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ClinicalTrials.gov public records Last synced Nov 5, 2026, 11:55 AM EST

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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Epidural Spinal Cord Stimulation Clear all

Conditions: Paraplegia, Spinal, Paraplegia, Complete, Paraplegia; Traumatic
Interventions: Transcutaneous spinal cord stimulator, Epidural spinal cord stimulation system; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 22 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Phantom Limb
Interventions: Boston Scientific Stimulator Lead; Device
Lead sponsor: Lee Fisher, PhD; Other
Eligibility: 18 Years to 70 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Complex Regional Pain Syndrome
Interventions: The Nuvectra Algovita Dorsal Column Spinal Cord Stimulator, The Axium Neurostimulator System; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Spinal Cord Injuries
Interventions: Exoskeletal assisted walking, Epidural Stimulation, Resistance Training, delayed-ES, no-Resistance training; Device · Procedure
Lead sponsor: United States Department of Defense; Federal
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Spinal Cord Injury at T1-T12 Level, Traumatic Thoracic Spinal Cord Contusion, Thoracic Spinal Cord Trauma, Traumatic Thoracic Spinal Cord Laceration, Post-Traumatic Thoracic Myelopathy, Traumatic Thoracic Spinal Cord Myelopathy
Interventions: EES on, EES off; Device
Lead sponsor: Nandan Lad, M.D., Ph.D.; Other
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Spinal Cord Injuries
Interventions: Epidural stimulation; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 75 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Spinal Cord Injuries
Interventions: Epidural stimulation + Stand Training, Epidural stimulation + Step Training, Epidural stimulation + Bladder Capacity Training, Epidural stimulation + Bladder Voiding Efficiency Training; Combination Product
Lead sponsor: Claudia Angeli; Other
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Spinal Cord Injuries
Interventions: implanted epidural stimulator; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 100 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Spinal Cord Injury
Interventions: Standing and Stepping with spinal cord Epidural Stimulation; Device
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Spinal Cord Injury
Interventions: 5-6-5 Specify electrode, Restore Advance Pulse Generator; Device
Lead sponsor: University of Louisville; Other
Eligibility: 21 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Paraplegia, Tetraplegia, Paralysis, Quadraplegia
Interventions: Percutaneous epidural electrical spinal stimulation, Transcutaneous electrical spinal stimulation; Device
Lead sponsor: Kristin Zhao, PhD; Other
Eligibility: 22 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Chronic Pain, Hypertension, Implanted Stimulation Electrodes
Interventions: Diagnostic Tests; Diagnostic Test
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 30 Years to 89 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 2
States / cities: Fairway, Kansas • Kansas City, Kansas

Conditions: Chronic Pain, Spasticity as Sequela of Stroke, Upper Motor Neuron Lesion
Interventions: Spinal Cord Stimulation- Closed loop; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Spinal Cord Injury, Spinal Cord Injury Cervical
Interventions: Epidural spinal cord stimulation and paired spine and brain stimulation; Device
Lead sponsor: Jason Carmel; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: New York, New York

Conditions: Restless Legs Syndrome, Neuropathic Pain
Interventions: Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement, Continuous Blood Pressure, Partial pressure of oxygen, Microneurography, Anthropometric Measurements, John Hopkins Restless Legs Severity Scale, Continuous Blood Pressure Diary; Diagnostic Test · Other · Behavioral
Lead sponsor: Marshall Holland; Other
Eligibility: 18 Years to 85 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Spinal Cord Injuries
Interventions: Activity-based locomotor training, Activity-based stand training, Activity-based upper arm ergometry, Activity-based training + spinal epidural stimulation; Procedure
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Spinal Cord Injury (SCI), Initial Encounter
Interventions: Epidural Spinal Cord Stimulation, Electrocorticographic, Electroencephalographic; Procedure · Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Miami, Florida

Conditions: Spinal Cord Injury
Interventions: Epidural Stimulator; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Spinal Cord Injuries, Paraplegia, Complete
Interventions: Epidural Spinal Cord Stimulation; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 22 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions: Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP) at or below myelopathic region; Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 3
States / cities: New York, New York

Conditions: Failed Back Surgery Syndrome, Post-Laminectomy Syndrome, Low Back Pain
Interventions: SCS and PNfS, SCS Alone; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 22 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 28
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Little Rock, Arkansas + 24 more

Conditions: Stroke, Spinal Cord Injuries and Disorders, Hemiparesis After Stroke
Interventions: Spinal Cord Stimulator (Medtronic Inceptiv™ System), Physical Therapy; Device · Other
Lead sponsor: Marco Capogrosso; Other
Eligibility: 22 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Spinal Cord Injuries, Blood Pressure Disorders
Interventions: ARC-IM System Implantation, ARC-IM Therapy (Group 1), ARC-IM Therapy (Group 2); Procedure · Device
Lead sponsor: ONWARD Medical, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 12
States / cities: Little Rock, Arkansas • Englewood, Colorado • Miami, Florida + 8 more

Conditions: Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions: Spinal cord stimulator; Device
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia

Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees

Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome

Epidural Stimulation and Resistance Training After SCI

Spinal Cord Stimulation (SCS) for Spinal Cord Injury (SCI)

Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury

Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury

Epi Stim to Facilitate Standing and Stepping

Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity

Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury

Spinal Cord Stimulation for Restless Legs Syndrome

Recovery of Bladder and Sexual Function After Spinal Cord Injury

Assessment of Neural Signals for the Control of Assistive Devices

Spinal Cord Injury Epidural Stimulation

Epidural Stimulation After Neurologic Damage

Spinal Cord Associative Plasticity Study

SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study

Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees