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ClinicalTrials.gov public records Last synced Nov 5, 2026, 8:23 AM EST

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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Erector Spinae Plane Block Clear all

Conditions: Acute Pain, Postoperative, Regional Anesthesia Block
Interventions: Intertransverse Process Block with 1.5% Lidocaine, Erector Spinae Plane Block with 1.5% Lidocaine, 1.5% Lidocaine; Procedure · Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Local Anesthetic Systemic Toxicity, Pain, Quality of Recovery
Interventions: Ropivacaine; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
Interventions: Methadone, Liposomal bupivacaine (LB, Exparel); Drug
Lead sponsor: Dr. Casey Stondell, MD; Other
Eligibility: 11 Years to 17 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Distribution of Ropivacaine in Erector Spinae Plane Block
Interventions: Ropivacaine, Epinephrine; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Pain, Postoperative, Thoracic, Acute Pain
Interventions: Liposomal Bupivacaine, Bupivacaine, 0.25%, Bupivacaine, 0.5%; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Surgical Incision, Pain, Postoperative, Pain, Acute
Interventions: Bupivacaine 0.25%, Normal Saline; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Erector Spinae Plane Block, Pain Control, Post-Operative Pain, Chronic
Interventions: Intravenous Administration of Lidocaine Post Cardiac Surgery, Administration of Lidocaine Post Cardiac Surgery via ESP Catheter; Drug
Lead sponsor: Archit Sharma; Other
Eligibility: 18 Years to 80 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Breast Surgery
Interventions: Erector Spinae (single injection), Paravertebral (single injection); Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Diego, California

Conditions: Anesthesia, Local
Interventions: Ropivacaine; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 6 Months to 18 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Erector Spinae Plane Block
Interventions: Bupivacaine (erector spinae plane block); Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Orange, California

Conditions: Opioid Use, Pain, Postoperative
Interventions: Bupivacaine, Dexamethasone, Saline; Drug · Other
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 80 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer
Interventions: Dexmedetomidine, Liposomal bupivacaine; Drug
Lead sponsor: United States Naval Medical Center, Portsmouth; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Portsmouth, Virginia

Conditions: Congenital Heart Defect, Congenital Heart Disease, Anesthesia, Local, Opioid Use
Interventions: Bilateral Erector Spinae Plane Block (ESPB); Procedure
Lead sponsor: Stanford University; Other
Eligibility: 0 Years to 99 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Renal Colic
Interventions: Ropivacaine injection, Standard of care medications; Drug · Other
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Anesthesia, Conduction
Interventions: Erector Spinae Plane Block, Paravertebral Block; Procedure
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older · Female only
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Rib Fractures, Pain, Acute, Thoracic Injuries, Neuropathic Pain, Neuromuscular Blockade, Anesthesia, Local
Interventions: Erector Spinae Plane Block, Paravertebral Nerve Block; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 85 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Patients With Spinal Stenosis Indicated for MIS TLIF
Interventions: Erector spinae plane (ESP) block; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 80 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
Interventions: Active ropivacaine 0.3% erector spinae plane perineural administration, Placebo erector spinae plane perineural administration; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: San Diego, California

Conditions: Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions: Ropivacaine Hydrocloride; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 10 Years to 18 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pain, Acute Postoperative, Renal Stone
Interventions: Active bupivacaine 0.25% via an erector spinae plane perineural catheter, Placebo normal saline via an erector spinae plane perineural catheter; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: San Diego, California

Conditions: Rib Fractures
Interventions: EPSB for rib fractures, Ropivacaine; Procedure · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain
Interventions: Pre-operative Erector Spinae Plane block prior to DIEP surgery, Pre-operative Transversus Abdominus Plane blocks prior to DIEP surgery; Procedure
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
Interventions: bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Lumbar Radiculopathy
Interventions: Liposomal bupivacaine, Bupivacaine; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 85 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: New York, New York

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Dispersion Following ESP Versus ITP Blocks Using Lidocaine Study

Ropivacaine Pharmacokinetics in ESP Blocks

IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction

Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks

Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures

Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision

Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery

Erector Spinae Versus Paravertebral Nerve Blocks for Breast Surgery

Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population

Nerve Block for Severe Abdominal Pain in the Emergency Department

Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery

Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies

Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study

Erector Spinae Plane (ESP) Block for Renal Colic

Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy

Erector Spinae Plane (ESP) Versus Paravertebral Nerve (PVB) Blockade for Acute Unilateral Rib Fracture Pain

ESP Block in MIS Lumbar Spine Surgery

Continuous Erector Spinae Plane Blocks for Rib Fractures

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

Continuous Erector Spinae Plane Blocks to Treat Pain Following Percutaneous Nephrolithotomy

Ultrasound-guided Erector Spinae Plane Blocks

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain

Erector Spinae Block for Spine Surgery