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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Essential Oil 2 Clear all
Completed Phase 4 Interventional

A Study of Mouth Rinses in Type 1 and Type 2 Diabetic Participants

NCT04449952
View directory record Official record
Conditions
Gingivits in Diabetics
Interventions
Listerine Cool Mint, 5% Hydroalcohol Mouth Rinse, Colgate Cavity Protection Toothpaste, Alcohol-Free Essential Oil Containing (AFEO) Mouth Rinse Lead Formula, Concept Curve Winter Series Toothbrush, Listerine Cool Mint Floss
Other · Device
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Aromatherapy for Integrated Cancer Care

NCT03449511
View directory record Official record
Conditions
Cancer
Interventions
Ginger aromatherapy, Orange aromatherapy, Lavender aromatherapy, Jojoba aromatherapy
Other
Lead sponsor
University of Rochester
Other
Eligibility
8 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Buffalo, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashes

NCT06136455
View directory record Official record
Conditions
Healthy
Interventions
Listerine Clinical Solutions Teeth Strength, Listerine Total Care Zero Alcohol Mouthwash, Listerine Cool Mint Zero Alcohol Mouthwash, Colgate Cavity Protection Toothpaste
Drug · Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fluid Volume During Fluid Shifts

NCT03447574
View directory record Official record
Conditions
Development of Non-invasive Protocol
Interventions
ethanol dilution
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pharmacokinetics of Essential Oils in Different Capsules

NCT07581522
View directory record Official record
Conditions
Healthy, Health, Subjective
Interventions
Frankinscense Essential Oil Capsule, Lemon Essential Oil Capsule, Wild Orange Essential Oil Capsule
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Omega 3 Fatty Acid Trial

NCT00586222
View directory record Official record
Conditions
Omega-3 Fatty Acids, Pediatric Bipolar Disorder, Adolescent Bipolar Disorder, Magnetic Resonance Spectroscopy Imaging
Interventions
Omega-3 Fatty Acid, Placebo
Dietary Supplement · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 24, 2012 · Synced Sep 10, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

AROMA-NT: Essential Oils and Wearable TENS Device for Chronic Nausea

NCT07720336
View directory record Official record
Conditions
Chronic Nausea, Anxiety
Interventions
Inhaled Essential Oils, Wearable TENS Device
Other · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 10, 2026, 1:27 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Topical Eucalyptus Globulus and Mentha x Piperita on Muscle Soreness in Older Adults and the Elderly

NCT04866407
View directory record Official record
Conditions
Muscle Soreness
Interventions
Mentha x piperita, Eucalyptus globulus
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Freehold, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Sep 10, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes

NCT05208164
View directory record Official record
Conditions
Type 2 Diabetes, Sleep, Stress
Interventions
Mindfunlness Meditation
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Phase 3 Interventional Results available

The Effect of Aromatherapy on Neonatal Abstinence Syndrome and Salivary Cortisol Levels

NCT03097484
View directory record Official record
Conditions
Neonatal Abstinence Syndrome, Aromatherapy
Interventions
lavender and chamomile essential oils
Drug
Lead sponsor
John M. Daniel
Other
Eligibility
Up to 2 Weeks
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Commercial "Sleep Lotion" on Salivary Melatonin Levels and Sleep Quality in Undergraduates

NCT06053385
View directory record Official record
Conditions
Sleep
Interventions
Melatonin sleep lotion, Placebo control lotion
Other
Lead sponsor
University of Redlands
Other
Eligibility
18 Years to 24 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Redlands, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aromatherapy for Stress and Burnout Among Healthcare Providers

NCT05114655
View directory record Official record
Conditions
Stress, Burnout, Professional, Stress, Job
Interventions
Herbaceous Essential Oil Blend, Citrus Essential Oil Blend, Inert Oil
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
20 Years to 59 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Franklin, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Implementing a Nurse-Driven Aromatherapy Protocol to Decrease the Effect of Postoperative Nausea and Vomiting

NCT04822844
View directory record Official record
Conditions
Postoperative Nausea and Vomiting (PONV)
Interventions
Lavender Essential Oil, Ginger Essential Oil
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Pasadena, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 10, 2026, 1:27 AM EDT
Terminated Early Phase 1 Interventional

Aromatherapy for Chemotherapy-induced Symptoms

NCT02670941
View directory record Official record
Conditions
Chemotherapy Symptoms
Interventions
Ginger, Lavender, Orange, Jojoba
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Essential Oils Following IUD Insertion

NCT04927741
View directory record Official record
Conditions
Pain, Muscle, IUD
Interventions
Sweet Marjoram Essential Oil, Grapeseed Oil
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Green Bay, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Assess a Dietary Supplement on Sleep Health and Quality

NCT05368909
View directory record Official record
Conditions
Sleep Quality, Sleep Health
Interventions
Sleep Supplement, Placebo
Dietary Supplement
Lead sponsor
4Life Research, LLC
Industry
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sandy City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Phase 1 Interventional

Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

NCT01381354
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Progressive exercise, Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV, Modified paleolithic diet, Omega 3 fatty acids, Full Spectrum vitamin, Essential - hydroxytyrosol, Maltodextrin fiber supplement, Mineral boost (magnesium), Niacinamide, Methyl B12, Taurine, creatine, thiamine, riboflavin, N acetylcysteine, alpha lipoic acid, L acetyl carnitine, methyl folate, coenzyme Q, meditation, self massage, learning, Coconut oil
Other · Device · Dietary Supplement + 1 more
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Nutrient Levels Alter Transplant Outcome

NCT00560014
View directory record Official record
Conditions
Chronic Renal Disease
Interventions
Arginine and canola oil, Coromega and Arginine
Dietary Supplement
Lead sponsor
University of Cincinnati
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2005
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2007 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic and Epigenetic Impact of FAAH Inhibitors and OEA

NCT07127445
View directory record Official record
Conditions
Healthy
Interventions
OEA supplement
Dietary Supplement
Lead sponsor
Nicole Stevens, PhD
Industry
Eligibility
18 Years to 64 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pleasant Grove, Utah
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing Chemotherapy

NCT02445378
View directory record Official record
Conditions
Acute Leukemia, Anorexia, Anxiety, Depression, Dyspnea, Insomnia, Nausea, Pain
Interventions
Aromatherapy and Essential Oils, Placebo, Questionnaire Administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Aroma on Fatigue Scores Among Women With Hypothyroidism

NCT03465176
View directory record Official record
Conditions
Fatigue, Hypothyroidism
Interventions
Aromatherapy Blend, Placebo
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Franklin, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 31, 2018 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Acupuncture Therapy for COVID-Related Olfactory Loss

NCT04952389
View directory record Official record
Conditions
Olfactory Dysfunction, COVID-19
Interventions
Acupuncture Therapy, Budesonide, Olfactory Training
Device · Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 10, 2026, 1:27 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families

NCT07218328
View directory record Official record
Conditions
Pediatric Cancer
Interventions
FoodiiS plus Culinary Essentials Food Delivery, Culinary Essentials Food Delivery Only, Waitlist control
Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 10, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Computerized DBT Skills Training for Suicidal and Heavy Episodic Drinkers

NCT02932241
View directory record Official record
Conditions
Suicidal Ideation, Alcohol Drinking
Interventions
Computerized Dialectical Behavior Therapy Skills Training
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Sep 10, 2026, 1:27 AM EDT