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ClinicalTrials.gov public records Last synced Oct 5, 2026, 1:06 PM EDT

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Showing 25–48 of 56 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Esophageal Catheter Clear all
Not listed Phase 2 Interventional Accepts healthy volunteers

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

NCT03302858
View directory record Official record
Conditions
HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer, HPV-Related Squamous Cell Carcinoma, Human Papilloma Virus, Human Papillomavirus Infection, Ain III
Interventions
BARRX™ Anorectal Wand
Device
Lead sponsor
Stephen E. Goldstone
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting Not applicable Interventional

Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study

NCT07100379
View directory record Official record
Conditions
Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia, Esophageal Strictures
Interventions
Endoscopic Balloon Dilation
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 5, 2026, 1:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux Disease

NCT00388453
View directory record Official record
Conditions
GERD, Larynx Disease
Interventions
Dx-pH Probe, Manometry
Device · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

NCT00288119
View directory record Official record
Conditions
Barrett's Esophagus, Esophageal Neoplasm
Interventions
Balloon Capsule Device, Endoscopy
Device · Procedure
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2028
U.S. locations
10
States / cities
Baltimore, Maryland • Rochester, Minnesota • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 5, 2026, 1:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of PEEP on Heart and Lungs in Obese Subjects

NCT02523352
View directory record Official record
Conditions
Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging, Respiratory Mechanics, Electrical Impedance Tomography, Trans-Thoracic Echocardiography
Interventions
Non-Invasive Ventilation, Esophageal catheter positioning
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting No phase listed Observational

Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

NCT06475976
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Chest computed tomography (CT) with angiography, Bronchoscopy with bronchoalveolar lavage, Echocardiography, 24 hour esophageal pH ("potential of hydrogen") - multichannel intraluminal impedance (MII) monitoring (reflux testing)
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Month to 1 Year
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 5, 2026, 1:06 PM EDT
Completed No phase listed Observational Results available

Early Detection and Treatment of Esophageal Injury After Catheter Ablation for Atrial Fibrillation

NCT00584922
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Endoscopy in group I (all patients)
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 5, 2026, 1:06 PM EDT
Not listed No phase listed Observational

Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation

NCT02354365
View directory record Official record
Conditions
Transpulmonary Pressure, Pressure.Rate Product, Guide to Mechanical Ventilator Management, Extubation Readiness
Interventions
Transpulmonary Pressure measurement
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Week to 18 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 5, 2026, 1:06 PM EDT
Enrolling by invitation No phase listed Observational

Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device

NCT03103789
View directory record Official record
Conditions
Gastro Esophageal Reflux
Interventions
single catheter mucosal impedance testing, balloon assembly mucosal impedance testing
Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
75 participants
Timeline
2014 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 5, 2026, 1:06 PM EDT
Terminated No phase listed Observational

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

NCT04658342
View directory record Official record
Conditions
Cancer of Head and Neck
Interventions
Videofluoroscopic imaging (VFSS) with high-resolution manometry (HRM)
Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 5, 2026, 1:06 PM EDT
Terminated Phase 4 Interventional Results available

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

NCT00535821
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
Esophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
4
States / cities
Loma Linda, California • Worcester, Massachusetts • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Oct 5, 2026, 1:06 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Comparison of Esophageal Manometry and CT Scan Measurements

NCT04213911
View directory record Official record
Conditions
Morbid Obesity, Respiratory Failure
Interventions
low-dose chest CT scan, insertion of esophageal balloon
Radiation · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 5, 2026, 1:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DreamKit Respiratory Effort Signal Validation

NCT04926077
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Apnea, Central
Interventions
DreamKit
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 30, 2022 · Synced Oct 5, 2026, 1:06 PM EDT
Completed No phase listed Observational

Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Barrett's Epithelium

NCT01633411
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Focal Cryoballoon Ablation System - 6 seconds, Focal Cryoballoon Ablation System - 8 seconds, CryoBalloon Focal Ablation System - 10 seconds
Device
Lead sponsor
Pentax Medical
Industry
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
5
States / cities
Los Angeles, California • Baltimore, Maryland • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting Phase 2 Interventional

Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma

NCT07222657
View directory record Official record
Conditions
Esophageal Adenocarcinoma, Esophageal Cancer
Interventions
Standard of care chemotherapy, LNSC
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 5, 2026, 1:06 PM EDT
Completed No phase listed Observational

Flourish™ Pediatric Esophageal Atresia

NCT03615495
View directory record Official record
Conditions
Esophageal Atresia, Digestive System Abnormalities, Esophageal Disorders Congenital
Interventions
Flourish Pediatric Esphogeal Atresia device
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
Up to 12 Months
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
11
States / cities
Honolulu, Hawaii • Chicago, Illinois • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting Phase 3 Interventional

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

NCT05561114
View directory record Official record
Conditions
Esophageal Stricture
Interventions
GIE Medical ProTractX3 TTS DCB, Control
Combination Product · Other
Lead sponsor
GIE Medical
Industry
Eligibility
22 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
34
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Irvine, California + 29 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 5, 2026, 1:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mucosal Impedance Balloon in Diagnosis and Treatment of Eosinophilic Esophagitis (EoE)

NCT02995395
View directory record Official record
Conditions
Eosinophilic Esophagitis, Healthy
Interventions
Mucosal Impedance Balloon catheter
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Oct 5, 2026, 1:06 PM EDT
Completed No phase listed Observational

Food Antigen in Eosinophilic Esophagitis

NCT02434705
View directory record Official record
Conditions
Eosinophilic Esophagitis
Interventions
Antigen (wheat base soy sauce) spray
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Oct 5, 2026, 1:06 PM EDT
Completed Not applicable Interventional

Pharyngeal Anatomy In Obstructive Sleep Apnea With HRM

NCT03198416
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
High-resolution pharyngeal manometry catheter
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 26, 2024 · Synced Oct 5, 2026, 1:06 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

[Impedance Measurement for Non-Erosive Reflux Disease

NCT02997527
View directory record Official record
Conditions
GERD, Healthy
Interventions
Intraluminal Impedance
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting Not applicable Interventional

Esophageal Temperature During PVI Using Q-DOT Micro

NCT06392932
View directory record Official record
Conditions
Atrial Fibrillation Paroxysmal
Interventions
QDOT Micro ablation catheter, ST SF ablation catheter
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 5, 2026, 1:06 PM EDT
Terminated Not applicable Interventional

A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy

NCT03570996
View directory record Official record
Conditions
Esophageal Cancer, Pain, Postoperative
Interventions
Esophagectomy, Transversus abdominis plane catheter, Epidural
Procedure
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2023 · Synced Oct 5, 2026, 1:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

High Resolution Pharyngeal Manometry (HRPM) Biofeedback

NCT07508059
View directory record Official record
Conditions
Healthy
Interventions
Swallowing Maneuvers, High Resolution Pharyngeal Manometry (HRPM)
Other · Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 5, 2026, 1:06 PM EDT