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ClinicalTrials.gov public records Last synced Oct 7, 2026, 10:48 AM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Enhanced Treatment as Usual (ETAU) Clear all
Completed Not applicable Interventional Results available

A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail

NCT02334215
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Methadone, Patient Navigation, Enhanced Treatment as Usual (ETAU)
Drug · Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional

Suicide Prevention Intervention for Schizophrenia-Spectrum Disorders

NCT04221269
View directory record Official record
Conditions
Schizophrenia, Suicide
Interventions
Enhanced Treatment as Usual, Coping Long-term with Active Suicide Program for Schizophrenia
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 7, 2026, 10:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)

NCT06501781
View directory record Official record
Conditions
HIV Infections, Substance Use
Interventions
Peer Activate-LAI, Standard of Care HIV treatment or prevention with LAI-PrEP/ART
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional

REACH-Es: Adapting a Digital Health Tool to Improve Diabetes Medication Adherence Among Latino Adults

NCT06000813
View directory record Official record
Conditions
Type 2 Diabetes (Adult Onset), Medication Adherence
Interventions
REACH-Es, ETAU
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Phase 4 Interventional Results available

Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry

NCT01999946
View directory record Official record
Conditions
Heroin Dependence, Opioid-Related Disorders
Interventions
Extended-Release Naltrexone
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PREPP: Preventing Postpartum Depression

NCT03283254
View directory record Official record
Conditions
Postpartum Depression (PPD)
Interventions
Practical Resources for Effective Postpartum Parenting (PREPP), Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Phase 2 Interventional

Girls In Recovery From Life Stress (GIRLS) Study

NCT00751946
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Trauma Adaptive Recovery Group Education and Therapy, Enhanced Treatment As Usual
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
13 Years to 17 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
7
States / cities
East Hartford, Connecticut • Farmington, Connecticut • Hartford, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2010 · Synced Oct 7, 2026, 10:48 AM EDT
Terminated Not applicable Interventional

Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals

NCT06654414
View directory record Official record
Conditions
Smoking Cessation, Depression, Anxiety, Nicotine Dependence, Gender Minority Stress
Interventions
PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Active, not recruiting Not applicable Interventional

Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women With HIV in South Africa: Part 2

NCT06182241
View directory record Official record
Conditions
Cervical Cancer, Hiv
Interventions
Retention in cervical cancer care intervention
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Chronic Pain in Integrated Primary Care

NCT04978961
View directory record Official record
Conditions
Chronic Pain
Interventions
Focused Acceptance & Commitment Therapy (FACT), Enhanced Treatment as Usual (ETAU)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 99 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Phase 2 Interventional Results available

Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma

NCT00384813
View directory record Official record
Conditions
Asthma
Interventions
Project ASPIRE Home-Based Family Intervention, Project ASPIRE Enhanced Treatment As Usual
Behavioral
Lead sponsor
Emory University
Other
Eligibility
8 Years to 13 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Atlanta, Georgia • Smyrna, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2014 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional

Effectiveness RCT of Customized Adherence Enhancement

NCT04622150
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Customized Adherence Enhancement (CAE), Enhanced Treatment as Usual (eTAU)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 89 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Cleveland, Ohio • Lorain, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Women's Initiative Supporting Health Increasing Healthcare Access

NCT02964845
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
WISH with CHW and referral to HFM, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Results available

Skills Based Counseling for Adherence and Depression in HIV+ Methadone Patients - 1

NCT00218634
View directory record Official record
Conditions
Adherence, Depression, Heroin Dependence, Methadone, Motivational Interviewing, Substance-Related Disorders
Interventions
CBT-AD, ETAU
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Examining Community-based Effectiveness of a Substance Use and HIV Risk Reduction Intervention for Young Men of Color

NCT03488914
View directory record Official record
Conditions
Substance Use, Sexual Risk
Interventions
YMHP Intervention, Enhanced Treatment as Usual
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
2
States / cities
Brooklyn, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized, Augmented Cognitive Training (PACT) for Service Members and Veterans with a History of TBI

NCT04560946
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Personalized Augmented Cognitive Training (PACT), Enhanced Treatment As Usual
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 55 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 7, 2026, 10:48 AM EDT
Suspended Not applicable Interventional

From Hardship to Hope: A Peer-led Intervention to Reduce Financial Hardship and Suicide Risk

NCT04840134
View directory record Official record
Conditions
Suicide, Suicide Ideation, Suicidal Behavior, Hope, Financial Stress
Interventions
From Hardship to Hope: A Peer-led intervention to reduce financial hardship and suicide risk, Enhanced Treatment as Usual (eTAU)
Behavioral · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Results available

Integrated Treatment for Smoking Cessation & Anxiety in People With HIV

NCT01393301
View directory record Official record
Conditions
Nicotine Dependence, Symptoms of Anxiety, HIV
Interventions
Integrated cognitive-behavioral therapy for smoking cessation and anxiety, Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Results available

Improving Adherence in Adolescents and Young Adults With Bipolar Disorder

NCT04348604
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Customized Adherence Enhancement for Adolescents and Young Adults (CAE-AYA), Enhanced Treatment as Usual (ETAU)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
14 Years to 21 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional

Researching the Effectiveness of Acceptance-Based Coping During Hospitalization

NCT02336581
View directory record Official record
Conditions
Psychosis, Schizophrenia
Interventions
Acceptance and Commitment Therapy (ACT), Enhanced Treatment as Usual (eTAU)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 20, 2017 · Synced Oct 7, 2026, 10:48 AM EDT
Recruiting Not applicable Interventional

RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry

NCT07136363
View directory record Official record
Conditions
HIV, Stimulant Use Disorder, Justice Involved Populations, HIV Prevention
Interventions
DynamiCare, Patient Navigation (PN)
Device · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional

Early Adolescent Skills for Emotions Tanzania Pilot

NCT04082026
View directory record Official record
Conditions
Mental Health Wellness 1
Interventions
Early Adolescent Skills for Emotions EASE)
Behavioral
Lead sponsor
International Rescue Committee
Other
Eligibility
10 Years to 14 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 7, 2026, 10:48 AM EDT
Recruiting Not applicable Interventional

Towards Testing the Effectiveness of Recovery Community Centers (RCCs)

NCT07010978
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Recovery Community Center Participation, Enhance Treatment as Usual
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 7, 2026, 10:48 AM EDT
Completed Not applicable Interventional Results available

CAE for Poorly Adherent Individuals With Schizophrenia

NCT06061952
View directory record Official record
Conditions
Schizophrenia
Interventions
Customized Adherence Enhancement for Schizophrenia (CAE-S), Enhanced Treatment as Usual (eTAU)
Behavioral · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 7, 2026, 10:48 AM EDT