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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Epidural fentanyl Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Labor for Induction Patients

NCT01982851
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects

NCT02159807
View directory record Official record
Conditions
Pregnancy
Interventions
Bupivacaine, Fentanyl
Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Sep 23, 2026, 4:59 PM EDT
Terminated Not applicable Interventional

A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy

NCT03570996
View directory record Official record
Conditions
Esophageal Cancer, Pain, Postoperative
Interventions
Esophagectomy, Transversus abdominis plane catheter, Epidural
Procedure
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 22, 2023 · Synced Sep 23, 2026, 4:59 PM EDT
Completed No phase listed Observational

Intrapartum Epidural Fentanyl/Bupivacaine Analgesia, Infant Feeding Behavior, & Breast-Feeding Outcomes

NCT01260051
View directory record Official record
Conditions
Anesthesia, Epidural, Breast Feeding
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
310 participants
Timeline
2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2022 · Synced Sep 23, 2026, 4:59 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor

NCT00871442
View directory record Official record
Conditions
Labor Pain
Interventions
No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
Other · Drug
Lead sponsor
Neil Roy Connelly, MD
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2015 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Bupivacaine With Epidural Volume Extension

NCT03110003
View directory record Official record
Conditions
Spinal Anesthesia, Epidural; Anesthesia
Interventions
10 mg Bupivacaine, 5 mg Bupivacaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 23, 2026, 4:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Depodur vs Fentanyl Infusion for Post-C/S Analgesia

NCT00762554
View directory record Official record
Conditions
Analgesia
Interventions
Depodur, Fentanyl
Drug
Lead sponsor
Goodman, Evan, M.D.
Individual
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Sep 23, 2026, 4:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Intrapartum Epidural Fentanyl and Breastfeeding in the Immediate Postpartum Period: a Randomized, Controlled, Double-blinded Study

NCT01497509
View directory record Official record
Conditions
Neonatal Neurobehavior, Breastfeeding Outcomes
Interventions
Bolus 10mL 0.25% bupivacaine/ep 1:600,000; infusion 10mL/hour 0.25% bupivacaine and epi 1:800,000, Bolus 10mL 0.25% bupivacaine/ epinephrine 1:600,000;infusion 10mL/hour 0.25% bupivacaine, 2 mcg/mL fentanyl, and epinephrine 1:800,000, Bolus 10mL 0.25% bupivacaine, 10mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 2.5 mcg/mL fentanyl, and epi 1:800,000, Bolus 10mL 0.25% bupivacaine, 5 mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 3.5 mcg/mL fentanyl, and epi 1:800,000
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2022 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Not applicable Interventional Results available

Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery

NCT03915574
View directory record Official record
Conditions
Pain Levels
Interventions
25G Dural Puncture Epidural, Standard Epidural
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Ultrasound Help With Placement of Labor Analgesia in Pregnant Patients?

NCT02207972
View directory record Official record
Conditions
Pregnancy
Interventions
Use of Ultrasound, No ultrasound used
Device · Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of PIEB vs CEI for Labor Analgesia

NCT02949271
View directory record Official record
Conditions
Labor Pain
Interventions
Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Ropivacaine, Fentanyl
Other · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Phase 4 Interventional

Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes

NCT02008591
View directory record Official record
Conditions
Laboring Women Requesting Neuraxial Labor Analgesia
Interventions
Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Combined Spinal-Epidural Versus Traditional Labor Epidural

NCT00151346
View directory record Official record
Conditions
Labour Pain
Interventions
Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2008 · Synced Sep 23, 2026, 4:59 PM EDT
Withdrawn Not applicable Interventional

Regional Anesthesia in Colon Rectal Surgery

NCT00684229
View directory record Official record
Conditions
Colon Cancer
Interventions
Regional anesthesia and analgesia, general anesthesia followed by opioid analgesia
Procedure · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 14, 2016 · Synced Sep 23, 2026, 4:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section

NCT01362998
View directory record Official record
Conditions
Pain
Interventions
Preservative free morphine, Fentanyl
Drug
Lead sponsor
Goodman, Evan, M.D.
Individual
Eligibility
18 Years to 50 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 23, 2026, 4:59 PM EDT
Terminated Phase 4 Interventional Results available

Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

NCT03115151
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine, Hydromorphone, Fentanyl
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Sep 23, 2026, 4:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery

NCT00443560
View directory record Official record
Conditions
Labor Pain, Pregnancy
Interventions
Case controlled analysis of epidural labor analgesia patterns
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
2,162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

DPE Technique in Labor Epidural for Morbidly Obese Women

NCT03074695
View directory record Official record
Conditions
Morbid Obesity, Labor Pain
Interventions
Dural puncture epidural (DPE), Standard Epidural (EPL), Dural puncture epidural (DPE), Standard Epidural (EPL)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor

NCT01621230
View directory record Official record
Conditions
Pregnancy
Interventions
Epidural Bupivacaine plus fentanyl, Epidural fentanyl
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
481 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2020 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CSE v. Epidural for Postpartum Depression

NCT03022526
View directory record Official record
Conditions
Depression, Postpartum, Labor Pain
Interventions
CSE, Epidural, Bupivacaine / fentaNYL
Procedure · Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Sep 23, 2026, 4:59 PM EDT
Terminated Phase 4 Interventional Results available

Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE

NCT01005459
View directory record Official record
Conditions
Labor Pain
Interventions
Tetracaine, Bupivacaine
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
12 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Sep 23, 2026, 4:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Does Ultrasound Help Junior Anesthesia Residents With Placement of Labor Analgesia in Pregnant Patients

NCT02747238
View directory record Official record
Conditions
Pregnancy
Interventions
Ultrasound, No ultrasound, Epidural infusion
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 23, 2026, 4:59 PM EDT
Completed Not applicable Interventional

Continuous Adductor Canal Block (CACB) vs. Combined Spinal Epidural (CSE) in Total Knee Arthroplasty

NCT02415465
View directory record Official record
Conditions
Arthroplasty
Interventions
Continuous Adductor Canal Block, General, Epidural, Spinal
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 23, 2026, 4:59 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Anesthetic Technique on NK Cells

NCT02669186
View directory record Official record
Conditions
Pain, Anesthesia, Cancer
Interventions
Bupivacaine + Fentanyl, Bupivacaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Sep 23, 2026, 4:59 PM EDT