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ClinicalTrials.gov public records Last synced Oct 5, 2026, 6:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 98 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Enhanced treatment-as-usual (TAU) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Jail-Based Use of Smoking Cessation Treatment Study

NCT03799315
View directory record Official record
Conditions
Tobacco Use
Interventions
Nicotine Replacement Therapy, Counseling
Drug · Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2020 · Synced Oct 5, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

NCT05973838
View directory record Official record
Conditions
Polysubstance Addiction, Opioid Medication Assisted Treatment, Treatment Adherence, Retention in Care, Substance-Related Disorders
Interventions
Peer-Delivered Behavioral Activation ("Peer Activate")
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • College Park, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 5, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional

M2VA Pain Care Pathway

NCT06526143
View directory record Official record
Conditions
Pain, Substance Use, Opioid Misuse, Quality of Life
Interventions
M2VA Pain Care Pathway (M2VAPCP), Implementation Facilitation
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional

Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services

NCT06769282
View directory record Official record
Conditions
Aggression Childhood, Teen Dating Violence
Interventions
Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Recruiting Phase 3 Interventional

Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment

NCT06032559
View directory record Official record
Conditions
Opioid Use, Pain
Interventions
MORE, SMP, TAU
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Brunswick, New Jersey • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Active, not recruiting Not applicable Interventional

Using the Ending Self-Stigma Intervention to Reduce Internalized Stigma Among People Living With HIV Who Use Substances

NCT05704764
View directory record Official record
Conditions
HIV, Stigma, Social, Substance Use
Interventions
Ending Self Stigma for Persons living with HIV and Use Substances
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Newhall, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chicago Community Health Study

NCT04460417
View directory record Official record
Conditions
Smoking
Interventions
Enhanced Care, TAU
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

Mindfulness Oriented Recovery Enhancement for Chronic Pain and Opioid Relapse

NCT04491968
View directory record Official record
Conditions
Opioid Use, Chronic Pain
Interventions
Mindfulness Oriented Recovery Enhancement, Methadone Treatment as Usual
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Not listed Phase 2 Interventional

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

NCT06434818
View directory record Official record
Conditions
Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder, Methamphetamine-dependence
Interventions
EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks, CBOT Sham
Combination Product
Lead sponsor
Evon Medics LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes

NCT03575468
View directory record Official record
Conditions
Smoking Cessation
Interventions
Enhanced E-cigarette Coaching, Quitline treatment as usual
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional

PATH For Triples Study: Medication and Lifestyle Adherence for HIV+ Patients

NCT02185144
View directory record Official record
Conditions
HIV
Interventions
PATH For Triples, Treatment as Usual
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

Brief Interventions for Short-Term Suicide Risk Reduction in Military Populations

NCT02042131
View directory record Official record
Conditions
Suicide, Suicidal Ideation
Interventions
Treatment As Usual (TAU), Standard Crisis Response Plan (S-CRP), Enhanced Crisis Response Plan (E-CRP)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 11, 2017 · Synced Oct 5, 2026, 6:19 PM EDT
Active, not recruiting Not applicable Interventional

Virtual Reality Cognitive-Affective Training for Opioid Use Disorder- A Phase 2 RCT

NCT06021431
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
MORE-VR, Treatment as Usual
Device · Other
Lead sponsor
BehaVR LLC
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
La Jolla, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

A Brief Community Linkage Intervention for Dually Diagnosed Individuals

NCT00137267
View directory record Official record
Conditions
Schizophrenia, Psychotic Disorders, Substance-Related Disorders, Bipolar Disorder
Interventions
Time limited case management, Health Education
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Bedford, Massachusetts • East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 15, 2015 · Synced Oct 5, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional

Adjunctive Motivational Alcohol Intervention to Prevent IPV

NCT05287711
View directory record Official record
Conditions
Alcohol Use and Intimate Partner Violence
Interventions
Motivational Enhancement Therapy, Alcohol Education Control, Treatment as Usual, Strength at Home
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional

Social Cognition and Interaction Training for Autism

NCT02382172
View directory record Official record
Conditions
Autism, Social Behavior
Interventions
Social Cognition and Interaction Training for Autism (SCIT-A), Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
10 Years to 69 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Carrboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Disparities in Behavioral Health Treatment for Children in Primary Care

NCT04082234
View directory record Official record
Conditions
ADHD
Interventions
Partnering to Achieve School Success (PASS), Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 11 Years
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users

NCT01614106
View directory record Official record
Conditions
HIV, AIDS, Substance Abuse
Interventions
Retention Clinic
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
2
States / cities
Miami, Florida • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 12, 2022 · Synced Oct 5, 2026, 6:19 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Palliative Care Needs of Children With Rare Diseases and Their Families

NCT06938542
View directory record Official record
Conditions
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome, Early Infantile Epileptic Encephalopathy, FOXG1 Syndrome, KBG Syndrome, Noonan Syndrome, Severe Hemophilia A, Short Bowel Syndrome, Beta-Propeller Protein-Associated Neurodegeneration, Brain Injury of Prematurity With Periventricular Leukomalacia, Chromosome 17p13.3 Microdeletion Syndrome, Chromosome 1q43-1q44 Deletion, Cockayne Syndrome, Congenital Diaphragmatic Hernia, End-Stage Renal Disease With Cloacal Anomaly, Mitochondrial Depletion Disorder, Severe Factor VII Deficiency
Interventions
Family Centered pediatric palliative care for family caregivers of children with rare diseases.
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
12 Months to 99 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Treatment to Enhance Risk Perception in Sleep Apnea

NCT02314858
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Brief Personalized Video (BPV), Non-Personalized Video (NPV), Treatment as Usual (TAU)
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
21 Years to 80 Years
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco

NCT04737772
View directory record Official record
Conditions
Smoking Cessation, Marijuana Use
Interventions
Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
21 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT

NCT04269772
View directory record Official record
Conditions
Bipolar Disorder
Interventions
CARE, Treatment As Usual
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Cranston, Rhode Island • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Phase 1Phase 2 Interventional

Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders

NCT00600470
View directory record Official record
Conditions
Attention Deficit and Disruptive Behavior Disorders
Interventions
Doctor-office collaborative care (DOCC) management, Treatment as usual (TAU)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 12 Years
Enrollment
858 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Oct 5, 2026, 6:19 PM EDT
Completed Not applicable Interventional

Treatment of Opioid Use: Medication Adherence Therapy

NCT03567356
View directory record Official record
Conditions
Opioid Dependence, Opioid-Related Disorders
Interventions
MAT-PLUS "Helping Hands"
Other
Lead sponsor
Potomac Health Foundations
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 5, 2026, 6:19 PM EDT