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Showing 1–24 of 238 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Epidural Analgesia Clear all
Terminated Not applicable Interventional Results available

Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine

NCT00616577
View directory record Official record
Conditions
Inguinal Herniorrhaphy, Orchiopexy
Interventions
Ropivacaine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
Up to 2 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Sep 20, 2026, 10:11 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Loading Prior to Catheter Insertion

NCT02883283
View directory record Official record
Conditions
Administration Methods of Labor Analgesia
Interventions
Epidural loading dose, Epidural catheter, Epidural needle
Procedure · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Sep 20, 2026, 10:11 AM EDT
Terminated No phase listed Observational

NIBP (Non-invasive Blood Pressure) Algorithm Enhancements (Characterize the Robustness of Motion Artifact Suppression)

NCT05185037
View directory record Official record
Conditions
Movement, Involuntary
Interventions
Philips IntelliVue X3 patient monitor with investigational NIBP measurement algorithm (measured once per 3 minutes)
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 20, 2026, 10:11 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Real-time Ultrasound Guided Labor Epidural Placement

NCT00811304
View directory record Official record
Conditions
Epidural Anesthesia
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2013 · Synced Sep 20, 2026, 10:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 20, 2026, 10:11 AM EDT
Active, not recruiting Not applicable Interventional

Effects of Musical Intervention on Patient Pain and Anxiety for Office-based Procedures

NCT06235996
View directory record Official record
Conditions
Chronic Pain
Interventions
Office-based procedure indicated for chronic pain with music, Office-based procedure indicated for chronic pain without music
Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Wesley Chapel, Florida • Zephyrhills, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 20, 2026, 10:11 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ambulation With Labor Epidural in Obese Women

NCT04504682
View directory record Official record
Conditions
Obesity, Labor Onset and Length Abnormalities
Interventions
Ambulation
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Phase 2 Interventional

A Randomized Study of the Efficacy of Low Venous Pressure General Anesthesia Versus Combined Spinal-Epidural Anesthesia in Decreasing Blood Loss During Prostate Surgery

NCT00200187
View directory record Official record
Conditions
Prostate Cancer
Interventions
low venous pressure general anesthesia, combined spinal-epidural anesthesia
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Sep 20, 2026, 10:11 AM EDT
Completed No phase listed Observational

Chloroprocaine for Continuous Epidural Analgesia in Neonates and Infants

NCT02207855
View directory record Official record
Conditions
Anesthesia
Interventions
Chloroprocaine
Drug
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 2 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 28, 2016 · Synced Sep 20, 2026, 10:11 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?

NCT01243216
View directory record Official record
Conditions
Pregnancy, Labor Pain
Interventions
Ultrasound
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Sep 20, 2026, 10:11 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures

NCT06533904
View directory record Official record
Conditions
Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency, Pain, Chest, Rib Trauma, Rib Fracture Multiple, Respiratory Failure, Respiratory Distress Syndrome
Interventions
Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
Procedure · Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 20, 2026, 10:11 AM EDT
Recruiting Phase 2Phase 3 Interventional

IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

NCT06559969
View directory record Official record
Conditions
Laparotomy
Interventions
Intravenous administered opioid, Epidural administered opioid
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 20, 2026, 10:11 AM EDT
Active, not recruiting Phase 3 Interventional

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

NCT03214510
View directory record Official record
Conditions
Liver and Intrahepatic Bile Duct Disorder
Interventions
Bupivacaine, Fentanyl, Hydromorphone Hydrochloride, Implanted Medical Device, Liposomal Bupivacaine, Questionnaire
Drug · Device · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Not applicable Interventional

Comparison of Epidural and Paracostal Catheter Placement for Pain Control After Rib Fractures

NCT02295098
View directory record Official record
Conditions
Rib Fractures, Wounds and Injuries
Interventions
Thoracic epidural catheter placement, Paracostal catheter placement
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Sep 20, 2026, 10:11 AM EDT
Recruiting Early Phase 1 Interventional

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

NCT06617949
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
Regional Anesthesia, Hydromorphone Patient Controlled Analgelsic, Epidural local anesthetic infusion
Drug · Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Leg Elevation to Prevent Hypotension During Labor

NCT05674838
View directory record Official record
Conditions
Hypotension, Labor Complication
Interventions
Leg Elevation
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Not applicable Interventional

Comparison Between Epidural and Bilateral Paravertebral Blocks in Liver Resection

NCT01407666
View directory record Official record
Conditions
Liver Disease, Pain
Interventions
paravertebral blocks
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Not applicable Interventional Results available

Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient

NCT01816477
View directory record Official record
Conditions
Pectus Excavatum
Interventions
ON-Q soaker catheter system, Epidural (ropivicaine 0.25%)
Device · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Phase 4 Interventional Results available

Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion

NCT00880607
View directory record Official record
Conditions
Pain Management, Spinal Fusion, Scoliosis
Interventions
Intrathecal morphine, Extended Release Epidural Morphine
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Sep 20, 2026, 10:11 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome

NCT02094352
View directory record Official record
Conditions
Complex Regional Pain Syndrome
Interventions
Ketamine Infusion + Epidural Infusion, Control Group + Epidural infusion, Ketamine Booster Infusion, Control Group Booster Infusion
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Sep 20, 2026, 10:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Music Use in Parturients Admitted to Labor & Delivery

NCT06969105
View directory record Official record
Conditions
Anxiety, Pain, Patient Satisfaction
Interventions
Music
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 20, 2026, 10:11 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section

NCT03383588
View directory record Official record
Conditions
Pain, Referred
Interventions
Bupivacaine, Morphine, Fentanyl, Epinephrine, Saline solution
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
17 Years to 40 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 20, 2026, 10:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia

NCT02412969
View directory record Official record
Conditions
Labor Pain, Labor Analgesia
Interventions
Lumbar Epidural, Dural Puncture Epidural
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Sep 20, 2026, 10:11 AM EDT
Not yet recruiting Phase 4 Interventional

A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device

NCT06729255
View directory record Official record
Conditions
Postdural Puncture Headache, Epidural Analgesia, Obstetric
Interventions
EpiZact-assisted epidural placement
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Sep 20, 2026, 10:11 AM EDT