testing Program for Living Donors

Targeted Palliative Care Intervention for Patients With Metastatic Breast Cancer

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use

Self-Guided Resilience-Building Energy Management to Enhance Well-being (RENEW) Intervention for People With Systemic Sclerosis (SSc)

Benefits of 'Repeat Back' Protocols Within A Computer-Based Informed Consent Program

Enhanced Consent and Preparedness for Surgery Trial

Trial of Enhanced Pre-Consent Discussion

Can the IDEA3 Intervention Prevent Intimate Partner Violence?: A Substudy to the IDEA3 Randomized Controlled Trial

Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial

Community Enhanced Virtual Informed Consent