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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Enhanced Implementation Approach Clear all
Completed Not applicable Interventional

Implementation Science Approach to Enhancing Depression Treatment in Collaborative Depression Care Settings ( DepCare )

NCT05085886
View directory record Official record
Conditions
Depressive Symptoms
Interventions
DepCare, Enhanced Usual Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
605 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Methods for Implementation of a Comfort Care Order Set

NCT02383173
View directory record Official record
Conditions
Terminal Conditions, End of Life
Interventions
Basic Implementation Approach, Enhanced Implementation Approach
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

NCT05319535
View directory record Official record
Conditions
Cognitive Function, Functional Status
Interventions
Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Implementing Group Physical Therapy (PT) for Veterans With Knee Osteoarthritis (Group PT): Function QUERI 2.0

NCT05282927
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP (enREP)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Recruiting Not applicable Interventional

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

NCT05929703
View directory record Official record
Conditions
Delirium, Neurocognitive Disorders, Mild Cognitive Impairment, Alzheimer Disease, Aging, Family Support, Family Members, Caregiver Burden, Implementation Science, Patient Satisfaction
Interventions
HELP, FAM-HELP
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
70 Years and older
Enrollment
1,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Orange, California • Portland, Maine • Ann Arbor, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

West Philadelphia Controls Asthma

NCT03514485
View directory record Official record
Conditions
Childhood Asthma, Community Health Workers
Interventions
Yes We Can Children's Asthma Program, School-Based Asthma Therapy, Open Airways for School Plus
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 13 Years
Enrollment
626 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Transdiagnostic CBT for Comorbid Alcohol Use and Anxiety Disorders

NCT03230006
View directory record Official record
Conditions
Alcohol Use Disorder, Anxiety Disorders
Interventions
Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, Take Control
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Not listed Not applicable Interventional

Peer Wellness Enhancement For Patients With Serious Mental Illness and High Medical Costs

NCT03673852
View directory record Official record
Conditions
Chronic Medical Condition
Interventions
WE Harambee, Behavioral Health Home Enrollment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Sep 4, 2026, 4:32 AM EDT
Enrolling by invitation Not applicable Interventional

Collaborative Approach to Reach Everyone With Familial Hypercholesterolemia (CARE-FH)

NCT05284513
View directory record Official record
Conditions
Familial Hypercholesterolemia
Interventions
FH diagnosis program, Implementation strategy package: Develop and implement tools for quality monitoring, Implementation strategy package: Develop educational materials, Implementation strategy package: Conduct educational outreach visits, Implementation strategy package: Intervene with clinicians and patients to enhance, Behavioral (e.g., Psychotherapy, Lifestyle Counseling) Implementation strategy package: Identify and prepare champions Clinical lipid champions, Implementation strategy package: Audit and provide feedback, Implementation strategy package: Stage implementation scale up
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
26 Years and older
Enrollment
532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Multiple Locations, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Substance Use Among Youth

NCT04752189
View directory record Official record
Conditions
Substance Abuse
Interventions
Enhanced Replicating Effective Programs (Enhanced REP), Standard implementation
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
14 Years to 99 Years
Enrollment
825 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Sep 4, 2026, 4:32 AM EDT
Enrolling by invitation Not applicable Interventional

To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years

NCT07387393
View directory record Official record
Conditions
Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus (T2DM), Overweight (BMI > 25), Weight Loss Trial
Interventions
PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Fayetteville, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Tribally Engaged Approaches to Lung Screening (TEALS)

NCT04948060
View directory record Official record
Conditions
Lung Cancer
Interventions
Enhanced lung cancer screening services
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
50 Years to 80 Years
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Suicide Safety Planning Group Treatment: "Project Life Force"

NCT02525575
View directory record Official record
Conditions
Suicide
Interventions
Project Life Force Group Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maine Implementation Study - Phase III

NCT02229305
View directory record Official record
Conditions
Anxiety, Trauma, Depression, Problem Behavior
Interventions
Usual Care Treatment, Modular Approach to Therapy for Children
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
6 Years to 15 Years
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2014 · Synced Sep 4, 2026, 4:32 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Getting to Zero Among HHI MSM in the American South

NCT05075967
View directory record Official record
Conditions
HIV Infections
Interventions
Health Access Coalitions, Social Media, Peer Support, Promoting Human Autonomy Support & Empathy (PHASE)
Behavioral
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
15 Years and older · Male only
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Recruiting Not applicable Interventional

Primary Care Evidence-based Approach for Improving Lifelong Health

NCT06526312
View directory record Official record
Conditions
Clinical Trial
Interventions
SMS/Text (CAMPI), Fidelity Monitoring (Lyssn and COACH), Family Check-Up 4 Health (FCU4Health)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
2 Years to 99 Years
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Recruiting Not applicable Interventional

Peer-Delivered Behavioral Activation in a CCBHC

NCT07219394
View directory record Official record
Conditions
Major Depressive Disorder, Substance Use Disorders
Interventions
Peer Activate, Peer-delivered non-specific services
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Evaluation of the Walk With Ease Program for Fall Prevention

NCT05693025
View directory record Official record
Conditions
Exercise, Frailty, Arthritis, Accidental Falls
Interventions
Group Exercise, Behavioral Training
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Sep 4, 2026, 4:32 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Delivery of Parenting Support Within a Peer Recovery Support Service Model

NCT07743359
View directory record Official record
Conditions
Substance Use Disorders (SUDs)
Interventions
Relational Health Enhanced Parenting Support (RHEP) implementation bundle, First Steps Together
Other · Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older
Enrollment
288 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Recruiting Not applicable Interventional

Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid)

NCT06494384
View directory record Official record
Conditions
Depression
Interventions
Problem Solving Treatment as usual (PST as usual), Problem Solving Treatment Aid (PST-Aid)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

Positive Minds Strong Bodies Implementation

NCT04545593
View directory record Official record
Conditions
Depression, Anxiety, Physical Disability
Interventions
Positive Minds Strong Bodies Enhanced, Enhanced Usual Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older
Enrollment
427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motiv82Change: an HIV Prevention Study for Young Latino Men

NCT00877695
View directory record Official record
Conditions
HIV Infections
Interventions
Entre Culturas: Navigating Culture, Identity, and HIV Risk
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2013 · Synced Sep 4, 2026, 4:32 AM EDT
Completed Not applicable Interventional Results available

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

NCT04523779
View directory record Official record
Conditions
Anxiety
Interventions
Brief Cognitive Behavioral Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
New Orleans, Louisiana • Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 4, 2026, 4:32 AM EDT
Recruiting Not applicable Interventional

Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior

NCT05390918
View directory record Official record
Conditions
Insomnia, Suicidal Ideation, Suicide, Attempted
Interventions
TAILOR, Enhanced Usual Care
Behavioral · Other
Lead sponsor
Jeff Bridge
Other
Eligibility
11 Years to 18 Years
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 4, 2026, 4:32 AM EDT