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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Enhanced Psychotherapy Clear all
Completed Not applicable Interventional

Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

NCT00902798
View directory record Official record
Conditions
Autistic Disorder, Autism Spectrum Disorder, Asperger's Syndrome, Pervasive Developmental Disorder
Interventions
Cognitive Enhancement Therapy, Enriched Supportive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 45 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2020 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Phase 2 Interventional

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial

NCT06439420
View directory record Official record
Conditions
Primary Brain Tumor, Glioblastoma, Astrocytoma, Oligodendroglioma, Meningioma, Primary Central Nervous System (CNS) Lymphoma
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 1, 2026, 6:07 PM EDT
Active, not recruiting Not applicable Interventional

Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain

NCT06044649
View directory record Official record
Conditions
Chronic Pain, Neck Pain, Back Pain
Interventions
Cognitive Behavioral Therapy, Acceptance and Commitment Therapy, Emotional Awareness and Expression Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

A Novel fNIRS Neurofeedback Intervention for Enhancement of Working Memory in Attention Deficit Hyperactivity Disorder (ADHD)

NCT04002167
View directory record Official record
Conditions
ADHD
Interventions
Neurofeedback, Cognitive training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 11 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mindfulness-based Stress Reduction for Urban Youth

NCT00661271
View directory record Official record
Conditions
Stress, Psychological
Interventions
Mindfulness-based stress reduction (MBSR), Healthy topics
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
14 Years to 22 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Telephone Based Cognitive Behavioral Therapy for HIV Related Depression

NCT01055158
View directory record Official record
Conditions
Depression, HIV Infections
Interventions
Telephone-based CBT, Enhanced Usual Care
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Effects of Mindfulness Training on Chronic Inflammation in HIV-Infected Adults

NCT02626949
View directory record Official record
Conditions
HIV
Interventions
MBSR Course, HEP Course
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
45 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Engaging Latino Families in Eating Disorders Treatment

NCT01470508
View directory record Official record
Conditions
Bulimia Nervosa, Binge Eating Disorder, Eating Disorder Not Otherwise Specified
Interventions
Cognitive Behavioral Therapy, Cognitive Behavioral Therapy with Family Enhancement
Behavioral
Lead sponsor
Mae Lynn Reyes-Rodriguez, PhD
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

NCT03954210
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Behavioral Medicine Intervention With Depressed Patients in a Community Health Center Setting

NCT01330420
View directory record Official record
Conditions
Depression
Interventions
Relaxation Response Resiliency Program for Depression
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charlestown, Massachusetts • Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

CBT Enhanced With Social Cognitive Training

NCT03954392
View directory record Official record
Conditions
Depression
Interventions
Cognitive behavior therapy with social cognitive training (CBT+SCT), CBT-only
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
12 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Sep 1, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder

NCT04625959
View directory record Official record
Conditions
Bulimia Nervosa, Bulimia; Atypical, Binge-Eating Disorder, Binge-Eating and Purging Type Anorexia Nervosa, Binge Eating
Interventions
Behavioral Therapy for Eating Disorders, MABT: Mindful Awareness, MABT: Values, MABT: Emotion Modulation, MABT: Distress Tolerance
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 24, 2023 · Synced Sep 1, 2026, 6:07 PM EDT
Active, not recruiting Phase 2 Interventional

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

NCT05737693
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Ketamine, Midazolam
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 70 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Reducing Fetal Exposure to Maternal Depression to Improve Infant Risk Mechanisms

NCT03011801
View directory record Official record
Conditions
Depression
Interventions
Interpersonal Therapy, Enhanced usual care
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older · Female only
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Denver, Colorado • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts

NCT04225624
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Attachment Based Family Therapy for Suicidal Adolescents

NCT01537419
View directory record Official record
Conditions
Suicide, Depression, Family Relationships
Interventions
Attachment-Based Family Therapy, Family-Enhanced Non-directive Supportive Therapy
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
12 Years to 18 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Sep 1, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

Post Admission Cognitive Therapy (PACT) for the Inpatient Treatment of Military Personnel With Suicidal Behaviors

NCT01359761
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation Active
Interventions
Post Admission Cognitive Therapy (PACT)
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
4
States / cities
Bethesda, Maryland • Durham, North Carolina • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional

iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes

NCT02980627
View directory record Official record
Conditions
Type 1 Diabetes Mellitus, Eating Disorders
Interventions
Therapy with Mobile App Enhancement
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Sep 1, 2026, 6:07 PM EDT
Not yet recruiting Not applicable Interventional

Prediction and Prevention of Postoperative Mortality and Morbidity

NCT06042413
View directory record Official record
Conditions
Dementia, Postoperative Delirium (POD), Postoperative Neurocognitive Disorder, Major Adverse Cardiac and Cerebrovascular Events, Perioperative Complications, Postoperative Cognitive Decline
Interventions
Personalized CPC Prehabilitation, Cognitive Training, Meditation, Daily Exercise, Enhanced Social Support, Proactive Bundle Interventions, Pre-operative Standard of Care, Intra-operative Standard of Care
Other · Behavioral · Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Phase 3 Interventional

Motivational Incentives for Enhanced Drug Abuse Recovery: Methadone Clinics. - 1

NCT00033020
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
7
States / cities
Bakersfield, California • Washington D.C., District of Columbia • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

NCT04523779
View directory record Official record
Conditions
Anxiety
Interventions
Brief Cognitive Behavioral Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
New Orleans, Louisiana • Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Enrolling by invitation Not applicable Interventional

Resilience and Brain Health of Older Adults (MEDEX-2)

NCT05124132
View directory record Official record
Conditions
Age-related Cognitive Decline
Interventions
Mindfulness-Based Stress Reduction, Exercise, Mindfulness-Based Stress Reduction + Exercise, Health Education
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years and older
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 1, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Integrated vs Sequential Treatment for PTSD and Addiction

NCT01211106
View directory record Official record
Conditions
PTSD, Substance Addiction
Interventions
Prolonged Exposure, Motivational Enhancement Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Minneapolis, Minnesota • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Sep 1, 2026, 6:07 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

ACT for Individuals With MNCD and Their Care Partners

NCT07239609
View directory record Official record
Conditions
Depression in Adults, Anxiety Disorder Generalized, Grief
Interventions
Acceptance Commitment Therapy
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 1, 2026, 6:07 PM EDT